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Meaning of "methotrexate" in the English dictionary

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PRONUNCIATION OF METHOTREXATE

methotrexate  [ˌmɛθəʊˈtrɛkseɪt] play
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GRAMMATICAL CATEGORY OF METHOTREXATE

noun
adjective
verb
adverb
pronoun
preposition
conjunction
determiner
exclamation
Methotrexate is a noun.
A noun is a type of word the meaning of which determines reality. Nouns provide the names for all things: people, objects, sensations, feelings, etc.

WHAT DOES METHOTREXATE MEAN IN ENGLISH?

methotrexate

Methotrexate

Methotrexate /mɛθɵˈtrɛkseɪt/, abbreviated MTX and formerly known as amethopterin, is an antimetabolite and antifolate drug. It is used in treatment of cancer, autoimmune diseases, ectopic pregnancy, and for the induction of medical abortions. It acts by inhibiting the metabolism of folic acid. Methotrexate began to replace the more toxic antifolate aminopterin starting in the 1950s. The drug was originally synthesised by the Indian biochemist Yellapragada Subbarow and clinically developed by the American paediatrician Sidney Farber. It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.

Definition of methotrexate in the English dictionary

The definition of methotrexate in the dictionary is an antimetabolite drug used in the treatment of certain cancers. Formula: C20H22N8O5.

WORDS THAT RHYME WITH METHOTREXATE


ansate
ˈænseɪt
compensate
ˈkɒmpɛnˌseɪt
condensate
kənˈdɛnseɪt
decompensate
diːˈkɒmpɛnˌseɪt
decussate
dɪˈkʌseɪt
extravasate
ɪkˈstrævəˌseɪt
fissate
ˈfɪseɪt
fixate
ˈfɪkseɪt
hydrolysate
haɪˈdrɒlɪˌseɪt
insensate
ɪnˈsɛnseɪt
intensate
ɪnˈtɛnseɪt
luxate
ˈlʌkseɪt
lysate
ˈlaɪseɪt
overcompensate
ˌəʊvəˈkɒmpɛnˌseɪt
pertusate
pəˈtjuːseɪt
pulsate
pʌlˈseɪt
sate
seɪt
sensate
ˈsɛnseɪt
subluxate
sʌbˈlʌkseɪt
tergiversate
ˈtɜːdʒɪvəˌseɪt

WORDS THAT BEGIN LIKE METHOTREXATE

methodization
methodize
methodizer
methodological
methodologically
methodologies
methodologist
methodology
methods
methomania
methought
methoxide
methoxy
methoxybenzene
methoxychlor
methoxyflurane
methoxyl

WORDS THAT END LIKE METHOTREXATE

accurate
affiliate
appreciate
appropriate
associate
at any rate
certificate
chocolate
corporate
create
date
debate
donate
estate
estimate
exclusive OR gate
gate
generate
graduate
hate

Synonyms and antonyms of methotrexate in the English dictionary of synonyms

SYNONYMS

Translation of «methotrexate» into 25 languages

TRANSLATOR
online translator

TRANSLATION OF METHOTREXATE

Find out the translation of methotrexate to 25 languages with our English multilingual translator.
The translations of methotrexate from English to other languages presented in this section have been obtained through automatic statistical translation; where the essential translation unit is the word «methotrexate» in English.

Translator English - Chinese

氨甲喋呤
1,325 millions of speakers

Translator English - Spanish

metotrexato
570 millions of speakers

English

methotrexate
510 millions of speakers

Translator English - Hindi

methotrexate
380 millions of speakers
ar

Translator English - Arabic

الميثوتركسات
280 millions of speakers

Translator English - Russian

метотрексат
278 millions of speakers

Translator English - Portuguese

metotrexato
270 millions of speakers

Translator English - Bengali

মিথোট্রেক্সেট
260 millions of speakers

Translator English - French

méthotrexate
220 millions of speakers

Translator English - Malay

Methotrexate
190 millions of speakers

Translator English - German

Methotrexat
180 millions of speakers

Translator English - Japanese

メトトレキサート
130 millions of speakers

Translator English - Korean

메토트렉세이트
85 millions of speakers

Translator English - Javanese

Methotrexate
85 millions of speakers
vi

Translator English - Vietnamese

methotrexate
80 millions of speakers

Translator English - Tamil

மெத்தோட்ரெக்ஸேட்
75 millions of speakers

Translator English - Marathi

मेथोट्रेक्झेट
75 millions of speakers

Translator English - Turkish

metotreksat
70 millions of speakers

Translator English - Italian

metotressato
65 millions of speakers

Translator English - Polish

metotreksat
50 millions of speakers

Translator English - Ukrainian

метотрексат
40 millions of speakers

Translator English - Romanian

metotrexat
30 millions of speakers
el

Translator English - Greek

μεθοτρεξάτη
15 millions of speakers
af

Translator English - Afrikaans

metotreksaat
14 millions of speakers
sv

Translator English - Swedish

metotrexat
10 millions of speakers
no

Translator English - Norwegian

metotreksat
5 millions of speakers

Trends of use of methotrexate

TRENDS

TENDENCIES OF USE OF THE TERM «METHOTREXATE»

The term «methotrexate» is quite widely used and occupies the 37.482 position in our list of most widely used terms in the English dictionary.
0
100%
FREQUENCY
Quite widely used
83
/100
The map shown above gives the frequency of use of the term «methotrexate» in the different countries.
Principal search tendencies and common uses of methotrexate
List of principal searches undertaken by users to access our English online dictionary and most widely used expressions with the word «methotrexate».

FREQUENCY OF USE OF THE TERM «METHOTREXATE» OVER TIME

The graph expresses the annual evolution of the frequency of use of the word «methotrexate» during the past 500 years. Its implementation is based on analysing how often the term «methotrexate» appears in digitalised printed sources in English between the year 1500 and the present day.

Examples of use in the English literature, quotes and news about methotrexate

EXAMPLES

9 ENGLISH BOOKS RELATING TO «METHOTREXATE»

Discover the use of methotrexate in the following bibliographical selection. Books relating to methotrexate and brief extracts from same to provide context of its use in English literature.
1
Methotrexate
This book provides multidisciplinary reviews of the mechanism of action and uses of methotrexate in the treatment of cancer, psoriasis, gynecologic and inflammatory diseases.
Bruce N. Cronstein, Joseph R. Bertino, 2000
2
Binding Induced Enzyme Activated Methotrexate-alpha-peptide ...
Results from this investigation suggest that drugs conjugated to peptide ligands such as RGD may reduce the dose needed to achieve therapeutic concentrations by preferential recognition and binding to overexpressed integrin markers.
Phanidhara R. Kotamraj, 2009
3
Development of Methotrexate Prodrug by Solid Phase Peptide ...
This is also confirmed by other studies showing methotrexate amino acid prodrugs are generally weaker than the parent drug for their anti-proliferate activity. The results for MCF-7 cells are similar with caco-2 cells.
Anandkumar Shah, 2009
4
Methotrexate: Pharmacology, Clinical Uses, and Adverse Effects
In this book, the authors present topical research in the study of the pharmacology, clinical uses and adverse effects of methotrexate.
Valentina S. Castillo, Laura A. Moyano, 2012
5
Mechanisms of Methotrexate Resistance and Toxicity in ...
Thus, this thesis has convincingly established a robust non-mammalian animal model in which the mechanism of methotrexate action can be examined.
Joslynn Gayle Affleck, 2007
6
Emergency Nursing Procedures
Detailed illustrations visually reinforce techniques and clearly show steps to procedures — making this handbook an essential and comprehensive resource for any emergency professional.
Jean A. Proehl, 2008
7
Methotrexate and Hepatotoxicity in Rheamatoid Arthritis Patients
By dint of this book one can get access to know that rheumatoid arthritis leads to long term damage resulting in chronic pain, loss of function and disability but the drug Methotrexate halts the disease process and causes symptomatic ...
Shakila Parvin, 2012
8
The Efficacy and Toxicity of Methotrexate Monotherapy Versus ...
Objective. To systematically review randomized trials that compared methotrexate (MTX) monotherapy to MTX in combination with other non-biologic disease-modifying anti-rheumatic Drugs (DMARD) and to compare the performances of PubMed versus ...
Wanruchada Katchamart, 2009
9
Psoriasis
This is a concise yet thorough review of the diagnosis and treatment of many forms of psoriasis and covers current concepts in the ever-expanding field of psoriasis pathophysiology.
Alan Menter, Benjamin Stoff, 2010

10 NEWS ITEMS WHICH INCLUDE THE TERM «METHOTREXATE»

Find out what the national and international press are talking about and how the term methotrexate is used in the context of the following news items.
1
New report sheds light on the methotrexate sodium industry global …
The Methotrexate Sodium industry development trends and marketing channels are analyzed. Finally the feasibility of new investment projects ... «WhaTech, Jul 15»
2
Researchers Determine That Family History May Determine …
These patients had early-stage RA and were studied from 2000 to 2011 for response to methotrexate (MTX) and anti-TNF treatments (TNFi), ... «Healthline, Jul 15»
3
Orchestrating Key Stakeholder Engagement for Launch Success
After an accelerated FDA filing for the launch of Rasuvo (methotrexate), autoimmune disease and cancer therapy company Medac Pharma ... «Medical Marketing and Media, Jul 15»
4
Steroid-refractory chronic GVHD trial results 'overestimate' treatment …
... photopheresis, rituximab, mycophenolate mofetil, imatinib, mesenchymal stem cells, methotrexate, pentostatin, sirolimus and thalidomide. «medwireNews, Jul 15»
5
October 1 price disclosure changes announced
Methotrexate injections will see a 44.45 to 44.5% reduction, while dexamethasone corticosteroid injections will drop by 40.48% ... «Australian Journal of Pharmacy, Jul 15»
6
Scott Walker signs fetal pain abortion ban: It sets a 'reasonable …
... the baby, such as by taking Methotrexate, a drug that expels the baby. ... However, the hospital had no plan B to using Methotrexate, as no ... «Lifesite, Jul 15»
7
Methods of Anesthesia for Treating Juvenile Idiopathic Arthritis in …
In the second case, a 9-year-old girl with a 4-year history of oligoarticular JIA has been taking methotrexate for a year and now has presented ... «MD Magazine, Jul 15»
8
Metabolic syndrome in adults who received hematopoietic stem cell …
The prevention of GvHD was based on cyclosporine administration, sometimes in combination with methotrexate and/or steroids, depending on ... «Nature.com, Jul 15»
9
Homing in on targeted therapy for PAPA, PASH, PAPASH, and …
Until recently, Dr. Plewig said that clinicians relied on systemic medications such as corticosteroids, methotrexate, and other anti-inflammatory ... «ModernMedicine, Jul 15»
10
Severe RA: SB4 Biosimilar as Effective as Etanercept
... with etanercept (ETN; Enbrel, Amgen) in patients with severe rheumatoid arthritis (RA) whose disease was not controlled by methotrexate. «Medscape, Jul 15»

REFERENCE
« EDUCALINGO. Methotrexate [online]. Available <https://educalingo.com/en/dic-en/methotrexate>. Apr 2024 ».
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