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Meaning of "intrinsic factor" in the English dictionary

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DICTIONARY
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PRONUNCIATION OF INTRINSIC FACTOR

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GRAMMATICAL CATEGORY OF INTRINSIC FACTOR

noun
adjective
verb
adverb
pronoun
preposition
conjunction
determiner
exclamation
Intrinsic factor is a noun.
A noun is a type of word the meaning of which determines reality. Nouns provide the names for all things: people, objects, sensations, feelings, etc.

WHAT DOES INTRINSIC FACTOR MEAN IN ENGLISH?

Intrinsic factor

Intrinsic factor, also known as gastric intrinsic factor, is a glycoprotein produced by the parietal cells of the stomach. It is necessary for the absorption of vitamin B12 later on in the small intestine. In humans, the gastric intrinsic factor protein is encoded by the GIF gene. Upon entry into the stomach, vitamin B12 becomes bound to haptocorrin, a glycoprotein. The resulting complex enters the duodenum, where pancreatic enzymes digest haptocorrin. In the less acidic environment of the small intestine, B12 can then bind to intrinsic factor. This new complex travels to the ileum, where special epithelial cells endocytose them. Inside the cell, B12 dissociates once again and binds to another protein, transcobalamin II. The new complex can exit the epithelial cells to enter the liver.

Definition of intrinsic factor in the English dictionary

The definition of intrinsic factor in the dictionary is a glycoprotein, secreted by the stomach, the presence of which is necessary for the absorption of cyanocobalamin in the intestine.

WORDS THAT BEGIN LIKE INTRINSIC FACTOR

intricacy
intricate
intricately
intricateness
intrigant
intrigante
intriguant
intriguante
intrigue
intriguer
intriguing
intriguingly
intrince
intrinsic
intrinsic semiconductor
intrinsical
intrinsicality
intrinsically
intrinsicalness
intrinsicate

WORDS THAT END LIKE INTRINSIC FACTOR

actor
benefactor
child actor
chiropractor
compactor
contactor
contractor
director
extractor
factor
growth factor
heavy-water reactor
nerve growth factor
power factor
reactor
redactor
risk factor
subcontractor
tractor
wow factor
X factor

Synonyms and antonyms of intrinsic factor in the English dictionary of synonyms

SYNONYMS

Translation of «intrinsic factor» into 25 languages

TRANSLATOR
online translator

TRANSLATION OF INTRINSIC FACTOR

Find out the translation of intrinsic factor to 25 languages with our English multilingual translator.
The translations of intrinsic factor from English to other languages presented in this section have been obtained through automatic statistical translation; where the essential translation unit is the word «intrinsic factor» in English.

Translator English - Chinese

内在因素
1,325 millions of speakers

Translator English - Spanish

factor intrínseco
570 millions of speakers

English

intrinsic factor
510 millions of speakers

Translator English - Hindi

आंतरिक कारक
380 millions of speakers
ar

Translator English - Arabic

عامل جوهري
280 millions of speakers

Translator English - Russian

внутренним фактором
278 millions of speakers

Translator English - Portuguese

fator intrínseco
270 millions of speakers

Translator English - Bengali

অভ্যন্তরীণ ফ্যাক্টর
260 millions of speakers

Translator English - French

facteur intrinsèque
220 millions of speakers

Translator English - Malay

Faktor intrinsik
190 millions of speakers

Translator English - German

Intrinsic-Faktor
180 millions of speakers

Translator English - Japanese

内因子
130 millions of speakers

Translator English - Korean

내인성 인자
85 millions of speakers

Translator English - Javanese

Faktor intrinsik
85 millions of speakers
vi

Translator English - Vietnamese

yếu tố nội tại
80 millions of speakers

Translator English - Tamil

உள்ளார்ந்த காரணி
75 millions of speakers

Translator English - Marathi

आंतरिक घटक
75 millions of speakers

Translator English - Turkish

Iç faktör
70 millions of speakers

Translator English - Italian

fattore intrinseco
65 millions of speakers

Translator English - Polish

czynnik wewnętrzny
50 millions of speakers

Translator English - Ukrainian

внутрішнім фактором
40 millions of speakers

Translator English - Romanian

factorul intrinsec
30 millions of speakers
el

Translator English - Greek

ενδογενής παράγοντας
15 millions of speakers
af

Translator English - Afrikaans

intrinsieke faktor
14 millions of speakers
sv

Translator English - Swedish

inre faktor
10 millions of speakers
no

Translator English - Norwegian

intrinsic factor
5 millions of speakers

Trends of use of intrinsic factor

TRENDS

TENDENCIES OF USE OF THE TERM «INTRINSIC FACTOR»

The term «intrinsic factor» is regularly used and occupies the 95.947 position in our list of most widely used terms in the English dictionary.
0
100%
FREQUENCY
Regularly used
55
/100
The map shown above gives the frequency of use of the term «intrinsic factor» in the different countries.
Principal search tendencies and common uses of intrinsic factor
List of principal searches undertaken by users to access our English online dictionary and most widely used expressions with the word «intrinsic factor».

FREQUENCY OF USE OF THE TERM «INTRINSIC FACTOR» OVER TIME

The graph expresses the annual evolution of the frequency of use of the word «intrinsic factor» during the past 500 years. Its implementation is based on analysing how often the term «intrinsic factor» appears in digitalised printed sources in English between the year 1500 and the present day.

Examples of use in the English literature, quotes and news about intrinsic factor

EXAMPLES

10 ENGLISH BOOKS RELATING TO «INTRINSIC FACTOR»

Discover the use of intrinsic factor in the following bibliographical selection. Books relating to intrinsic factor and brief extracts from same to provide context of its use in English literature.
1
Understanding Normal and Clinical Nutrition
Inadequate absorption typically occurs for one of two reasons: a lack of hydrochloric acid or a lack of intrinsic factor. Without hydrochloric acid, the vitamin is not released from the dietary proteins and so is not available for binding with the ...
Sharon Rady Rolfes, Kathryn Pinna, Ellie Whitney, 2011
2
Hematology: Clinical Principles and Applications
There it is freed by trypsin to bind to intrinsic factor (IF). IF is able to bind to the enterocytes of the ileum permitting Vitamin-B12 absorption into the blood. holotranscobalamin II enters the cell by endocytosis, with subsequent release of the ...
‎2007
3
Understanding Nutrition
The active forms of coenzyme B12 are methylcobalamin and deoxyadenosylcobalamin. intrinsic factor: a glycoprotein (a protein with short polysaccharide chains attached) secreted by the stomach cells that binds with vitamin B12 in the small ...
Eleanor Whitney, Sharon Rady Rolfes, 2010
4
VITAMINS AND HORMONES
As in pernicious anemia, this absorption defect can be corrected by feeding normal human gastric juice or hog intrinsic factor together with vitamin Bi2 . Because the anatomical distribution of intrinsic factor in the stomach of the rat is similar to ...
Robert Samuel Harris, Ira G. Wool, John Alexander Loraine, 1964
5
Applied Basic Science for Basic Surgical Training
Vitamin B12 binds to intrinsic factor and passes to the terminal ileum, where receptors in the ileal mucosa bind the complex and B12 is absorbed by the ileal mucosal epithelial cells. Intrinsic factor is released by the same stimuli that cause  ...
Andrew T. Raftery, 2008
6
Essentials of Immunology and Serology
breakdown in self tolerance remains elusive, the consequences of this autoimmune disorder are well documented. Because normal parietal cells secrete intrinsic factor, their destruction decreases the amount of intrinsic factor available to form ...
Jacqueline Stanley, 2002
7
Vitamins In Foods: Analysis, Bioavailability, and Stability
Gastric juice also contains two functionally distinct cobalamin-binding proteins: (1 ) haptocorrin (there are actually several haptocorrins, which are also known as R binders or cobalophilin) and (2) intrinsic factor. Haptocorrin binds a wide variety ...
George F.M. Ball, 2005
8
Differential Diagnosis in Internal Medicine: From Symptom to ...
Anti- intrinsic-factor antibodies have a high specificity. They are found in less than 1 % of healthy persons. Therefore, in spite of their poor sensitivity (only 56% of patients with pernicious anemia are positive), they are useful in the diagnostic ...
Walter Siegenthaler, 2007
9
Gastrointestinal Disease: An Endoscopic Approach
Chronic autoimmune gastritis (CAG) is thought to be caused by gastric autoimmune abnormalities, because parietal cell antibodies and/or intrinsic factor antibodies are often present. Patients with advanced cases develop a marked reduction ...
Anthony J. DiMarino, Stanley B. Benjamin, 2002
10
Nutrition in Pediatrics: Basic Science, Clinical Applications
Malabsorption can also be due to pernicious anemia, a chronic atrophic gastritis that is characterized by the presence of autoantibodies to parietal cells, which causes loss of these intrinsic factor-producing cells. Autoantibodies to intrinsic ...
Christopher Duggan, John B. Watkins, W. Allan Walker, 2008

10 NEWS ITEMS WHICH INCLUDE THE TERM «INTRINSIC FACTOR»

Find out what the national and international press are talking about and how the term intrinsic factor is used in the context of the following news items.
1
Promoting Optimal Nutrition with Digestive Enzymes - ProHealth
Importantly, the stomach also contributes a compound called intrinsic factor, which enables the absorption of vitamin B12 further downstream. «ProHealth, Jul 15»
2
Nutrient Supplements Ease Anxiety, Stress Due to Disasters
... B12, thiamine, riboflavin, folate, d-pantothenic acid, intrinsic factor, biotin, and niacin (one capsule daily); and 18 received a broad-spectrum ... «Medscape, Jul 15»
3
Athar Jaber's Defaced Sculptures Speak to Violence, Entropy, and …
... in favor of outlining common denominators across cultural time and space: violence as an intrinsic factor in human nature and time's entropic effect on matter. «ArtSlant, Jul 15»
4
General Science Bullet - Disorders in the human body - Capsule 4
In this the body fails to produce healthy red blood cells (RBCs) due to lack of vitamin B12, which arises due to absence of intrinsic factor (IF). «PaGaLGuY, Jul 15»
5
Scientists create sperm-producing female fish by turning off a single …
... and Minoru Tanaka (2015). foxl3 is a germ cell-intrinsic factor involved in sperm-egg fate decision in medaka. Science DOI:10.1126/science. «Discover Magazine, Jun 15»
6
How to avoid stomach problems
Against this background, he said a person's inherited intrinsic factor plays an important role in his health.Therefore, a man sticking to a normal ... «Economic Times, Jun 15»
7
Sperm From Ovaries
T. Nishimura et al., “foxl3 is a germ cell-intrinsic factor involved in sperm-egg fate decision in medaka,” Science, doi:10.1126/science.aaa2657, ... «The Scientist, Jun 15»
8
Taking Certain Heartburn Meds Linked To Higher Risk Of Heart Attack
Another problem with PPIs is that you they block the production of intrinsic factor, which is needed, along with extrinsic factor that you get from ... «Huffington Post, Jun 15»
9
Ticks and Lyme disease regain focus in U.S.
People near me have autoantibodies to mitochondria and anti parietal cells of stomach, which produces intrinsic factor necessary for ... «The Hoops News, May 15»
10
Emisphere Reports First Quarter 2015 Financial Results
... directly into the bloodstream even in the absence of intrinsic factor, a protein made in the stomach that normally facilitates B12 absorption. «GlobeNewswire, May 15»

REFERENCE
« EDUCALINGO. Intrinsic factor [online]. Available <https://educalingo.com/en/dic-en/intrinsic-factor>. Apr 2024 ».
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