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Meaning of "ciclosporin" in the English dictionary

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DICTIONARY
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PRONUNCIATION OF CICLOSPORIN

ciclosporin  [ˌsaɪkləʊˈspɔːrɪn] play
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GRAMMATICAL CATEGORY OF CICLOSPORIN

noun
adjective
verb
adverb
pronoun
preposition
conjunction
determiner
exclamation
Ciclosporin is a noun.
A noun is a type of word the meaning of which determines reality. Nouns provide the names for all things: people, objects, sensations, feelings, etc.

WHAT DOES CICLOSPORIN MEAN IN ENGLISH?

Ciclosporin

Ciclosporin ; cyclosporine; cyclosporin; or ciclosporin A, cyclosporine A, or cyclosporin A is an immunosuppressant drug widely used in organ transplantation to prevent rejection. It reduces the activity of the immune system by interfering with the activity and growth of T cells. It was initially isolated from the fungus Tolypocladium inflatum, found in a soil sample obtained in 1969 from Hardangervidda, Norway, by Hans Peter Frey, a Sandoz biologist. Most peptides are synthesized by ribosomes, but ciclosporin is a cyclic nonribosomal peptide of 11 amino acids and contains a single D-amino acid, which are rarely encountered in nature.

Definition of ciclosporin in the English dictionary

The definition of ciclosporin in the dictionary is a drug extracted from a fungus and used after organ transplantation to suppress the body's immune mechanisms, and so prevent rejection of an organ.

WORDS THAT RHYME WITH CICLOSPORIN


antiarin
ˌæntɪˈɑːrɪn
aquaporin
ˌækwəˈpɔːrɪn
Catherine
ˈkæθrɪn
cephalosporin
ˌsɛfələʊˈspɔːrɪn
chlorin
ˈklɔːrɪn
cyclosporin
ˌsaɪkləʊˈspɔːrɪn
doctrine
ˈdɒktrɪn
Drin
drɪn
Erin
ˈɪərɪn
euchlorin
juːˈklɔːrɪn
foreign
ˈfɒrɪn
grin
ɡrɪn
Katherine
ˈkæθərɪn
laminarin
ˌlæmɪˈnɑːrɪn
mandarin
ˈmændərɪn
Marin
ˈmɑːrɪn
sovereign
ˈsɒvrɪn
transferrin
trænsˈfɜːrɪn
Turin
tjʊəˈrɪn
urine
ˈjʊərɪn

WORDS THAT BEGIN LIKE CICLOSPORIN

cicatrization
cicatrize
cicatrizer
cicelies
cicely
cicero
cicerone
ciceroni
Ciceronian
cichlid
Cichlidae
cichloid
cichoraceous
cicinnus
cicisbei
cicisbeism
cicisbeo
ciclaton
Cicuta
cicutine

WORDS THAT END LIKE CICLOSPORIN

aequorin
aspirin
brin
Cape Comorin
chagrin
chlorocruorin
Comorin
fiorin
fluorin
glycerin
heparin
Ilorin
Kirin
navarin
Perrin
Schwerin
serin
taborin
trin
warfarin

Synonyms and antonyms of ciclosporin in the English dictionary of synonyms

SYNONYMS

Translation of «ciclosporin» into 25 languages

TRANSLATOR
online translator

TRANSLATION OF CICLOSPORIN

Find out the translation of ciclosporin to 25 languages with our English multilingual translator.
The translations of ciclosporin from English to other languages presented in this section have been obtained through automatic statistical translation; where the essential translation unit is the word «ciclosporin» in English.

Translator English - Chinese

环孢素
1,325 millions of speakers

Translator English - Spanish

ciclosporina
570 millions of speakers

English

ciclosporin
510 millions of speakers

Translator English - Hindi

ciclosporin
380 millions of speakers
ar

Translator English - Arabic

سيكلوسبورين
280 millions of speakers

Translator English - Russian

циклоспорин
278 millions of speakers

Translator English - Portuguese

ciclosporina
270 millions of speakers

Translator English - Bengali

ciclosporin
260 millions of speakers

Translator English - French

ciclosporine
220 millions of speakers

Translator English - Malay

Ciclosporin
190 millions of speakers

Translator English - German

Ciclosporin
180 millions of speakers

Translator English - Japanese

シクロスポリン
130 millions of speakers

Translator English - Korean

사이클로스포린
85 millions of speakers

Translator English - Javanese

Ciclosporin
85 millions of speakers
vi

Translator English - Vietnamese

ciclosporin
80 millions of speakers

Translator English - Tamil

ciclosporin
75 millions of speakers

Translator English - Marathi

कॉकालस्पोरिन
75 millions of speakers

Translator English - Turkish

siklosporin
70 millions of speakers

Translator English - Italian

ciclosporina
65 millions of speakers

Translator English - Polish

cyklosporyna
50 millions of speakers

Translator English - Ukrainian

циклоспорин
40 millions of speakers

Translator English - Romanian

ciclosporină
30 millions of speakers
el

Translator English - Greek

κυκλοσπορίνη
15 millions of speakers
af

Translator English - Afrikaans

siklosporien
14 millions of speakers
sv

Translator English - Swedish

ciklosporin
10 millions of speakers
no

Translator English - Norwegian

ciklosporin
5 millions of speakers

Trends of use of ciclosporin

TRENDS

TENDENCIES OF USE OF THE TERM «CICLOSPORIN»

The term «ciclosporin» is regularly used and occupies the 103.575 position in our list of most widely used terms in the English dictionary.
0
100%
FREQUENCY
Regularly used
52
/100
The map shown above gives the frequency of use of the term «ciclosporin» in the different countries.
Principal search tendencies and common uses of ciclosporin
List of principal searches undertaken by users to access our English online dictionary and most widely used expressions with the word «ciclosporin».

FREQUENCY OF USE OF THE TERM «CICLOSPORIN» OVER TIME

The graph expresses the annual evolution of the frequency of use of the word «ciclosporin» during the past 500 years. Its implementation is based on analysing how often the term «ciclosporin» appears in digitalised printed sources in English between the year 1500 and the present day.

Examples of use in the English literature, quotes and news about ciclosporin

EXAMPLES

10 ENGLISH BOOKS RELATING TO «CICLOSPORIN»

Discover the use of ciclosporin in the following bibliographical selection. Books relating to ciclosporin and brief extracts from same to provide context of its use in English literature.
1
Side Effects of Drugs Annual: A worldwide yearly survey of ...
[SED-15, 743; SEDA-32, 705; SEDA-33, 815; SEDA-34, 609] Observational studies In a prospective multicenter study of a 12-month course of ciclosporin in 35 children with steroid-resistant nephritic syndrome, of whom 28 had minimal change ...
Jeffrey K Aronson, 2014
2
Clinical Pharmacokinetics
Elimination Clearance of ciclosporin from the body is predominantly hepatic, via the hepatobiliary tract. Ciclosporin is a drug with a low to intermediate extraction ratio. It does not undergo excessive first-pass metabolism and extraction of the ...
Soraya Dhillon, Andrzej Kostrzewski (MRPharmS.), 2006
3
Meyler's Side Effects of Analgesics and Anti-inflammatory Drugs
Bisphosphonates In an analysis of changes in ciclosporin clearance and systemic availability obtained from the medical records of 100 transplant patients, alendronic acid altered ciclosporin pharmacokinetics (305). Calcium channel blockers ...
Jeffrey K. Aronson, 2009
4
Clinical Trials in Rheumatology
This book is a valuable reference tool for rheumatologists and other clinical specialties, as well as for research scientists interested in immunomodulatory and selected other drug therapies in rheumatologic diseases.
Ruediger Mueller, Johannes von Kempis, 2012
5
Transplantation: Companion to Specialist Surgical Practice
Patients were randomised to receive either belatacept MI, belatacept LI or ciclosporin. Lymphocyte—depleting therapy was allowed for anticipated delayed graft function in ciclosporin—treated patients. Patients with acute rejection ZGrade IIB ...
John L. R. Forsythe, 2013
6
Meyler's Side Effects of Herbal Medicines
The drugs that were affected included amitriptyline, ciclosporin, digoxin, indinavir, irinotecan, mycophenolic acid, omeprazole, oral contraceptives, tacrolimus, theophylline, and warfarin. The mechanism of hepatic enzyme induction by St.
J. K. Aronson, 2009
7
WHO Model Formulary 2008
Fluconazole Metabolism of ciclosporin inhibited (increased plasma concentration ) * Gentamicin Increased risk of nephrotoxicity * Grapefruit juice Increased plasma ciclosporin concentration (risk of toxicity) Griseofulvin Plasma ciclosporin  ...
Mark C. Stuart, Maria Kouimtzi, Suzanne Hill, 2009
8
Meyler's Side Effects of Endocrine and Metabolic Drugs
Thyroid Life-threatening hypothyroidism associated with ciclosporin was reported in a patient treated with reducedintensity hemopoietic stem cell transplantation for metastatic renal-cell carcinoma (50). A 26 year old woman with metastatic ...
Jeffrey K. Aronson, 2009
9
Pharmaceutical Companies: 2011 Edition
A report, 'Moxifloxacin does not alter ciclosporin pharmacokinetics in transplant patients: a multiple-dose, uncontrolled, single-centre study,' is newly published data in Clinical Drug Investigation. “Moxifloxacin has a broad antibacterial ...
‎2012
10
Evidence-Based Dermatology
Be sure your skin-care treatments have strong evidential support Evidence-based Dermatology, Third Edition takes a unique approach to clinical dermatology by emphasising use of only the highest quality available evidence when treating ...
Michael Bigby, Andrew Herxheimer, Luigi Naldi, 2014

10 NEWS ITEMS WHICH INCLUDE THE TERM «CICLOSPORIN»

Find out what the national and international press are talking about and how the term ciclosporin is used in the context of the following news items.
1
New treatments urgently needed for rare, disfiguring and painful skin …
The STOP GAP trial set out to determine which of the two most commonly used treatments for PG—ciclosporin and prednisolone—was most ... «Medical Xpress, Jul 15»
2
mTOR inhibitor versus mycophenolic acid as the primary …
... (MMF) or enteric-coated mycophenolate sodium (EC-MPS)) with a calcineurin inhibitor (CNI: tacrolimus or ciclosporin A) and corticosteroid. «BMC Blogs Network, Jun 15»
3
Global Ophthalmic Drugs Market – Data, Analysis and Forecasts to …
In December 2013 Santen announced that Ikervis (Ciclosporin / Cyclokat) was filed to the EMA, in doing so the EMA will begin its regulatory ... «Medgadget.com, Jun 15»
4
NICE considers ciclosporin recommendation for dry eye
The National Institute for Health and Care Excellence (NICE) has today (June 23) published guidance on the use of ciclosporin for dry eye ... «Optometry Today, Jun 15»
5
Latest decisions on medicines approved for NHS use announced
Use is restricted to patients who have failed to respond to standard systemic therapies (including ciclosporin, methotrexate and phototherapy), ... «Today's GP, Jun 15»
6
Boost in access to new treatments for psoriasis
... have a contraindication to, or are intolerant to other systemic therapy including ciclosporin, methotrexate or psoralen and ultraviolet-A light. «Nursing Times, Jun 15»
7
Data at EULAR 2015 Showcase Commitment of Janssen to …
... failed to respond to, or who have a contraindication to, or are intolerant to other systemic therapies including ciclosporin, methotrexate (MTX) ... «Yahoo Finance UK, Jun 15»
8
The latest lessons in anticoagulation safety
“Strong P-gp inhibitors such as dronedarone, and the azoles, tacrolimus and ciclosporin, are generally contraindicated. Mild to moderate P-gp ... «Irish Medical Times, May 15»
9
STELARA® Receives CHMP Positive Opinion for Treatment of …
... or are intolerant to other systemic therapies including ciclosporin, methotrexate (MTX) or psoralen plus ultraviolet A (PUVA). STELARA is also ... «Business Wire, May 15»
10
The Safety of Therapeutic Drugs in Male Inflammatory Bowel …
... 'azathioprine AND infertility,' 'methotrexate AND infertility,' 'ciclosporin AND infertility,' 'corticosteroids AND infertility,' 'infliximab AND male fertility,' 'infliximab ... «Medscape, May 15»

REFERENCE
« EDUCALINGO. Ciclosporin [online]. Available <https://educalingo.com/en/dic-en/ciclosporin>. Apr 2024 ».
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