10 ENGLISH BOOKS RELATING TO «MECAMYLAMINE»
Discover the use of
mecamylamine in the following bibliographical selection. Books relating to
mecamylamine and brief extracts from same to provide context of its use in English literature.
1
Neuronal Nicotinic Receptors
(SPINKS and YOUNG 1958) and mecamylamine (STONE et al. 1956). In
particular, although mecamylamine is arguably the most widely used inhibitor of
nico- tinic receptors, accounts of the mechanism of action of mecamylamine vary
greatly.
Francesco Clementi, Diego Fornasari, Cecilia Gotti, 2000
mecamylamine hydrochloride 615 •Urge patient to report difficulty urinating,
excessive drowsiness, fever, or sore throat. •Advise patient to avoid potentially
hazardous activities until drug's CNS effects are known. • Urge patient to avoid
alcohol ...
Jones and Bartlett Publishers, 2008
3
Essential Evidence-Based Psychopharmacology
Mecamylamine is a nAchR antagonist that blocks the effect of nicotine. It has
been marketed as an antihypertensive for many years. Studies examining the
effects of short-term mecamylamine administration on smoking behavior have
shown ...
Dan Stein, Bernard Lerer, Stephen Stahl, 2012
4
Animal Models of Cognitive Impairment
Mecamylamine, administered either systemically or intrahippocampally,
increased response latency during the working- but not the reference-memory
task (Table 3.2). T-MAZE ALTERNATION Three studies have examined the
effects of ...
Edward D. Levin, Jerry J. Buccafusco, 2006
5
Nicotine Psychopharmacology
of mecamylamine pretreatment doses (0, 5, 10, 15, 20mg p.o.) prior to
generalization testing, with a different mecamylamine pretreatment dose on each
day. These mecamylamine doses were administered in ascending order across
days for ...
Jack E. Henningfield, Edythe London, Sakire Pogun, 2009
6
The Guide to Off-label Prescription Drugs: New Uses for ...
It was discovered that mecamylamine can block the rewarding effects of nicotine,
thereby reducing the urge to smoke.At high doses, mecamylamine may produce
significant adverse effects such as drowsiness,hypoten- sion,and constipation.
Kevin R. Loughlin, Joyce A. Generali, 2006
7
Clearing the Smoke: Assessing the Science Base for Tobacco ...
Mecamylamine is a nonspecific nicotinic receptor antagonist that was originally
used as an antihypertensive agent. Mecamylamine has been shown to block
many of the physiological, behavioral, and reinforcing effects of nicotine (Collins
et al.
Kathleen Stratton, Padma Shetty, Robert Wallace, 2001
8
Helping the Hard-core Smoker: A Clinician's Guide
Although the clinical efficacy of mecamylamine alone appears limited (Tennant,
Tarver, & Rawson, 1984), theoretical and empirical support for nicotine patch
plus mecamylamine treatment is growing (Rose & Levin, 1991; Rose et al.,
1994b; ...
Daniel F. Seidman, Lirio S. Covey, 1999
9
PROGRESS IN MEDICINAL CHEMISTRY
Slight activity (one-tenth that of mecamylamine) was first observed in NN-
dimethyl-t-octylamine. Then greater activity was found in N-ethyl-t-butylamine (
one-third that of mecamylamine). Finally they prepared 1,2,2,6,6-
pentamethylpiperidine ...
Gwynn Pennant Ellis, Geoffrey Buckle West, 1961
10
Tobacco or Health?: Physiological and Social Damages Caused ...
11.3.4 Mecamylamine The nicotine antagonist mecamylamine (see Sects 4.2 and
4.3.4 in Chap. 4) blocks the effects of nicotine, and hence the reward system, by
inhibiting nicotine-induced dopamine release, thus reducing the urge to smoke.
Knut-Olaf Haustein, David Groneberg, 2009
10 NEWS ITEMS WHICH INCLUDE THE TERM «MECAMYLAMINE»
Find out what the national and international press are talking about and how the term
mecamylamine is used in the context of the following news items.
Turing Pharmaceuticals Names Eliseo Salinas, MD and MSc …
... a variety of CNS indications; other current assets include Syntocinon® (oxytocin nasal solution) and Vecamyl® (mecamylamine HCl tablets). «PR Newswire, Jun 15»
What is Autonomic Dysreflexia?
Hydralazine, mecamylamine, diazoxide, and phenoxybenzamine might also be used. If an erectile dysfunction drug (e.g. Cialis, Viagra) has ... «PR Newswire, May 15»
Turing Pharmaceuticals Launches
... from Retrophin: an intranasal formulation of ketamine, Syntocinon® (oxytocin nasal solution) and Vecamyl® (mecamylamine HCl tablets). «Drug Discovery & Development, Feb 15»
Turing Pharmaceuticals Launches - Management Team Announced
... from Retrophin: an intranasal formulation of ketamine, Syntocinon® (oxytocin nasal solution) and Vecamyl® (mecamylamine HCl tablets). «Pharmaceutical Processing, Feb 15»
Retrophin Reports Third Quarter 2014 Financial Results
... Syntocinon Nasal Spray® (oxytocin), and Vecamyl® (mecamylamine HCI tablets). Under the terms of the agreement, Turing Pharmaceuticals ... «Business Wire, Nov 14»
East Coast Biotech Roundup: Raze, Retrophin, Alnylam, & More
... a deal to sell some of its non-core assets—an oxytocin nasal spray, mecamylamine HCl (Vecamyl), and ketamine—to Shkreli's new startup, ... «Xconomy, Oct 14»
Retrophin Announces Divestment of Non-Core Assets to Turing …
... and Vecamyl® (mecamylamine HCI tablets) to Turing Pharmaceuticals. Under the terms of the agreement, Turing Pharmaceuticals will pay ... «Business Wire, Oct 14»
Investor's Alert: Citigroup Inc (NYSE:C), Primoris Services Corp …
... liabilities and future milestone payments related to ketamine, Syntocinon nasal spray (oxytocin), and Vecamyl (mecamylamine HCI tablets). «Street Newswire, Oct 14»
Addex ADX71441 Positive Results in Preclinical Model of Nicotine …
The study with ADX71441 examined its effects on mecamylamine ... prior to the precipitant, mecamylamine, dose-dependently reversed the ... «MarketWatch, Jul 14»
Retrophin Completes Acquisition of Manchester Pharmaceuticals
Vecamyl® (mecamylamine HCI tablets) is indicated for the management of moderately severe to severe essential hypertension and ... «Business Wire, Mar 14»
