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Meaning of "dedifferentiation" in the English dictionary

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DICTIONARY
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PRONUNCIATION OF DEDIFFERENTIATION

dedifferentiation  [diːˌdɪfəˌrɛnʃɪˈeɪʃən] play
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GRAMMATICAL CATEGORY OF DEDIFFERENTIATION

noun
adjective
verb
adverb
pronoun
preposition
conjunction
determiner
exclamation
Dedifferentiation is a noun.
A noun is a type of word the meaning of which determines reality. Nouns provide the names for all things: people, objects, sensations, feelings, etc.

WHAT DOES DEDIFFERENTIATION MEAN IN ENGLISH?

dedifferentiation

Cellular differentiation

In developmental biology, cellular differentiation is the process by which a less specialized cell becomes a more specialized cell type. Differentiation occurs numerous times during the development of a multicellular organism as the organism changes from a simple zygote to a complex system of tissues and cell types. Differentiation continues in adulthood as adult stem cells divide and create fully differentiated daughter cells during tissue repair and during normal cell turnover. Differentiation dramatically changes a cell's size, shape, membrane potential, metabolic activity, and responsiveness to signals. These changes are largely due to highly controlled modifications in gene expression. With a few exceptions, cellular differentiation almost never involves a change in the DNA sequence itself. Thus, different cells can have very different physical characteristics despite having the same genome. A cell that can differentiate into all cell types of the adult organism is known as pluripotent. Such cells are called embryonic stem cells in animals and meristematic cells in higher plants.

Definition of dedifferentiation in the English dictionary

The definition of dedifferentiation in the dictionary is the reversion of the cells of differentiated tissue to a less specialized form.

WORDS THAT RHYME WITH DEDIFFERENTIATION


abbreviation
əˌbriːvɪˈeɪʃən
affiliation
əˌfɪlɪˈeɪʃən
appreciation
əˌpriːʃɪˈeɪʃən
association
əˌsəʊsɪˈeɪʃən
aviation
ˌeɪvɪˈeɪʃən
depreciation
dɪˌpriːʃɪˈeɪʃən
deviation
ˌdiːvɪˈeɪʃən
differentiation
ˌdɪfəˌrɛnʃɪˈeɪʃən
humiliation
hjuːˌmɪlɪˈeɪʃən
initiation
ɪˌnɪʃɪˈeɪʃən
irradiation
ɪˌreɪdɪˈeɪʃən
mediation
ˌmiːdɪˈeɪʃən
negotiation
nɪˌɡəʊʃɪˈeɪʃən
pronunciation
prəˌnʌnsɪˈeɪʃən
radiation
ˌreɪdɪˈeɪʃən
Reconciliation
ˌrɛkənˌsɪlɪˈeɪʃən
recreation
ˌrɛkrɪˈeɪʃən
remediation
rɪˌmiːdɪˈeɪʃən
retaliation
rɪˌtælɪˈeɪʃən
variation
ˌvɛərɪˈeɪʃən

WORDS THAT BEGIN LIKE DEDIFFERENTIATION

dedicant
dedicate
dedicated
dedicatedly
dedicatee
dedication
dedicational
dedicative
dedicator
dedicatorial
dedicatory
dedifferentiate
dedimus
dedramatise
dedramatize
deduce
deducement
deducibility
deducible
deducibleness

WORDS THAT END LIKE DEDIFFERENTIATION

accreditation
action
administration
animation
application
certification
citation
combination
communication
confirmation
conversation
corporation
creation
decoration
destination
documentation
duration
education
evaluation
excitation
federation

Synonyms and antonyms of dedifferentiation in the English dictionary of synonyms

SYNONYMS

Translation of «dedifferentiation» into 25 languages

TRANSLATOR
online translator

TRANSLATION OF DEDIFFERENTIATION

Find out the translation of dedifferentiation to 25 languages with our English multilingual translator.
The translations of dedifferentiation from English to other languages presented in this section have been obtained through automatic statistical translation; where the essential translation unit is the word «dedifferentiation» in English.

Translator English - Chinese

去分化
1,325 millions of speakers

Translator English - Spanish

desdiferenciación
570 millions of speakers

English

dedifferentiation
510 millions of speakers

Translator English - Hindi

dedifferentiation
380 millions of speakers
ar

Translator English - Arabic

فقد التمايز
280 millions of speakers

Translator English - Russian

дедифференцировка
278 millions of speakers

Translator English - Portuguese

desdiferenciação
270 millions of speakers

Translator English - Bengali

dedifferentiation
260 millions of speakers

Translator English - French

dédifférenciation
220 millions of speakers

Translator English - Malay

Dedifferentiation
190 millions of speakers

Translator English - German

Entdifferenzierung
180 millions of speakers

Translator English - Japanese

脱分化
130 millions of speakers

Translator English - Korean

탈분화
85 millions of speakers

Translator English - Javanese

Dedifferentiation
85 millions of speakers
vi

Translator English - Vietnamese

dedifferentiation
80 millions of speakers

Translator English - Tamil

dedifferentiation
75 millions of speakers

Translator English - Marathi

वजाबाकी
75 millions of speakers

Translator English - Turkish

aynılaşma
70 millions of speakers

Translator English - Italian

dedifferentiation
65 millions of speakers

Translator English - Polish

odróżnicowanie
50 millions of speakers

Translator English - Ukrainian

дедифференцировка
40 millions of speakers

Translator English - Romanian

dedifferentiation
30 millions of speakers
el

Translator English - Greek

αποδιαφοροποίηση
15 millions of speakers
af

Translator English - Afrikaans

dedifferentiation
14 millions of speakers
sv

Translator English - Swedish

dedifferentiering
10 millions of speakers
no

Translator English - Norwegian

dedifferentiation
5 millions of speakers

Trends of use of dedifferentiation

TRENDS

TENDENCIES OF USE OF THE TERM «DEDIFFERENTIATION»

The term «dedifferentiation» is regularly used and occupies the 94.300 position in our list of most widely used terms in the English dictionary.
0
100%
FREQUENCY
Regularly used
56
/100
The map shown above gives the frequency of use of the term «dedifferentiation» in the different countries.
Principal search tendencies and common uses of dedifferentiation
List of principal searches undertaken by users to access our English online dictionary and most widely used expressions with the word «dedifferentiation».

FREQUENCY OF USE OF THE TERM «DEDIFFERENTIATION» OVER TIME

The graph expresses the annual evolution of the frequency of use of the word «dedifferentiation» during the past 500 years. Its implementation is based on analysing how often the term «dedifferentiation» appears in digitalised printed sources in English between the year 1500 and the present day.

Examples of use in the English literature, quotes and news about dedifferentiation

EXAMPLES

10 ENGLISH BOOKS RELATING TO «DEDIFFERENTIATION»

Discover the use of dedifferentiation in the following bibliographical selection. Books relating to dedifferentiation and brief extracts from same to provide context of its use in English literature.
1
Dedifferentiation and Redifferentiation of Renal Proximal ...
Repair of injured renal epithelium is thought to be mediated by surviving renal proximal tubular cells (RPTC) which must dedifferentiate to allow the proliferation and migration necessary for epithelial regeneration.
Mark Andrew Hallman, 2009
2
Pathology and Genetics of Tumours of Soft Tissue and Bone
ICD-O code 8858/3 Epidemiology Dedifferentiation occurs in up to 10% of well differentiated (WD) liposarcomas of any subtype, although the risk of dedifferentiation appears to be higher when dealing with deep seated ( particularly ...
Christopher D. M. Fletcher, K. Krishnan Unni, Fredrik Mertens, 2002
3
Urologic Surgical Pathology
Brawn594 reported dedifferentiation in 65% of repeat transurethral resections. Cumming and associates595 described 74 patients withrepeat transurethral resections with ameanintervalof 2.4 years; Gleason scoreremained constant in12  ...
David G. Bostwick, Liang Cheng, 2014
4
Cell Commitment and Differentiation
From embryo to adult 8.5 Dedifferentiation and redifferentiation The dedifferentiation of a fully differentiated cell and its redifferentiation into a different cell type stand in sharp contrast to the retention of stem cells that exhibit late commitment.
Norman Maclean, Brian Keith Hall, 1987
5
Comprehensive Toxicology
Although TGF- is a known potent stimulus for EMT of RPTC, its role in dedifferentiation during regeneration is not fully understood. Autocrine sigRPTC dedifferentiation regeneration has been investigated using primary RPTC cultures grown in ...
‎2010
6
Cellular Respiration and Carcinogenesis
Cellular. Respiration. and. Dedifferentiation. Roberto Scatena, Patrizia Bottoni, and Bruno Giardina Abstract Mitochondria are far more than the “powerhouse” of the cell as they have classically been described. They are also the location where ...
Shireesh Apte, Rangaprasad Sarangarajan, 2008
7
The Creativity Question
To do this, he postulates a new principle of dedifferentiation, a form of unconscious functioning that is more basic than any particular formal operation such as the mechanisms of primary process thinking.] What is common to all examples of ...
Albert Rothenberg, Carl R. Hausman, 1976
8
Stem Cell Therapy for Diabetes
Acinar cell dedifferentiation can be modulated by histone deacetylase inhibitors, such as sodium butyrate and trichostatin-A, and by the ADP-ribosylase inhibitor nicotinamide (Rooman et al., 2000), indicating that chromatin remodeling is ...
Shimon Efrat, 2009
9
Handbook of the Psychology of Aging
Dedifferentiation. in. Advanced. Old. Age. A related issue here is the possibility of changes in the factor space of the domains covered in a given longitudinal study. Considerable attention has recently been devoted to observations that ...
James E. Birren, Klaus Warner Schaie, 2001
10
Limb Regeneration
17.2.3 Dedifferentiation and retinoic acid As mentioned previously, the degree of dedifferentiation changes along the proximal-distal axis. More dedifferentiation takes place at a proximal amputation plane than at a distal plane (Ju and Kim, ...
Panagiotis A. Tsonis, 1996

10 NEWS ITEMS WHICH INCLUDE THE TERM «DEDIFFERENTIATION»

Find out what the national and international press are talking about and how the term dedifferentiation is used in the context of the following news items.
1
New technique for isolating human liver cells may help in future …
“However, detailed morphological and functional studies have demonstrated that these models are limited due to hepatocyte dedifferentiation ... «Healio, Jul 15»
2
Heat-shock factor 2 is a suppressor of prostate cancer invasion
... organoids, whereas in invasive cell types and during dedifferentiation into invasive stellate organoids, HSF2 was present in minute amounts. «Nature.com, Jun 15»
3
MYC in pancreatic cancer: novel mechanistic insights and their …
Article | PubMed |; Puri S, Folias AE, Hebrok M. Plasticity and dedifferentiation within the pancreas: development, homeostasis, and disease. «Nature.com, Jun 15»
4
Steroid induction of therapy-resistant cytokeratin-5-positive cells in …
Progestin suppression of miR-29 potentiates dedifferentiation of breast cancer cells via KLF4. Oncogene 2013; 32: 2555–2564. «Nature.com, Jun 15»
5
Dreams of a Pill to Enable Regeneration
“Our experiment shows the possibility of taking mature cells and, with addition of HIF-1a, causing dedifferentiation to a highly immature state ... «ScienceBlog.com, Jun 15»
6
A microRNA code for prostate cancer metastasis
TGF-β-enhanced activity is associated with dedifferentiation and acquisition of a stem cell-like phenotype. A number of studies have shown the ... «Nature.com, Jun 15»
7
Study demonstrates drug-induced ear tissue regeneration in mice
"Our experiment shows the possibility of taking mature cells and, with addition of HIF-1a, causing dedifferentiation to a highly immature state ... «Medical Xpress, Jun 15»
8
New Clues to a Second Genetic System
... mechanisms may allow a greater flexibility of the cell in response to environmental changes during cell differentiation and dedifferentiation.” ... «JAMA: The Journal of the American Medical Association, Jun 15»
9
Solitary fibrous tumors: loss of chimeric protein expression and …
Solitary fibrous tumor dedifferentiation is associated with the loss of chimeric oncoprotein expression, genomic instability, and cell ... «Nature.com, May 15»
10
Potentially Reversible Driver of Aging Found
They were too debilitated to handle all the dedifferentiation and differentiation. “Our model of Werner syndrome is based on the use of ESCs. «Bioscience Technology, May 15»

REFERENCE
« EDUCALINGO. Dedifferentiation [online]. Available <https://educalingo.com/en/dic-en/dedifferentiation>. Apr 2024 ».
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