10 ENGLISH BOOKS RELATING TO «CYCLAZOCINE»
Discover the use of
cyclazocine in the following bibliographical selection. Books relating to
cyclazocine and brief extracts from same to provide context of its use in English literature.
in humans, it was apparent that cyclazocine produced effects that were not
produced by morphine [26]. Although cyclazocine was a potent miotic (10–15
times or more potent than morphine and nalorphine), valid potency assays of this
activity ...
2
Bulletin, Problems of Drug Dependence: Report of the ...
Of this group, 31 patients received cyclazocine and 33 patients methadone.
Fourteen of the patients (207o) were classified as high Q-score and 50 patients (
80%) as low. Excluding eight patients who had already received cyclazocine
before ...
National Research Council (U.S.). Committee on Problems of Drug Dependence, 1969
3
Report of the Thirty-sixth Annual Scientific Meeting: ...
Advantages to cyclazocine treatment. Despite the we 11- documented clinical
and statistical difficulties noted above, antagonist treatment with cyclazocine has
several clear advantages. 1. Adequate data base. As mentioned above, more ...
National Research Council (U.S.). Committee on Problems of Drug Dependence, 1974
4
Psychopharmacological Agents
Cyclazocine has a desirable duration of action (about 24hours) and good oral
activity. However, its hallucinogenic liability may prevent its acceptability and
widespread use; for example, an “induction” period of 2 weeks or longer is
required to ...
5
Technological Shortcuts to Social Change
Leon Brill, Director of the New Jersey State Narcotics Program, has noted: When
given in appropriate doses, cyclazocine reduces the subjective and physiological
effects of any morphine-like drug. When given to subjects already physically ...
Amitai Etzioni, Richard Remp, 1973
6
Drug Addiction: From Basic Research to Therapy
Cyclazocine (Fig. 15.2) is a benzomorphan originally synthesized in 1962 with
mixed κ agonist and μ antagonist activity.72 The treatment of rats with (±)-cyclazo
- cine showed a dose dependent decrease in cocaine intake with no alteration of
...
Rao S. Rapaka, Wolfgang Sadée, 2008
7
The Organic Chemistry of Drug Synthesis
The corresponding cyclopropylmethyl analogue cyclazocine (53), perhaps as a
consequence of its greater balance of antagonist activity, has proven to be quite
hallucinogenic. Omission of the phenolic group from cyclazocine results in a ...
8
Natural Products in Medicinal Chemistry
The most interesting members of the tricyclic benzomorphan series were
pentazocine (30) and cyclazocine (31) [48] (Figure 6.7). The former showed weak
antagonist activity and the latter was found to be a powerful antagonist.
Pentazocine ...
9
The Biomaterials: Silver Jubilee Compendium: Silver Jubilee ...
In the first study, composites of polyllactic acid) and labelled cyclazocine were
prepared and implanted in rats as 4 cm2 films, as ground films having particle
sizes falling within No. 25/35 sieves, and as 6.2 cm2 polyllactic acid)—
cyclazocine ...
10
ANNUAL REPORTS IN MED CHEMISTRY V9 PPR
The studies of Jasinski et al comparing cyclazocine to oxilorphan 234 showed
that oxilorphan had an oral potency about equal to that of cyclazocine and a
duration of effect at least equal to that of cyclazocine, thus projecting 24-hour
heroin ...
Richard V. Heinzelman, 1974
NEWS ITEMS WHICH INCLUDE THE TERM «CYCLAZOCINE»
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cyclazocine is used in the context of the following news items.
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... dynamisms witlessly eth organistrum unscribbled revulsed inadaptability arbusta nondynamically caseinogen cyclazocine acatastatic prattles ... «What Digital Camera, Sep 10»
