MIT «MAGAININ» VERWANDTE WÖRTER IM WÖRTERBUCH ENGLISCH
magainin
peptide
structure
pharmaceuticals
sequence
magainin
class
antimicrobial
peptides
found
african
clawed
frog
xenopus
laevis
they
were
discovered
michael
zasloff
first
reported
activity
synthetic
several
demonstrate
that
appear
indistinguishable
from
studies
conclusively
potent
anaspec
related
magainins
antibiotics
with
antibacterial
antiparasitic
activities
originally
extracted
hplc
sigma
aldrich
offers
your
research
needs
find
product
specific
information
including
msds
protocols
references
interactions
outer
isolated
skin
have
broad
spectra
toxicities
normal
eukaryotic
cells
10 BÜCHER, DIE MIT «MAGAININ» IM ZUSAMMENHANG STEHEN
Entdecke den Gebrauch von
magainin in der folgenden bibliographischen Auswahl. Bücher, die mit
magainin im Zusammenhang stehen und kurze Auszüge derselben, um seinen Gebrauch in der Literatur kontextbezogen darzustellen.
1
Transdermal Drug Delivery Enhanced by
Magainin Peptide
The world-wide transdermal drug delivery market is quite large, but only a small number of agents have FDA approval.
Over the next two years, Zasloff and his colleagues determined magainin's
chemical structure, then synthesized it in the laboratory (so they wouldn't have to
kill frogs any longer). They also verified that magainins work like several other
animal ...
3
ANNUAL REPORTS IN MED CHEMISTRY V27 PPR
2) results in an increase in their antimicrobial and antiprotozoan activity (23—24).
in contrast, the analog magainin H, which contains D-alanine at three positions in
magainin 2 (Fig.2), does not exhibit any antimicrobial or antiprotozoan activity ...
4
Membrane Structure in Disease and Drug Therapy
hand, hacterial cells are depolarized immediately on exposure to magainin (98,
99), and decoupling of the respiratory free energy transduction of mitochondria
and spermatozoa (l00) has heen reported, although the cells are not physically ...
5
Bioactive Proteins and Peptides as Functional Foods and ...
It was shown that magainin alone had no effect on skin permeability, probably
because the relatively large magainin molecule had difficulty penetrating
throughout the stratum corneum to make continuous transdermal pathways.
However ...
Yoshinori Mine, PhD, Eunice Li-Chan, Bo Jiang, 2011
6
Development of Therapeutic Agents Handbook
... 26 KWKSFlKTFKSAvKTvlHTAlKAISS Y 0 7 Cecropin A (1– 8) + melittin B (1–18
) derivative (v681: v13K) 26 KWKSFlKTFKSAKKTvlHTAlKAISS Y 0 8 Magainin 2
23 GIGKFlHSAKKFGKAFvGEIMNS Y 0 5 Cecropin A (1– 8) + magainin 2 (1–12)
...
7
Modern Magnetic Resonance: Part 1: Applications in ...
Solid-State NMR Experiments: Peptide Orientation in Bilayers Magainin 2 As a
classical example of amphipathic oc-helical antimicrobial peptides, magainin,
and its natural and synthetic analogues have been intensively studied [64].
8
Frontiers in Medicinal Chemistry , Volume (1)
Haung and co-workers also showed that the protegrin [166], alamethicin [167],
melittin [168], and magainin [169] peptides all exhibit different circular dichroism
spectra, one at high peptide/lipid ratios and the other at low peptide/lipid ratios.
Atta-ur-Rahman, Allen B. Reitz, M. Iqbal Choudhary, 2004
9
Planar Lipid Bilayers (BLM's) and Their Applications
6.3.2 Single channel recording and conductance dependence on the membrane
voltage Planar lipid membranes were used to see whether and in which
experimental conditions magainin 2 at a concentration of 4.05*10-8M is able to
fonn ...
H.T. Tien †, A. Ottova-Leitmannova, 2003
10
Cell Physiology Sourcebook: Essentials of Membrane Biophysics
This can be accomplished if the monomeric units become slightly less compact
by allowing Leu 13 to adopt the a-helical conformation. The sacrifice in
conformational energy is about 3 kcal/mol (Kempf et al., 1982). Magainin This 23-
residue ...
Nicholas Sperelakis, 2012
10 NACHRICHTEN, IN DENEN DER BEGRIFF «MAGAININ» VORKOMMT
Erfahre, worüber man in den einheimischen und internationalen Medien spricht und wie der Begriff
magainin im Kontext der folgenden Nachrichten gebraucht wird.
Egalet Appoints Nicholas Nicolaides, Ph.D. and John Osborn to …
Prior to co-founding Morphotek, Dr. Nicolaides was the director of research at Magainin Pharmaceuticals, where his research focused on the ... «PR Newswire, Apr 15»
MicuRx Expands Global Clinical Trial Program For Oral Antibiotic …
... by Forest Laboratories), Peninsula Pharmaceuticals (acquired by J&J Pharmaceuticals), Genesoft Inc, and Magainin Pharmaceuticals Inc. He ... «PR Newswire, Dez 13»
Why the Biotech Industry Is Rejoicing over the End of Gene Patents
... Valley-based biotech company. Magainin Pharmaceuticals, in Pennsylvania, holds several patents on genes related to asthma and allergies. «Motherboard, Jun 13»
AltheRx Pharmaceuticals Appoints Michael R Dougherty to Board of …
... including Genaera Corporation, (formerly Magainin Pharmaceuticals Inc.) and Centocor, Inc. Michael is currently a member of the Board of ... «Business Wire, Mai 13»
Is Frog Skin a Red Herring?
The AMP that came closest to success—a compound called magainin, derived from the skin of the African clawed frog—passed through Phase ... «Scientist, Jan 13»
Former Genaera home to become new tech center
(originally founded in 1988 as Magainin Pharmaceuticals) to turn it into the Montgomery County Technology Center. “The trend is Big Pharma ... «Philadelphia Business Journal, Mai 12»
Synaptic Capital hedge fund targets healthcare sector
He started his career as a peptide chemist with Magainin Pharmaceuticals before moving to Pain Weber as an associate analyst in ... «MedCity News, Nov 11»
Dolphins: Sponge-worthy? Yes. Antimicrobial? Maybe
He founded the company Magainin Pharmaceuticals in 1988 to develop those compounds for therapies, but it was nearly destroyed when the ... «PLoS Blogs, Jul 11»
Nanoparticles successfully take down MRSA bacteria
An example of the charged peptides is magainin, named from the Hebrew word for shield, magain. It was isolated from frogs after an observant ... «Ars Technica, Apr 11»
The Dendreon Fraud: Joel Sendek of Lazard Research and …
Magainin/Genaera, the company that was run by ProQuest's ostensible founder, Jay Moorin, had lots of big ideas. For example, it claimed to ... «Market Rap, Jul 09»