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Meaning of "clozapine" in the English dictionary

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DICTIONARY
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PRONUNCIATION OF CLOZAPINE

clozapine  [ˈkləʊzəˌpiːn] play
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GRAMMATICAL CATEGORY OF CLOZAPINE

noun
adjective
verb
adverb
pronoun
preposition
conjunction
determiner
exclamation
Clozapine is a noun.
A noun is a type of word the meaning of which determines reality. Nouns provide the names for all things: people, objects, sensations, feelings, etc.

WHAT DOES CLOZAPINE MEAN IN ENGLISH?

Clozapine

Clozapine is an atypical antipsychotic medication used in the treatment of schizophrenia, and is also sometimes used off-label for the treatment of bipolar disorder. The first of the atypical antipsychotics to be developed, it was first introduced in Europe in 1971, but was voluntarily withdrawn by the manufacturer in 1975 after it was shown to cause agranulocytosis, a condition involving a dangerous decrease in the number of white blood cells, that led to death in some patients. In 1989 after studies demonstrated that it was effective in treating treatment-resistant schizophrenia the United States Food and Drug Administration approved the use of clozapine solely for that use, requiring regular white blood cell and absolute neutrophil counts. The FDA also requires clozapine to carry five black box warnings for agranulocytosis, seizures, myocarditis, for "other adverse cardiovascular and respiratory effects", and for "increased mortality in elderly patients with dementia-related psychosis." In 2002 the FDA approved clozapine for reducing the risk of suicidal behavior for patients with schizophrenia.

Definition of clozapine in the English dictionary

The definition of clozapine in the dictionary is medication used to treat mental illness.

WORDS THAT RHYME WITH CLOZAPINE


alepine
ˈælɪˌpiːn
alpeen
ˈælpiːn
atropine
ˈætrəˌpiːn
benzodiazepine
ˌbɛnzəʊdaɪˈeɪzəˌpiːn
carbamazepine
ˌkɑːbəˈmæzəˌpiːn
chiltepin
ˌtʃɪlteɪˈpiːn
chopine
tʃɒˈpiːn
fillipeen
ˌfɪləˈpiːn
hemiterpene
ˌhɛmɪˈtɜːpiːn
Lycopene
ˈlaɪkəˌpiːn
monoterpene
ˈmɒnəˌtɜːpiːn
nifedipine
naɪˈfɛdɪpiːn
peen
piːn
Philippine
ˈfɪlɪˌpiːn
polypropene
ˌpɒlɪˈprəʊpiːn
propene
ˈprəʊpiːn
sesquiterpene
ˌsɛskwɪˈtɜːpiːn
spalpeen
ˈspælpiːn
terpene
ˈtɜːpiːn
tropine
ˈtrəʊpiːn

WORDS THAT BEGIN LIKE CLOZAPINE

clovis point
clow
clowder
clown
clownery
clownfish
clowning
clownish
clownishly
clownishness
cloxacillin
cloy
cloye
cloying
cloyingly
cloyless
cloyment
cloysome
cloze test
club

WORDS THAT END LIKE CLOZAPINE

alpine
black pine
curvature of the spine
elapine
jack pine
lupine
opine
pine
porcupine
rapine
repine
reserpine
scaloppine
Scotch pine
Scots pine
spine
sugar pine
supine
vulpine
white pine

Synonyms and antonyms of clozapine in the English dictionary of synonyms

SYNONYMS

Translation of «clozapine» into 25 languages

TRANSLATOR
online translator

TRANSLATION OF CLOZAPINE

Find out the translation of clozapine to 25 languages with our English multilingual translator.
The translations of clozapine from English to other languages presented in this section have been obtained through automatic statistical translation; where the essential translation unit is the word «clozapine» in English.

Translator English - Chinese

氯氮平
1,325 millions of speakers

Translator English - Spanish

clozapina
570 millions of speakers

English

clozapine
510 millions of speakers

Translator English - Hindi

clozapine
380 millions of speakers
ar

Translator English - Arabic

كلوزابين
280 millions of speakers

Translator English - Russian

клозапин
278 millions of speakers

Translator English - Portuguese

clozapina
270 millions of speakers

Translator English - Bengali

ক্লোজাপিন
260 millions of speakers

Translator English - French

clozapine
220 millions of speakers

Translator English - Malay

Clozapine
190 millions of speakers

Translator English - German

Clozapin
180 millions of speakers

Translator English - Japanese

クロザピン
130 millions of speakers

Translator English - Korean

클로자핀
85 millions of speakers

Translator English - Javanese

Clozapine
85 millions of speakers
vi

Translator English - Vietnamese

clozapine
80 millions of speakers

Translator English - Tamil

clozapine
75 millions of speakers

Translator English - Marathi

क्लोजॅपीन
75 millions of speakers

Translator English - Turkish

klozapin
70 millions of speakers

Translator English - Italian

clozapina
65 millions of speakers

Translator English - Polish

klozapina
50 millions of speakers

Translator English - Ukrainian

клозапин
40 millions of speakers

Translator English - Romanian

clozapina
30 millions of speakers
el

Translator English - Greek

κλοζαπίνη
15 millions of speakers
af

Translator English - Afrikaans

clozapine
14 millions of speakers
sv

Translator English - Swedish

klozapin
10 millions of speakers
no

Translator English - Norwegian

klozapin
5 millions of speakers

Trends of use of clozapine

TRENDS

TENDENCIES OF USE OF THE TERM «CLOZAPINE»

The term «clozapine» is regularly used and occupies the 84.805 position in our list of most widely used terms in the English dictionary.
0
100%
FREQUENCY
Regularly used
61
/100
The map shown above gives the frequency of use of the term «clozapine» in the different countries.
Principal search tendencies and common uses of clozapine
List of principal searches undertaken by users to access our English online dictionary and most widely used expressions with the word «clozapine».

FREQUENCY OF USE OF THE TERM «CLOZAPINE» OVER TIME

The graph expresses the annual evolution of the frequency of use of the word «clozapine» during the past 500 years. Its implementation is based on analysing how often the term «clozapine» appears in digitalised printed sources in English between the year 1500 and the present day.

Examples of use in the English literature, quotes and news about clozapine

EXAMPLES

10 ENGLISH BOOKS RELATING TO «CLOZAPINE»

Discover the use of clozapine in the following bibliographical selection. Books relating to clozapine and brief extracts from same to provide context of its use in English literature.
1
Seminars in General Adult Psychiatry
Other medications taken with clozapine may present specific hazards. Other antipsychotics (especially some FGAs) also have a risk of myelosuppression, and so may increase the risk of agranulocytosis. There have been reports of respiratory ...
George Stein, Greg Wilkinson, 2007
2
The Maudsley Prescribing Guidelines
Aspiration pneumonia possibly secondary to clozapine-induced sialorrhea. J Clin Psycho- pharmacol 1996;16:462–3. 2. Praharaj SK et al. Clozapine-induced sialorrhea: pathophysiology and management strategies. Psycho- pharmacology  ...
David Taylor, Carol Paton, Robert Kerwin, 2007
3
Wyatt's Practical Psychiatric Practice, Third Edition: Forms ...
Clozapine Prescribing and Monitoring Guidelines Currently, there are three pharmaceutical companies1 that market clozapine: Novartis Pharmaceuticals, the manufacturer of Clozaril, and Mylan Laboratories and Ivax Pharmaceuticals, which ...
Richard Jed Wyatt, Robert H. Chew, 2008
4
The American Psychiatric Publishing Textbook of ...
Clozapine has played a critical role in the history of therapeutics for psychosis. When clozapine was initially developed in the 1960s (following its synthesis in 1958 in Switzerland), there was skepticism as to whether an agent that barely ...
Alan F. Schatzberg, Charles B. Nemeroff, 2009
5
Lexicon of Psychiatry, Neurology, and the Neurosciences
clozapine/jV-methyl-D-aspartate neurotoxicity clozapine overdose/hemodialysis 200 ng/mL), measures of smoking declined significantly (average decline, 25% to 35%). Patients treated at subthera- peutic CLOZ plasma levels showed no ...
Frank J. Ayd, 2000
6
American Psychiatric Association Practice Guidelines for the ...
These studies are supported by the results of a large randomized open trial, in which significantly fewer hospital readmissions were observed for patients treated with clozapine, compared to those treated with usual care in a state hospital ...
American Psychiatric Association, 2006
7
Meyler's Side Effects of Endocrine and Metabolic Drugs
Diabetes mellitus Hyperglycemia has been observed in patients taking clozapine (SEDA-26, 59). The effect of clozapine on glucose control and insulin sensitivity has been studied prospectively in 9 women and 11 men with schizophrenia ...
Jeffrey K. Aronson, 2009
8
Psychiatric Side Effects of Prescription and ...
Because of its potent antihistamine and anticholinergic effects, clozapine withdrawal typically has the appearance of rebound histaminic and cholinergic activity. Insomnia, restlessness, an increase in parkinsonism, agitation, and confusion ...
Thomas Markham Brown, Alan Stoudemire, 1998
9
Kaplan & Sadock's Concise Textbook of Clinical Psychiatry
Clozapine is a dibenzodiazepine. It is rapidly absorbed, with peak plasma levels reached in about 2 hours. Steady state is achieved in less than I week if twice- daily dosing is used. The elimination half-life is about 12 hours. Clozapine has two ...
Benjamin J. Sadock, Virginia A. Sadock, 2008
10
Side Effects of Drugs Annual: A worldwide yearly survey of ...
Kakar P, Millar-Craig M, Kamaruddin H, Burn S, Loganathan S. Clozapine induced myocarditis: a rare but fatal complication. Int J Cardiol 2006; 112(2): e5– 6. Merrill DB, Ahmari SE, Bradford JME, Lieberman JA. Myocarditis during clozapine ...
Jeffrey K Aronson, 2014

10 NEWS ITEMS WHICH INCLUDE THE TERM «CLOZAPINE»

Find out what the national and international press are talking about and how the term clozapine is used in the context of the following news items.
1
Micachu & The Shapes announce new album Good Bad Happy Sad
Now excuse me, but I gotta run and pick up my new Clozapine prescription that the doctor said would help with my humor issues. Thanks a lot ... «Tiny Mix Tapes, Jul 15»
2
What Are Neurotransmitters?
Medications used to treat schizophrenia and other mental disorders, including clozapine (Clozaril) and haloperidol (Haldol), are antagonists ... «Everyday Health, Jul 15»
3
Study: Aggressive/hyperactive kids are overprescribed powerful drugs
Antipsychotic medications like clozapine and olanzapine are used to treat schizophrenia, bipolar disorder and some symptoms of autism. «NorthJersey.com, Jul 15»
4
First-in-class therapy promising for Parkinson's disease psychosis
However studies have failed to demonstrate consistent efficacy with quetiapine and it is also limited by sedation; clozapine has efficacy but ... «ModernMedicine, Jul 15»
5
Antipsychotics Too Often Prescribed For Aggression In Children
Antipsychotic medications like clozapine and olanzapine are used to treat schizophrenia, bipolar disorder and some symptoms of autism. «NPR, Jul 15»
6
Network analysis of gene expression in mice provides new evidence …
Differential effects of haloperidol and clozapine on [(3)H]cAMP binding, protein kinase A (PKA) activity, and mRNA and protein expression of ... «Nature.com, Jun 15»
7
Clozapine-induced Stuttering Affects 1% Of Patients
A team of psychiatrists from Ireland has found that nearly 1% of patients who take the antipsychotic clozapine experience clozapine-induced ... «Mad In America, Jun 15»
8
Nurse tells Edmonton inquiry woman was in good spirits night …
Hall gave clozapine to Payne at 8:35 p.m. on Sept. 22. Hall said she is cautious when administering doses of clozapine because the prescribed ... «Edmonton Journal, Jun 15»
9
'I don't want other people to die': Inquiry begins into Alberta Hospital …
Payne was taken off her mediations and started on Clozapine shortly before her death while being cared for at Alberta Hospital's intensive care ... «Globalnews.ca, Jun 15»
10
Psychotherapists Say They Can Fix The Problems Caused By …
Up to 70% of patients with psychosis treated with antiserotoninergic second-generation antipsychotics (SGAs; clozapine, olanzapine and ... «Science 2.0, Jun 15»

REFERENCE
« EDUCALINGO. Clozapine [online]. Available <https://educalingo.com/en/dic-en/clozapine>. Apr 2024 ».
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