10 ENGLISH BOOKS RELATING TO «DICOUMAROL»
Discover the use of
dicoumarol in the following bibliographical selection. Books relating to
dicoumarol and brief extracts from same to provide context of its use in English literature.
1
Essentials of Organic Chemistry: For Students of Pharmacy, ...
Box 1 1.3 Dicoumarol and warfarin Warfarin provides us with a slightly
incongruous state of affairs: it is used as a drug and also as a rat poison. It was
developed from a natural product, dicoumarol, and provides us with a nice
example of how ...
2
Pharmacology: Drug Actions and Reactions, Seventh Edition
Phenobarbital (60mgO.D.) L. -28 -12 0 30 60 90 120 150 180 210 Days Figure 8-
10. Effect of phenobarbital on plasma levels of dicoumarol/oiLANTiN (
bishydroxycoumarin) (•) and on prothrombin time (?) in a human subject (dose of
...
R.R. Levine, C.T. Walsh, Rochelle D. Schwartz-Bloom, 2000
3
Handbook of Pesticide Toxicology: Principles and Agents
The structure was shown to be 3,3'-methylene-bis(4-hydroxycoumarin), later
known as dicoumarol or by the trade name Dicumarol®, and it was synthetized in
April 1940. The biological synthesis during spoilage of the hay can be
rationalized ...
4
Quinones and Quinone Enzymes
The inhibitor is added to cultured cells from aqueous stock solutions that are
prepared by adding enough NaOH to allow for dissolving concentrated
dicoumarol. The same amount of vehicle is added to control cultures. HeLa cells
are treated ...
5
A Guide to Plant Poisoning of Animals in North America
dicoumarol. In one survey of 272 cured sweet clover hay samples, over one-third
contained more than 10 mg/kg of dicoumarol (range, 0 to 164.7 mg/kg).48 The
concentration of dicoumarol tends to be higher in large round bales where the
hay ...
Anthony P. Knight, Richard G. Walter, 2001
6
Advances in Daunorubicin Research and Application: 2011 ...
In this recent study, researchers in Kyoto, Japan conducted a study “To
investigate the effectiveness of a combined treatment of 3-30methylene-bis[4-
hydroxycoumarin] (dicoumarol) with doxorubicin for the treatment of urothelial
cancer, ...
7
Toxic Plants of North America
Dicoumarin, dicumarol, and dicumarin are synonyms of dicoumarol (Figures
35.103–35.106). dicoumarol prevents vitamin K regeneration and depletes its
availability Figure 35.103. Chemical structure of coumarin. Figure 35.104.
Chemical ...
George E. Burrows, Ronald J. Tyrl, 2012
8
Foreign Compound Metabolism in Mammals
change in the Michaelis constant for the turnover of dicoumarol, but a large
increase in the maximal velocity. This indicated that the enzyme responsible for
dicoumarol metabolism was qualitatively unchanged following induction with ...
Royal Society of Chemistry, D. E. Hathway, 1975
9
Antimetabolites: Advances in Research and Application: 2011 ...
Researchers detail in 'Dicoumarol enhances gemcitabine-induced cytotoxicity in
high NQOl-expressing cholangiocarcinoma cells,' new data in cholangio cancer.
In this recent study, researchers in mion Kaen, Thailand conducted a study “To ...
10
Hemolysis: New Insights for the Healthcare Professional: ...
Dicoumarol. Activates. Ca2+-permeable. Cation. Channels. Triggering.
Erythrocyte. Cell. Membrane. Scrambling. According to the authors of a study
from Tubingen, Germany, “Dicoumarol, a widely used anticoagulant, may cause
anemia, ...
9 NEWS ITEMS WHICH INCLUDE THE TERM «DICOUMAROL»
Find out what the national and international press are talking about and how the term
dicoumarol is used in the context of the following news items.
Nature is a source of many medicines
... researchers at the University of Wisconsin later identified dicoumarol in the clover as the substance that blocked production of clotting factors. «Sarasota Herald-Tribune, May 15»
Dr. Keith Roach: Nature is a source of many medicines
... researchers at the University of Wisconsin later identified dicoumarol in the clover as the substance that blocked production of clotting factors. «Herald & Review, May 15»
To Your Good Health: Nature Is a Source of Many Medicines
... researchers at the University of Wisconsin later identified dicoumarol in the clover as the substance that blocked production of clotting factors. «Valley News, May 15»
Protect livestock from sweet clover disease
Mold causes coumarin to be converted to dicoumarol, which is a potent anticoagulant. Dicoumarol also interferes with the metabolism of ... «Farm and Ranch Guide, Oct 14»
Fat-Soluble Vitamins 101
An anticoagulant called dicoumarol (chemically related to warfarin) sometimes occurs in moldy sweet clover hay or haylage. If the moldy hay is ... «TheHorse.com, Oct 14»
Northeast Michigan field crops regional report – July 25, 2013
Sweetclover contains coumarin, which can cause hemorrhaging in livestock when converted to dicoumarol by common storage fungi. Corn in ... «Michigan State University Extension, Jul 13»
How dead cattle led to the discovery of warfarin
Large-scale extraction began almost immediately, while scientists confirmed that the dicoumarol was formed when coumarin – a molecule in ... «PMLiVE, Jun 13»
Nattokinase the Natural Alternative to Harmful Prescription Blood …
This led to research into the potential use of warfarin instead of dicoumarol (a potent anticoagulant that acts by inhibiting the synthesis of ... «The Healthier Life, Jul 10»
New Anticoagulants — The Path from Discovery to Clinical Practice
Dicoumarol, a bacterial antagonist of vitamin K in spoiled sweet clover, was recognized as the agent responsible for a fatal hemorrhagic ... «New England Journal of Medicine, Jun 08»
