10 ENGLISH BOOKS RELATING TO «METHYLATOR»
Discover the use of
methylator in the following bibliographical selection. Books relating to
methylator and brief extracts from same to provide context of its use in English literature.
1
DNA Methylation and Cancer Therapy
It would therefore be reasonable to conduct, for example, association studies for
polymorphisms in genes responsible for DNA damage repair andl or the control
of DNA methylation in subjects who develop colorectal cancer with the methylator
...
2
Guidelines for Molecular Analysis in Archive Tissues
Ogino S, Cantor M, Kawasaki T, Brahmandam M, Kirkner GJ, Weisenberger DJ,
Campan M, Laird PW, Loda M, Fuchs CS (2006) CpG island methylator
phenotype (CIMP) of colorectal cancer is best characterised by quantitative DNA
...
3
Genetics of Colorectal Cancer
“CpG island methylator phenotype (CIMP) of colorectal cancer is best
characterised by quantitative DNA methylation analysis and prospective cohort
studies.” Gut 55(7): 1000–6. Ogino, S., R. D. Odze, et al. (2006b). “Correlation of
pathologic ...
John D. Potter, Noralane M. Lindor, 2009
4
Colorectal Cancer Screening
CpG. Island. Methylator. Pathway. DNA methylation at CpG islands occurs
throughout the genome, and methylation of the gene promoter region is
associated with epigenetic silencing of gene expression. The CpG islands of the
promoter ...
Joseph Anderson, MD, Charles Kahi, MD, 2011
5
Diagnostic, Prognostic and Therapeutic Value of Gene Signatures
CpG island methylator phenotype in cancer. Nat Rev Cancer. 2004;4:988–93.
Weisenberger DJ, Siegmund KD, Campan M, et al. CpG island methylator
phenotype underlies sporadic microsatellite instability and is tightly associated
with ...
Antonio Russo, Stefano Iacobelli, Juan Iovanna, 2011
6
Textbook of Clinical Gastroenterology and Hepatology
Such tumors are said to have the CpG island methylator phenotype [6]. The exact
mechanism of the CpG island methylator phenotype is still unknown; however, it
is believed that methylation of multiple CpG sequences causes cellular ...
C. J. Hawkey, Jaime Bosch, Joel E. Richter, 2012
7
Pre-Invasive Disease: Pathogenesis and Clinical Management: ...
Toyota M, Ahuja N, Ohe-Toyota M et al (1999) CpG island methylator phenotype
in colorectal cancer. Proc Natl Acad Sci U S A 96:8681–8686 60. O'Brien MJ,
Yang S, Clebanoff JL et al (2004) Hyperplastic (serrated) polyps of the colorec-
tum: ...
Rebecca C. Fitzgerald, 2010
8
Non-Small Cell Lung Cancer: New Insights for the Healthcare ...
Data detailed in 'CpG island methylator phenotype involving chromosome 3p
confers an increased risk of non-small cell lung cancer' have been presented. “
This study aims to explore the association of CpG island methylator phenotype ...
9
Issues in Cancer Epidemiology and Research: 2011 Edition
New investigation results, 'Lymphocytic reaction to colorectal cancer is
associated with longer survival, independent of lymph node count, microsatellite
instability, and CpG island methylator phenotype,' are detailed in a study
published in ...
CpG island methylator phenotype in colorectal cancer. Proceedings of the
National Academy of Sciences USA 1999;96:8681–6. Toyota M, Ohe-Toyota M,
Ahuja N, Issa JP. Distinct genetic profiles in colorectal tumors with or without the
CpG ...
Edward P. Gelmann, Charles L. Sawyers, Frank J. Rauscher III, 2013
10 NEWS ITEMS WHICH INCLUDE THE TERM «METHYLATOR»
Find out what the national and international press are talking about and how the term
methylator is used in the context of the following news items.
DNA hypermethylation appears early and shows increased …
A general hypermethylation tendency was evaluated by two gene sets, eight CpG island methylator phenotype (CIMP) genes, and seven ... «7thSpace Interactive, Jul 15»
Different prognostic effect of CpG island methylation according to …
We have investigated the prognostic role of promoter methylation using eight CpG island methylator phenotype (CIMP) markers in 497 stage II ... «7thSpace Interactive, Jul 15»
Integrin α1β1 expression is controlled by c-MYC in colorectal cancer …
IGFBP7 is a p53-responsive gene specifically silenced in colorectal cancer with CpG island methylator phenotype. Carcinogenesis 2010; 31: ... «Nature.com, Jun 15»
NPM-ALK mediates phosphorylation of MSH2 at tyrosine 238 …
Methylator-induced, mismatch repair-dependent G2 arrest is activated through Chk1 and Chk2. Mol Biol Cell 2005; 16: 1513–1526. «Nature.com, May 15»
Altered pathways and colorectal cancer prognosis
Finally, another subgroup of tumors show the CpG island methylator phenotype (CIMP). This group overlaps with the MSI and BRAF mutated ... «BMC Blogs Network, Apr 15»
Marine Oils Lower Risk for Colorectal Cancer Subtype
This association also appeared to be independent of CpG island methylator phenotype (CIMP) and BRAF mutation status. "Our findings ... «Medscape, Mar 15»
Bringing epigenetics to the clinic
They have shown methylation of stool DNA to be a potential biomarker for colon cancer, and CpG island methylator phenotype (CIMP) to be a ... «BMC Blogs Network, Mar 15»
Video Premiere: Line & Circle, “Mesolithic”
... referred to as the glioma CpG island methylator phenotype GCIMPMedications include hydrochlorothiazide warfarin and atorvastatin. «Wondering Sound, Feb 15»
Molecular subtypes of colorectal cancer show differential survival …
... as defined by the status of four molecular markers: microsatellite instability (MSI), BRAF, KRAS, and CpG island methylator phenotype (CIMP) ... «Fred Hutch News Service, Nov 14»
Diverse brain tumor subtypes have an unanticipated common origin
Predicted evolutionary trajectory for non-glioma-CpG island methylator phenotype glioblastoma (non-GCIMP GBM). Broad copy number ... «Fred Hutchinson Cancer Research Center News, Oct 14»
