A noun is a type of word the meaning of which determines reality. Nouns provide the names for all things: people, objects, sensations, feelings, etc.
WHAT DOES GLYCOSYLATION MEAN IN ENGLISH?
Glycosylation is the reaction in which a carbohydrate, i.e. a glycosyl donor, is attached to a hydroxyl or other functional group of another molecule. In biology glycosylation mainly refers in particular to the enzymatic process that attaches glycans to proteins, lipids, or other organic molecules. This enzymatic process produces one of the fundamental biopolymers found in cells. Glycosylation is a form of co-translational and post-translational modification. Glycans serve a variety of structural and functional roles in membrane and secreted proteins. The majority of proteins synthesized in the rough ER undergo glycosylation. It is an enzyme-directed site-specific process, as opposed to the non-enzymatic chemical reaction of glycation. Glycosylation is also present in the cytoplasm and nucleus as the O-GlcNAc modification. Five classes of glycans are produced: ▪ N-linked glycans attached to a nitrogen of asparagine or arginine side-chains. N-linked glycosylation requires participation of a special lipid called dolichol phosphate.
The translations of glycosylation from English to other languages presented in this section have been obtained through automatic statistical translation; where the essential translation unit is the word «glycosylation» in English.
List of principal searches undertaken by users to access our English online dictionary and most widely used expressions with the word «glycosylation».
FREQUENCY OF USE OF THE TERM «GLYCOSYLATION» OVER TIME
The graph expresses the annual evolution of the frequency of use of the word «glycosylation» during the past 500 years. Its implementation is based on analysing how often the term «glycosylation» appears in digitalised printed sources in English between the year 1500 and the present day.
Examples of use in the English literature, quotes and news about glycosylation
10 ENGLISH BOOKS RELATING TO «GLYCOSYLATION»
Discover the use of glycosylation in the following bibliographical selection. Books relating to glycosylation and brief extracts from same to provide context of its use in English literature.
Handbook of Chemical Glycosylation: Advances in ...
Since carbohydrate oligomers are still a challenge in synthetic chemistry, this book on recent developments fulfils a great need.
Alexei V. Demchenko, 2008
additional unnatural glycosylation sites. These proteins were produced under
conditions known to reduce the rate of folding and it was shown that at some sites
there is competition between folding and glycosylation.173 Thus, variable site ...
Roslyn M. Bill, Leigh Revers, Iain Wilson, 1998
Abnormalities of IgG glycosylation and immunological disorders
Abnormalities of IgG Glycosylation and Immunological Disorders uniquely draws together the facts that have emerged to link abnormalities in IgG glycosylation and immunological disease, especially rheumatoid arthritis.
David Alan Isenberg, Thomas W. Rademacher, 1996
Glycosylation Mohamed Al-Rubeai. 2. THE EFFECT OF CELL CULTURE
PARAMETERS ON PROTEIN GLYCOSYLATION V.RESTELLI and M.BUTLER*
Department ofMicrobiology, University ofManitoba, Winnipeg, Manitoba, Canada.
Mohamed Al-Rubeai, 2002
Marks' Basic Medical Biochemistry: A Clinical Approach
DENATURATION THROUGH NONENZYMATIC MODIFICATION OF PROTEINS
Amino acids on proteins can undergo a wide range of chemical modifications that
are not catalyzed by enzymes, such as nonenzymatic glycosylation or oxidation.
Michael Lieberman, Allan D. Marks, 2009
Protein Structure and Function
From Royle, L.M. etal., unpublished. N-linked O-linked Glycosylation can change
the properties of a protein and provide recognition sites Perhaps the most
complex and diverse post-translational modifications to proteins are those that
Gregory A. Petsko, Dagmar Ringe, 2004
Exploring Genetic Mechanisms
Glycosylation Proproteins are often glycosylated at asparagine residues in the
context Asn-X- Ser(or Thr), where X can be any amino acid: N-glycosylation.
Some proproteins, for example, the precursor to human erythropoietin, may also
Maxine Singer, Paul Berg, 1997
Modeling Congenital Disorders of Glycosylation in ...
CHAPTER 2 CONGENITAL DISORDERS OF GLYCOSYLATION Protein A/-
glycosylation is an essential and pervasive event in eukaryotic development. Mild
defects in this process lead to deficiencies in cellular growth and function and are
Weston Booth Struwe, 2009
Fc Glycosylation All Igs contain N-linked oligosaccharides, and it is becoming
increasingly clear that this glycosylation plays significant roles in Ig structure and
function. Though the type and extent of glycosylation varies among isotypes, ...
William E. Paul, 2008
Inborn Metabolic Diseases: Diagnosis and Treatment
Freeze HH (2002) Human disorders in N-glycosylation and animal models.
Biochim Biophys Acta 1573:388-393 3. Jaeken J (2003) Komrower lecture:
Congenital disorders of glycosylation (CDG): it's all in it! J Inherit Metab Dis 26:99
John Fernandes, Jean-Marie Saudubray, Georges van den Berghe, 2006
10 NEWS ITEMS WHICH INCLUDE THE TERM «GLYCOSYLATION»
Find out what the national and international press are talking about and how the term glycosylation is used in the context of the following news items.
CEVEC's CAP Go derived recombinant PLAP shows superior results …
... developed cell line of CEVEC's recently introduced CAP GO technology, which provides for specifically improved glycosylation patterns. «pharmabiz.com, Jul 15»
Biobetters: The Advantages And Challenges Of Being Better
Zarxio is a small protein made in bacteria with no glycosylation (attached sugars). Biobetters, by being approved through submission of a ... «Mondaq News Alerts, Jul 15»
New Benchmark in First-to-File Submission to US FDA by Accutest …
... such as N - and C - terminal sequence, glycosylation, disulfide linking, ADCC, CDC, Ligand Binding and other Potency assays. Contact «PharmiWeb.com, Jul 15»
A new cellular target for Yersinia pestis
In addition, these manuscripts call, once again, our attention on the largely unexplored field of bacterial glycosylation, one of the new frontiers ... «Nature.com, Jun 15»
WHO further clarifies 'biological qualifier' system for naming …
... same INN, but if “a change is made in which glycosylation is found to be not comparable, then a new Greek letter and BQ would be assigned. «BioPharma-Reporter.com, Jun 15»
With the 21T, Walton hopes to see precisely what's happening, and then correlate the glycosylation modifications to key enzyme properties ... «Newswise, Jun 15»
Secretion of Fc-amidated peptide fusion proteins by Chinese …
The observed glycosylation heterogeneity illustrated for the Fc-AP-GLP1 construct (Fig. 5b) was more diverse than is typically encountered in ... «BMC Blogs Network, Jun 15»
UVA Discovers A Protein Essential To Fertilization, Bringing Us One …
Dynamic Changes in Equatorial Segment Protein 1 (SPESP1) Glycosylation During Mouse Spermiogenesis. Biology of Reproduction. 2015. «Medical Daily, Jun 15»