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Meaning of "isoform" in the English dictionary

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DICTIONARY
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PRONUNCIATION OF ISOFORM

isoform  [ˈaɪsəʊˌfɔːm] play
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GRAMMATICAL CATEGORY OF ISOFORM

noun
adjective
verb
adverb
pronoun
preposition
conjunction
determiner
exclamation
Isoform is a noun.
A noun is a type of word the meaning of which determines reality. Nouns provide the names for all things: people, objects, sensations, feelings, etc.

WHAT DOES ISOFORM MEAN IN ENGLISH?

Protein isoform

A protein isoform is any of several different forms of the same protein. Different forms of a protein may be produced from very closely related gene duplicates—as 'same protein' or 'a protein' makes no sense for highly diverged paralogs that arose from a single ancestral gene that duplicated billions of years ago and subsequently diverged greatly in sequence, structure and functionality—or may arise from the same gene by alternative splicing. In older literature one can also encounter the use of the term isoform to describe alleles of the same gene, but currently the terms refers mostly to paralogous and alternatively spliced proteins, not alleles. The discovery of isoforms could explain the small number of protein coding regions genes revealed by the human genome project: different proteins encoded by the same gene could increase the diversity of the proteome. Isoforms at the DNA level are readily characterized by cDNA transcript studies.

Definition of isoform in the English dictionary

The definition of isoform in the dictionary is any of several forms of the same protein, derived either from the same gene or from different genes, each of which is similar in function to the others.

WORDS THAT RHYME WITH ISOFORM


bromoform
ˈbrəʊməˌfɔːm
chloroform
ˈklɔːrəˌfɔːm
cuneiform
ˈkjuːnɪˌfɔːm
filiform
ˈfɪlɪˌfɔːm
free-form
ˈfriːˌfɔːm
fusiform
ˈfjuːzɪˌfɔːm
glandiform
ˈɡlændɪˌfɔːm
landform
ˈlændˌfɔːm
microform
ˈmaɪkrəʊˌfɔːm
multiform
ˈmʌltɪˌfɔːm
nonuniform
ˌnɒnˈjuːnɪˌfɔːm
piriform
ˈpɪrɪˌfɔːm
planform
ˈplænˌfɔːm
plexiform
ˈplɛksɪˌfɔːm
stratiform
ˈstrætɪˌfɔːm
terraform
ˈterəˌfɔːm
thermoform
ˈθɜːməˌfɔːm
uniform
ˈjuːnɪˌfɔːm
vermiform
ˈvɜːmɪˌfɔːm
waveform
ˈweɪvˌfɔːm

WORDS THAT BEGIN LIKE ISOFORM

isodose
isodynamic
isoelectric
isoelectric point
isoelectronic
isoenzymatic
isoenzyme
isoenzymic
isoetes
isoflavone
isogamete
isogametic
isogamic
isogamous
isogamy
isogenetic
isogenic
isogenous
isogeny
isogeotherm

WORDS THAT END LIKE ISOFORM

application form
art form
booking form
conform
electroform
form
Fourier transform
free form
inform
iodoform
methyl chloroform
nitrochloroform
order form
outperform
perform
platform
reform
school uniform
sixth form
transform

Synonyms and antonyms of isoform in the English dictionary of synonyms

SYNONYMS

Translation of «isoform» into 25 languages

TRANSLATOR
online translator

TRANSLATION OF ISOFORM

Find out the translation of isoform to 25 languages with our English multilingual translator.
The translations of isoform from English to other languages presented in this section have been obtained through automatic statistical translation; where the essential translation unit is the word «isoform» in English.

Translator English - Chinese

亚型
1,325 millions of speakers

Translator English - Spanish

isoforma
570 millions of speakers

English

isoform
510 millions of speakers

Translator English - Hindi

isoform
380 millions of speakers
ar

Translator English - Arabic

شكل الإسوي
280 millions of speakers

Translator English - Russian

изоформы
278 millions of speakers

Translator English - Portuguese

isoforma
270 millions of speakers

Translator English - Bengali

isoform
260 millions of speakers

Translator English - French

isoforme
220 millions of speakers

Translator English - Malay

Isoform
190 millions of speakers

Translator English - German

Isoform
180 millions of speakers

Translator English - Japanese

イソ型
130 millions of speakers

Translator English - Korean

이소
85 millions of speakers

Translator English - Javanese

Isoform
85 millions of speakers
vi

Translator English - Vietnamese

đồng vị
80 millions of speakers

Translator English - Tamil

isoform
75 millions of speakers

Translator English - Marathi

आयसोफॉर्म
75 millions of speakers

Translator English - Turkish

izoformu
70 millions of speakers

Translator English - Italian

isoforma
65 millions of speakers

Translator English - Polish

izoformy
50 millions of speakers

Translator English - Ukrainian

ізоформи
40 millions of speakers

Translator English - Romanian

izoenzimei
30 millions of speakers
el

Translator English - Greek

ισομορφή
15 millions of speakers
af

Translator English - Afrikaans

isoform
14 millions of speakers
sv

Translator English - Swedish

isoformen
10 millions of speakers
no

Translator English - Norwegian

isoform
5 millions of speakers

Trends of use of isoform

TRENDS

TENDENCIES OF USE OF THE TERM «ISOFORM»

The term «isoform» is quite widely used and occupies the 49.320 position in our list of most widely used terms in the English dictionary.
0
100%
FREQUENCY
Quite widely used
77
/100
The map shown above gives the frequency of use of the term «isoform» in the different countries.
Principal search tendencies and common uses of isoform
List of principal searches undertaken by users to access our English online dictionary and most widely used expressions with the word «isoform».

FREQUENCY OF USE OF THE TERM «ISOFORM» OVER TIME

The graph expresses the annual evolution of the frequency of use of the word «isoform» during the past 500 years. Its implementation is based on analysing how often the term «isoform» appears in digitalised printed sources in English between the year 1500 and the present day.

Examples of use in the English literature, quotes and news about isoform

EXAMPLES

10 ENGLISH BOOKS RELATING TO «ISOFORM»

Discover the use of isoform in the following bibliographical selection. Books relating to isoform and brief extracts from same to provide context of its use in English literature.
1
Identification and Characterization of a Conserved Isoform ...
The Dorsal-related immunity factor, Dif is a Drosophilid specific transcription factor that likely arose via gene duplication of Dorsal.
Jason David Mayo, 2008
2
Regulation of Myosin II Isoform Localization and Activation ...
Insulin stimulated glucose uptake is a critical component of glucose homeostasis.
Franklin Kent Fulcher, 2006
3
Function and Regulation of NA+/H+ Exchanger Isoform 1 in ...
In conclusion, NHEI1 activity contributes to Na+ and Ca 2+ homeostasis disturbance following ischemia.
Jing Luo, 2007
4
Characterization of Human Pyruvate Dehydrogenase Kinase ...
The Q144 mutation in the R domain caused 14-fold weaker K+ binding with ATP in the Cat domain but did not alter the weaker K+ binding with ADP unless Pi was included.
Liangyan Hu, 2008
5
Structures of PKA RII Beta Holoenzymes Define Isoform Diversity
Comparison of the cAMP bound and C-subunit bound conformations of the R- subunits reveal both the dramatic conformational changes of the R- subunit upon C-subunit binding, and the isoform specific differences between the cAMP bound  ...
Simon Hugh Jolyon Brown, 2008
6
Isoform-specific Roles of Akt1 and Akt2 in Cardiac Growth ...
Akt isoform expression in WT and aktf- mice. Left, AMCMs from WT and aktl"'" mice were subjected to Akt1 , Akt2, PI-3 kinase(p1 10a), and ILK-specific immunoblotting. Right, mean immunoreactive band densitometry of scanned immunoblots ...
Brian Jesse DeBosch, 2008
7
Effects of genetic variation and aging on splice-isoform ...
Subsequently, splice-isoform ratios were assayed in both hearts and kidneys for a small number of samples. Splicing is also tightly controlled in the heart. Four of the five ratios differed significantly between the two tissues.
Jennifer L. Chisa, University of Michigan, 2006
8
International Review of Neurobiology
TABLE II (Continued) Group Protein ID p Description IPI00332838 Splice isoform 5 of basic fibroblast growth factor receptor 1 precursor 214 IPI00220631 0.95 Splice isoform 2 of ADAM 22 precursor IPI00220632 Splice isoform 3 of ADAM 22 ...
Ronald J. Bradley, R. Adron Harris, Peter Jenner, 2006
9
The Sodium Pump: Structure, Mechanism, and Regulation : ...
both T3 and DEX caused an increase in a2 isoform transcript levels similar to that observed with T3 alone. However, the T3 stimulation of a3 isoform mRNA was not observed, suggesting that DEX specifically represses the induction of a3 ...
Society of General Physiologists. Symposium, Jack H. Kaplan, Paul De Weer, 1991
10
Diagnostic and Therapeutic Advances in Hematologic Malignancies
The L-type PML-RARa isoform is expressed in approximately 55% of adult patients with APL. while the S and V isoforms are expressed in approximately 35 % and 8% of patients, respectively [65]. In the pediatric population, the V isoform  ...
Martin S. Tallman, Leo I. Gordon, 1998

10 NEWS ITEMS WHICH INCLUDE THE TERM «ISOFORM»

Find out what the national and international press are talking about and how the term isoform is used in the context of the following news items.
1
Scientists Identify New Antibody Which Could Aid in Treatment of …
Basically, the research team found that a misshapen isoform of the tau protein could develop in just 12 hours after the onset of TBI which can ... «Pioneer News, Jul 15»
2
Blood Cancer Journal - Targeting the Pim kinases in multiple myeloma
The longer 44kDa isoform of Pim-1 is derived from use of an upstream CUG start codon at nucleotides 158–160 and localizes to the plasma ... «Nature.com, Jul 15»
3
BMC Genomics | Full text | Analysis of the TGFβ-induced program in …
Among these, TP63 attenuates EMT in prostate cells [43] and alternatively spliced isoform ΔNp63α inhibits EMT in human bladder cancer cells ... «BMC Blogs Network, Jul 15»
4
BCR-signaling-induced cell death demonstrates dependency on …
Indeed, BCR stimulation-driven Bim upregulation has been attributed to a combination of transcriptional upregulation and isoform skewing, via ... «Nature.com, Jul 15»
5
New research offers potential for early intervention to prevent …
In a study published today in the online edition of the journal Nature, the researchers found that a misshapen isoform of the tau protein can ... «News-Medical.net, Jul 15»
6
Molecular genetics and pathogenesis of cardiomyopathy
Loss of desmoplakin isoform I causes early onset cardiomyopathy and heart failure in a Naxos-like syndrome. J. Med. Genet. 43, e5 (2006). «Nature.com, Jul 15»
7
Novel and recurrent CIB2 variants, associated with nonsyndromic …
CIB2 c.196C>T affects all known CIB2 protein isoforms except isoform CIB2-006 as indicated in ENSEMBL (GRCh38) and in the Genome ... «Nature.com, Jul 15»
8
Epigenetics: Disrupting histone lysine methylation
Grebien et al. suggest that this strategy may extend to cases of AML that are driven by the oncogenic p30 isoform of the transcription factor ... «Nature.com, Jul 15»
9
Insider Selling: TG Therapeutics Director Sells $290360.00 in Stock …
TGR-1202 is an orally available PI3K delta inhibitor with nanomolar potency to the delta isoform and several fold selectivity over the alpha, beta ... «WKRB News, Jul 15»
10
TG Therapeutics Director Sells $290360.00 in Stock (TGTX)
TGR-1202 is an orally available PI3K delta inhibitor with nanomolar potency to the delta isoform and several fold selectivity over the alpha, beta ... «sleekmoney, Jul 15»

REFERENCE
« EDUCALINGO. Isoform [online]. Available <https://educalingo.com/en/dic-en/isoform>. Apr 2024 ».
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