A noun is a type of word the meaning of which determines reality. Nouns provide the names for all things: people, objects, sensations, feelings, etc.
WHAT DOES ANTIMETABOLITE MEAN IN ENGLISH?
An antimetabolite is a chemical that inhibits the use of a metabolite, which is another chemical that is part of normal metabolism. Such substances are often similar in structure to the metabolite that they interfere with, such as the antifolates that interfere with the use of folic acid. The presence of antimetabolites can have toxic effects on cells, such as halting cell growth and cell division, so these compounds are used as chemotherapy for cancer.
Definition of antimetabolite in the English dictionary
The definition of antimetabolite in the dictionary is any drug that acts by disrupting the normal growth of a cell. Sulfonamide drugs are antimetabolites and some antimetabolites are used in cancer treatment.
The translations of antimetabolite from English to other languages presented in this section have been obtained through automatic statistical translation; where the essential translation unit is the word «antimetabolite» in English.
List of principal searches undertaken by users to access our English online dictionary and most widely used expressions with the word «antimetabolite».
FREQUENCY OF USE OF THE TERM «ANTIMETABOLITE» OVER TIME
The graph expresses the annual evolution of the frequency of use of the word «antimetabolite» during the past 500 years. Its implementation is based on analysing how often the term «antimetabolite» appears in digitalised printed sources in English between the year 1500 and the present day.
Examples of use in the English literature, quotes and news about antimetabolite
10 ENGLISH BOOKS RELATING TO «ANTIMETABOLITE»
Discover the use of antimetabolite in the following bibliographical selection. Books relating to antimetabolite and brief extracts from same to provide context of its use in English literature.
Mutants resistant to an antimetabolite. View of a petri dish with nutrient agar
containing an antimetabolite; this has been inoculated with about 108 bacteria.
Only colonies of resistant mutants grow at first. The zones of the large colonies (of
Hans Günter Schlegel, C. Zaborosch, 1993
Metabolic Inhibitors V1: A Comprehensive Treatise
C. Reversibility, Competitive and Noncompetitive As mentioned above, the
reaction of the substrate with its enzyme is reversible, and so also the reaction of
the antimetabolite with the enzyme may be. If it is, then the inhibition of the
R Hochster, 2012
The First Miracle Drugs : How the Sulfa Drugs Transformed ...
The first was taken when Fildes proposed a rational program for research in
bacterial chemotherapy. The second was taken when other researchers
formulated the antimetabolite concept, which applied to other microbes and to
cells of larger ...
Berkeley John E. Lesch Professor of History University of California, 2006
Anticancer drugs: antimetabolite metabolism and natural ...
The anticancer drugs embody a diverse array of chemical structures. The purpose of this two volume publication is to provide a comprehensive review of the metabolism of anticancer drugs.
Connie Henke Yarbro, Margaret Hansen Frogge, Michelle Goodman, 2004
Clinical Companion for Pediatric Nursing
Antineoplastic agents used to treat ALL include asparaginase (enzyme),
corticosteroids, cyclophospharnide (alkylating agent), cytarabine (antimetabolite),
daunorubicin (antibiotic), doxorubicin (antibiotic), etoposide (plant alkaloid),
Bonita Broyles, 2008
Pearls of Glaucoma Management
Some surgeons first needle and then inject antimetabolite at a site distal to the
bleb revision site. Other surgeons will raise a subconjunctival bleb prior to
needling, which helps dissect tissue and makes it safer to track the needle under
JoAnn A. Giaconi, Simon K. Law, Anne L. Coleman, 2010
The Washington Manual Hematology and Oncology Subspecialty ...
Additional antimetabolite complications include corneal toxicity, uveitis, and
suprachoroidal hemorrhage. An isolated bleb leak must be carefully observed.
Fortunately, the majority of them resolve with antibiotic prophylaxis alone and do
John R. Samples, Paul N. Schacknow, 2013
Cataract Surgery in the Glaucoma Patient: Bd. 22
This reduces the chance of contamination of any instruments and is in line with
general antimetabolite handling policy. Watertight wound healing is critical at the
conjunctival free edge, as otherwise there is a risk of a postoperative wound leak.
Sandra M. Johnson, 2010
10 NEWS ITEMS WHICH INCLUDE THE TERM «ANTIMETABOLITE»
Find out what the national and international press are talking about and how the term antimetabolite is used in the context of the following news items.
Dr. Howard S. Hochster on TAS-102 Compared to 5FU
It is a different kind of antimetabolite than 5-fluorouracil (5-FU) and is active in 5FU- resistant cells pre-clinically, says Hochster. The drug has a ... «OncLive, Jul 15»
mTOR inhibitor versus mycophenolic acid as the primary …
... it has largely replaced azathioprine (AZA) as the antimetabolite immunosuppressive of choice in kidney transplantation –. The current ... «BMC Blogs Network, Jun 15»