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Meaning of "cycloheximide" in the English dictionary

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DICTIONARY
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PRONUNCIATION OF CYCLOHEXIMIDE

cycloheximide  [ˌsaɪkləʊˈheksəˌmaɪd] play
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GRAMMATICAL CATEGORY OF CYCLOHEXIMIDE

noun
adjective
verb
adverb
pronoun
preposition
conjunction
determiner
exclamation
Cycloheximide is a noun.
A noun is a type of word the meaning of which determines reality. Nouns provide the names for all things: people, objects, sensations, feelings, etc.

WHAT DOES CYCLOHEXIMIDE MEAN IN ENGLISH?

Cycloheximide

Cycloheximide is an inhibitor of protein biosynthesis in eukaryotic organisms, produced by the bacterium Streptomyces griseus. Cycloheximide exerts its effect by interfering with the translocation step in protein synthesis thus blocking translational elongation. Cycloheximide is widely used in biomedical research to inhibit protein synthesis in eukaryotic cells studied in vitro. It is inexpensive and works rapidly. Its effects are rapidly reversed by simply removing it from the culture medium. Due to significant toxic side effects, including DNA damage, teratogenesis, and other reproductive effects, cycloheximide is generally used only in in vitro research applications, and is not suitable for human use as a therapeutic compound. Although it has been used as a fungicide in agricultural applications, this application is now decreasing as the health risks have become better understood. Cycloheximide is degraded by alkali, decontamination of work surfaces and containers can be achieved by washing with a non-harmful alkali solution such as soap.

Definition of cycloheximide in the English dictionary

The definition of cycloheximide in the dictionary is a toxic antibiotic that inhibits protein synthesis, used as a fungicide in agriculture.

WORDS THAT RHYME WITH CYCLOHEXIMIDE


acrylamide
əˈkrɪləˌmaɪd
anandamide
əˈnændəˌmaɪd
carbamide
ˈkɑːbəˌmaɪd
ceramide
ˈsɛrəˌmaɪd
chlorpropamide
klɔːˈprəʊpəˌmaɪd
cyanamide
saɪˈænəˌmaɪd
cyclophosphamide
ˌsaɪkləʊˈfɒsfəˌmaɪd
diamide
ˈdaɪəˌmaɪd
diethylamide
daɪˈiːθɪləˌmaɪd
dimethylformamide
daɪˌmiːθaɪlˈfɔːməˌmaɪd
formamide
ˈfɔːməˌmaɪd
frusemide
ˈfrʌsəˌmaɪd
furosemide
ˈfjʊərˌəʊsəˌmaɪd
niacinamide
ˌnaɪəˈsɪnəˌmaɪd
nicotinamide
ˌnɪkəˈtɪnəˌmaɪd
polyacrylamide
ˌpɒlɪəˈkrɪləˌmaɪd
sulfanilamide
ˌsʌlfəˈnɪləˌmaɪd
sulphonamide
sʌlˈfɒnəˌmaɪd
thalidomide
θəˈlɪdəˌmaɪd
tolbutamide
tɒlˈbjuːtəˌmaɪd

WORDS THAT BEGIN LIKE CYCLOHEXIMIDE

cyclodextrin
cyclodialysis
cyclodiene
cyclogenesis
cyclogiro
cyclograph
cyclographic
cyclohexadiene-1,4-quinone
cyclohexane
cyclohexanone
cyclohexylamine
cycloid
cycloidal
cycloidally
cycloidian
cyclolith
cyclometer
cyclometry
cyclonal
cyclone

WORDS THAT END LIKE CYCLOHEXIMIDE

acetamide
amide
bromide
calcium cyanamide
cetrimide
dibromide
ethionamide
glutethimide
hydrogen bromide
imide
indapamide
lysergic acid diethylamide
methyl bromide
polyamide
polyimide
potassium bromide
salicylamide
silver bromide
sulfacetamide
sulfonamide

Synonyms and antonyms of cycloheximide in the English dictionary of synonyms

SYNONYMS

Translation of «cycloheximide» into 25 languages

TRANSLATOR
online translator

TRANSLATION OF CYCLOHEXIMIDE

Find out the translation of cycloheximide to 25 languages with our English multilingual translator.
The translations of cycloheximide from English to other languages presented in this section have been obtained through automatic statistical translation; where the essential translation unit is the word «cycloheximide» in English.

Translator English - Chinese

放线菌酮
1,325 millions of speakers

Translator English - Spanish

cicloheximida
570 millions of speakers

English

cycloheximide
510 millions of speakers

Translator English - Hindi

cycloheximide
380 millions of speakers
ar

Translator English - Arabic

سيكلوهيكسيميد
280 millions of speakers

Translator English - Russian

циклогексимид
278 millions of speakers

Translator English - Portuguese

cicloheximida
270 millions of speakers

Translator English - Bengali

cycloheximide
260 millions of speakers

Translator English - French

cycloheximide
220 millions of speakers

Translator English - Malay

Sikloheximide
190 millions of speakers

Translator English - German

Cycloheximid
180 millions of speakers

Translator English - Japanese

シクロヘキシミド
130 millions of speakers

Translator English - Korean

사이클로 헥
85 millions of speakers

Translator English - Javanese

Sikloheximide
85 millions of speakers
vi

Translator English - Vietnamese

cycloheximide
80 millions of speakers

Translator English - Tamil

cycloheximide
75 millions of speakers

Translator English - Marathi

सायक्लोहाक्सिमइड
75 millions of speakers

Translator English - Turkish

sikloheksimid
70 millions of speakers

Translator English - Italian

cicloeximide
65 millions of speakers

Translator English - Polish

cykloheksimid
50 millions of speakers

Translator English - Ukrainian

циклогексимид
40 millions of speakers

Translator English - Romanian

cicloheximidă
30 millions of speakers
el

Translator English - Greek

κυκλοεξιμίδης
15 millions of speakers
af

Translator English - Afrikaans

cycloheximide
14 millions of speakers
sv

Translator English - Swedish

cykloheximid
10 millions of speakers
no

Translator English - Norwegian

cycloheximide
5 millions of speakers

Trends of use of cycloheximide

TRENDS

TENDENCIES OF USE OF THE TERM «CYCLOHEXIMIDE»

The term «cycloheximide» is regularly used and occupies the 77.739 position in our list of most widely used terms in the English dictionary.
0
100%
FREQUENCY
Regularly used
64
/100
The map shown above gives the frequency of use of the term «cycloheximide» in the different countries.
Principal search tendencies and common uses of cycloheximide
List of principal searches undertaken by users to access our English online dictionary and most widely used expressions with the word «cycloheximide».

FREQUENCY OF USE OF THE TERM «CYCLOHEXIMIDE» OVER TIME

The graph expresses the annual evolution of the frequency of use of the word «cycloheximide» during the past 500 years. Its implementation is based on analysing how often the term «cycloheximide» appears in digitalised printed sources in English between the year 1500 and the present day.

Examples of use in the English literature, quotes and news about cycloheximide

EXAMPLES

10 ENGLISH BOOKS RELATING TO «CYCLOHEXIMIDE»

Discover the use of cycloheximide in the following bibliographical selection. Books relating to cycloheximide and brief extracts from same to provide context of its use in English literature.
1
Handbook of Microbiological Media, Third Edition
Og K.2HP04 0.9g KH2P04 0.7g NaCl 0.2g MgSGy7H20 0.2g Yeast extract 0.14g Cycloheximide solution lO.OmL Triphenyl tetrazolium chloride solution l.OmL D- Cycloserine solution l.OmL Trimethoprin solution l.OmL Cycloheximide Solution:  ...
Ronald M. Atlas, 2004
2
Effect of water on the concentration of cycloheximide in ...
OCDEN UTAH U.S. Forest Service Research Note INT-30 1965 EFFECT OF WATER ON THE CONCENTRATION OF CYCLOHEXIMIDE IN FUEL OIL W. T. Collins and J. W. Koenigs * Division of Forest Disease and Timber Management  ...
William Thomas Collins, J. W. Koenigs, Intermountain Forest and Range Experiment Station (Ogden, Utah), 1965
3
Fungal Physiology
This nearly universal characteristic of zoopathogenic fungi has led to the widespread use of cycloheximide in selective media for their isolation. The use of cycloheximide in diagnostic test media has also been proposed [36]. Describing a ...
David H. Griffin, 1996
4
METHODS IN CELL BIOLOGY,VOLUME 12: YEAST CELLS: YEAST CELLS
analogy with the negative pleiotypic response in animal cells, cycloheximide relieves part of this inhibition by reversing the pleiotypic response. However, since ribosomal proteins cannot be made and are probably necessary for rRNA ...
David M. Prescott, 1976
5
Handbook of Media for Environmental Microbiology, Second Edition
Preparation of Medium: Add components, except cycloheximide solution and tetrazolium chloride solution, D- cycloserine solution, and trimethoprin solution to distilled/ deionized water and bring volume to 1.0L. Mix thoroughly. Adjust pH to ...
Ronald M. Atlas, 2005
6
Functional Genomics
Cycloheximide: Dissolve in water to 10 mg/mL, and store at –20°C up to several months. Protect from light. Cycloheximide is highly toxic, with an LD50 of <50 mg/ kg (see Note 2). 2. Heparin: Dissolve in water to 10 mg/mL and store at –20°C ...
Michael J. Brownstein, Arkady Khodursky, 2003
7
Integration of Modern Taxonomic Methods For Penicillium and ...
CYCLOHEXIMIDE. TOLERANCE. AS. A. TAXONOMIC. CHARACTER. IN. PENICILLIUM. Keith A. Seifert and Sabina Giuseppin, Eastern Cereal and Oilseed Research Centre, Agriculture and Agri-Food Canada, Research Branch, Ottawa, ...
Robert A. Samson, J I Pitt, 2000
8
Characterization of the Differential Susceptibility of ...
The Impact of Protein Synthesis Inhibition on the Neurochemical Responses ofNSDA, MLDA and TIP A Neurons to a Single Injection ofMPTP: Figure 4-15 demonstrates the effects of cycloheximide treatment on DA concentrations in the ME in ...
Bahareh Behrouz, 2008
9
Contributions to Thermal Physiology: Satellite Symposium of ...
Satellite Symposium of the 28th International Congress of Physiological Sciences , Pécs, Hungary, 1980 Z. Szelényi, M. Székely. at 20° or at 30°C. At 30°C, vasoconstriction due to PGE2 was abolished by cycloheximide and in two of three ...
Z. Szelényi, M. Székely, 1981
10
SV-40 Viruses: Molecular Structure: Papers
viral DNA replication could fully recover from this cycloheximide treatment and to determine what happened during this recovery period to the conversion of 255 to 215 DNA. Cycloheximide (10 ng/ml) was added to five AGMK monolayer ...
‎1973

10 NEWS ITEMS WHICH INCLUDE THE TERM «CYCLOHEXIMIDE»

Find out what the national and international press are talking about and how the term cycloheximide is used in the context of the following news items.
1
RING finger protein 31 promotes p53 degradation in breast cancer …
After 48 h, cells were treated with protein biosynthesis inhibitor (100 μM cycloheximide) for different times before whole-protein extraction. «Nature.com, Jul 15»
2
OTUB1 inhibits the ubiquitination and degradation of FOXM1 in …
Inhibition of de novo protein synthesis by cycloheximide caused a decline in FOXM1 protein levels in MCF-7 cells treated with epirubicin. «Nature.com, Jul 15»
3
Decreased LRIG1 in fulvestrant-treated luminal breast cancer cells …
Using cycloheximide (CHX) to block new protein synthesis, we found that ErbB3 protein levels decreased at time points following the addition ... «Nature.com, Jul 15»
4
BIRC5/Survivin as a target for glycolysis inhibition in high-stage …
Treatment with the translation inhibitor cycloheximide (CHX) even accelerates this effect (Figure 1d), whereas MG132, a proteasome inhibitor, ... «Nature.com, Jul 15»
5
Immunomodulatory drugs target IKZF1-IRF4-MYC axis in primary …
... of 100 μg/ml of cycloheximide (CHX) for 0, 1, 2 and 3 h, respectively. Whole-cell lysates were immunoblotted for IKZF1, CRBN and GAPDH. «Nature.com, Jun 15»
6
Role of p14ARF-HDM2-p53 axis in SOX6-mediated tumor suppression
... SOX6ΔHMG or control expression vector with cycloheximide (CHX) (100 μg/ml) treatment at 48 h post transfection for the indicated times. «Nature.com, Jun 15»
7
Prostate cancer TGF-β signalling regulator PMEPA1 halts …
... revealed that actinomycin D—a transcription inhibitor—prevented induction, but the translation inhibitor cycloheximide and inhibitors of p38, ... «Nature.com, Jun 15»
8
Kruppel-like factor 4 signals through microRNA-206 to promote …
Cells were treated with cycloheximide (Sigma) at 20 μg/ml for 24 h. Cell proliferation was determined using the ATPlite Luminescence Assay ... «Nature.com, Jun 15»
9
MDM4/HIPK2/p53 cytoplasmic assembly uncovers coordinated …
(f) HCT116 cells transfected for 48 h with GFP-HIPK2 alone (CTL) or in combination with pcDNA3.1-MDM4 and treated with cycloheximide ... «Nature.com, May 15»
10
Comparative genome analysis of Pediococcus damnosus LMG …
... supplemented with 5 ppm amphotericin B (Sigma-Aldrich) and 200 ppm cycloheximide (Sigma-Aldrich) to favor the growth of LAB and inhibit ... «BMC Blogs Network, Apr 15»

REFERENCE
« EDUCALINGO. Cycloheximide [online]. Available <https://educalingo.com/en/dic-en/cycloheximide>. Apr 2024 ».
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