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Meaning of "epitope" in the English dictionary

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DICTIONARY
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PRONUNCIATION OF EPITOPE

epitope  [ˈɛpɪˌtəʊp] play
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GRAMMATICAL CATEGORY OF EPITOPE

noun
adjective
verb
adverb
pronoun
preposition
conjunction
determiner
exclamation
Epitope is a noun.
A noun is a type of word the meaning of which determines reality. Nouns provide the names for all things: people, objects, sensations, feelings, etc.

WHAT DOES EPITOPE MEAN IN ENGLISH?

Epitope

An epitope, also known as antigenic determinant, is the part of an antigen that is recognized by the immune system, specifically by antibodies, B cells, or T cells. The part of an antibody that recognizes the epitope is called a paratope. Although epitopes are usually non-self proteins, sequences derived from the host that can be recognized are also epitopes. The epitopes of protein antigens are divided into two categories, conformational epitopes and linear epitopes, based on their structure and interaction with the paratope. A conformational epitope is composed of discontinuous sections of the antigen's amino acid sequence. These epitopes interact with the paratope based on the 3-D surface features and shape or tertiary structure of the antigen. The proportion of epitopes that are conformational is unknown. By contrast, linear epitopes interact with the paratope based on their primary structure. A linear epitope is formed by a continuous sequence of amino acids from the antigen.

Definition of epitope in the English dictionary

The definition of epitope in the dictionary is the site on an antigen at which a specific antibody becomes attached.

WORDS THAT RHYME WITH EPITOPE


biotope
ˈbaɪəˌtəʊp
cope
kəʊp
dope
dəʊp
envelope
ˈɛnvəˌləʊp
grope
ɡrəʊp
hope
həʊp
isotope
ˈaɪsəˌtəʊp
metope
ˈmɛtəʊp
microscope
ˈmaɪkrəˌskəʊp
netop
ˈniːˌtəʊp
pope
pəʊp
radioisotope
ˌreɪdɪəʊˈaɪsətəʊp
rope
rəʊp
scope
skəʊp
slope
sləʊp
soap
səʊp
stope
stəʊp
taupe
təʊp
telescope
ˈtɛlɪˌskəʊp
tope
təʊp

WORDS THAT BEGIN LIKE EPITOPE

epithermal
epithesis
epithet
epithetic
epithetical
epithymetic
epitome
epitomic
epitomical
epitomisation
epitomise
epitomiser
epitomist
epitomization
epitomize
epitomizer
epitonic
epitrachelion
epitrite
epitrochoid

WORDS THAT END LIKE EPITOPE

antelope
Central Europe
Eastern Europe
electron microscope
Europe
Good Hope
gyroscope
kaleidoscope
lope
nope
ope
oscilloscope
Penelope
self-addressed envelope
self-addressed stamped envelope
stanhope
stethoscope
the rope
tightrope
trope

Synonyms and antonyms of epitope in the English dictionary of synonyms

SYNONYMS

Translation of «epitope» into 25 languages

TRANSLATOR
online translator

TRANSLATION OF EPITOPE

Find out the translation of epitope to 25 languages with our English multilingual translator.
The translations of epitope from English to other languages presented in this section have been obtained through automatic statistical translation; where the essential translation unit is the word «epitope» in English.

Translator English - Chinese

表位
1,325 millions of speakers

Translator English - Spanish

epítopo
570 millions of speakers

English

epitope
510 millions of speakers

Translator English - Hindi

मिलान
380 millions of speakers
ar

Translator English - Arabic

حاتمة
280 millions of speakers

Translator English - Russian

эпитоп
278 millions of speakers

Translator English - Portuguese

epitopo
270 millions of speakers

Translator English - Bengali

epitope
260 millions of speakers

Translator English - French

épitope
220 millions of speakers

Translator English - Malay

Epitope
190 millions of speakers

Translator English - German

Epitop
180 millions of speakers

Translator English - Japanese

エピトープ
130 millions of speakers

Translator English - Korean

에피토프
85 millions of speakers

Translator English - Javanese

Epitope
85 millions of speakers
vi

Translator English - Vietnamese

epitope
80 millions of speakers

Translator English - Tamil

எபிடோப்
75 millions of speakers

Translator English - Marathi

वर्णपट
75 millions of speakers

Translator English - Turkish

epitop
70 millions of speakers

Translator English - Italian

epitopo
65 millions of speakers

Translator English - Polish

epitopów
50 millions of speakers

Translator English - Ukrainian

епітоп
40 millions of speakers

Translator English - Romanian

epitop
30 millions of speakers
el

Translator English - Greek

επιτόπου
15 millions of speakers
af

Translator English - Afrikaans

epitoop
14 millions of speakers
sv

Translator English - Swedish

epitop
10 millions of speakers
no

Translator English - Norwegian

epitope
5 millions of speakers

Trends of use of epitope

TRENDS

TENDENCIES OF USE OF THE TERM «EPITOPE»

The term «epitope» is quite widely used and occupies the 50.441 position in our list of most widely used terms in the English dictionary.
0
100%
FREQUENCY
Quite widely used
77
/100
The map shown above gives the frequency of use of the term «epitope» in the different countries.
Principal search tendencies and common uses of epitope
List of principal searches undertaken by users to access our English online dictionary and most widely used expressions with the word «epitope».

FREQUENCY OF USE OF THE TERM «EPITOPE» OVER TIME

The graph expresses the annual evolution of the frequency of use of the word «epitope» during the past 500 years. Its implementation is based on analysing how often the term «epitope» appears in digitalised printed sources in English between the year 1500 and the present day.

Examples of use in the English literature, quotes and news about epitope

EXAMPLES

10 ENGLISH BOOKS RELATING TO «EPITOPE»

Discover the use of epitope in the following bibliographical selection. Books relating to epitope and brief extracts from same to provide context of its use in English literature.
1
Epitope Mapping Protocols
The aim of Epitope Mapping Protocols is to provide both a useful range of alternative practical methods for the experienced mapper and a fairly com prehensive introduction for someone embarking on antibody production and mapping for the ...
Glenn E. Morris, 1996
2
Epitope Recognition Since Landsteiner’s Discovery: 100 Years ...
This, in fact, is the situation with the above cited example of the A and A' epitopes that differ only by a phenylalanine-tyrosine substitution (i.e., by 1 O atom): the 2C TCR has the lowest measureable affinity for the epitope (A) that elicited target ...
M. Eibl, W.R. Mayr, G.J. Thorbecke, 2002
3
The Role of the HUIV26 Cryptic Collagen Epitope on Melanoma ...
Alexandra Cretu. Introduction During tumorigenesis, tumor and stromal cells release angiogenic growth factors and proteases that alter the structure of the ECM, thereby exposing new cryptic epitopes important in the malignant progression of ...
Alexandra Cretu, 2008
4
Genetic Techniques for Biological Research: A Case Study ...
The most common type of epitope used by molecular biologists is the peptide epitope. This is because one can easily attach such an epitope to any protein of interest using recombinant DNA technology. This is referred to as epitope tagging .
‎2002
5
Quantitative Studies in T and B Cell Epitope Mimicry
This work describes pharmaceutical aspects of some peptide vaccines based on T and B cell epitopes, from the initial computer-aided design to their synthesis, characterization, and use in mice, and finally the results of ELISA assays.
James Cavenaugh, 2009
6
Role of Epitope Valency in Tolerance and Immunity
We therefore hypothesized that epitope valency of the antigen plays a role in deciding the immune outcome. B cells are antigen presenting cells that specifically recognize antigenic epitopes and become activated in the presence of multivalent ...
Shivanee Shah, 2008
7
Methods in Plant Cell Biology
When existing molecular probes are not available or when endogenous factors interfere with detection, it may be advantageous to engineer into a transgene a short DNA sequence specifying a known polypeptide epitope (an epitope tag).
David W. Galbraith, Hans J. Bohnert, Don P. Bourque, 1995
8
Infection, Resistance, and Immunity, Second Edition
Antibodies raised to such "antigen fragments" (haptens) have provided material for the study of many aspects of antigenicity including the size of the epitope. The size of a sequential epitope may be estimated by determining the minimum size ...
Julius Kreier, 2001
9
T Cell Epitope Ontogeny in AIDS-virus Infected Cells
Jonah Bradley Sacha. RESULTS CD4+ T lymphocytes present Gag-derived epitopes early after infection To determine when SIV-derived epitopes are first presented to CD8+ T cells by MHC-I molecules on the surface of target cells, we ...
Jonah Bradley Sacha, 2007
10
Characterization of Epitope-blocking ELISA for Differential ...
CHAPTER II EVALUATION OF THE EPITOPE-BLOCKING ENZYME-LINKED IMMUNOSORBENT ASSAY FOR THE DIAGNOSIS OF WEST NILE VIRUS INFECTIONS IN HUMANS. 2.1. ABSTRACT. An epitope-blocking enzyme-linked  ...
Maria Alba Lorono Pino, 2008

10 NEWS ITEMS WHICH INCLUDE THE TERM «EPITOPE»

Find out what the national and international press are talking about and how the term epitope is used in the context of the following news items.
1
Towards an HIV vaccine
... individuals, as superinfection may provide insight to the development of a diverse Nab response with multiple epitope specificities." Besides ... «Medical Xpress, Jul 15»
2
Lucrative Penny Stocks - TapImmune (TPIV), L'Oreal (LRLCY …
... treatment of breast cancer; and Folate Receptor Alpha, a peptide epitope, which has completed Phase I human clinical trials for the treatment ... «Techsonian, Jul 15»
3
Human Memory B Cells Producing Potent Cross-Neutralizing …
... and did not bind any of the capsid proteins, suggesting that AM28 is specific for a conformation-dependent, nonlinear epitope on the virus. «Journal of Virology, Jul 15»
4
Immune response and insulin signalling alter mosquito feeding …
... of the 5′ untranslated region for morpholino binding, the full-length AsILP coding sequence, and a C-terminal V5 epitope tag for detection. «Nature.com, Jul 15»
5
Zacks Rating on Prothena Corporation plc
In addition to antibodies directed to neo-epitope targets, it is developing antibodies directed to other targets. The Company has generated ... «News Watch International, Jul 15»
6
Zacks Rating on TG Therapeutics, Inc.
TGTX-1101 (ublituximab) is a third generation monoclonal antibody that targets a epitope on the CD20 antigen found on mature B-lymphocytes ... «American Trade Journal, Jul 15»
7
Scientists May Have Found Antibody That Can Fight Deadly Dengue …
... framework of a human monoclonal antibody that strongly counteracts with a complex epitope or antigens located on the viral envelope. «Chinatopix, Jul 15»
8
Decreased LRIG1 in fulvestrant-treated luminal breast cancer cells …
We stably expressed a myc-epitope-tagged LRIG1 construct in MCF7, HCC1428 and T47D cells (Figure 3b). In addition to WT LRIG1, we also ... «Nature.com, Jul 15»
9
/THIS NEWS RELEASE IS NOT FOR DISTRIBUTION TO UNITED …
... very low levels of misfolded proteins in a biological sample: Epitope ProtectionTM and AMFIATM, an ultra-sensitive dual-bead immunoassay. «Stockhouse, Jul 15»
10
New hope for dengue vaccine
In previous research, the team created human monoclonal antibodies (HMAbs) that could bind to the antigenic section of the "epitope," or viral ... «Medical News Today, Jul 15»

REFERENCE
« EDUCALINGO. Epitope [online]. Available <https://educalingo.com/en/dic-en/epitope>. Apr 2024 ».
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