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Meaning of "RU486" in the English dictionary

Dictionary
DICTIONARY
section

PRONUNCIATION OF RU486

RU486  [ˌɑːjuːˌfɔːreɪtˈsɪks] play
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GRAMMATICAL CATEGORY OF RU486

noun
adjective
verb
adverb
pronoun
preposition
conjunction
determiner
exclamation
Ru486 is a noun.
A noun is a type of word the meaning of which determines reality. Nouns provide the names for all things: people, objects, sensations, feelings, etc.

WHAT DOES RU486 MEAN IN ENGLISH?

Mifepristone

Mifepristone is a synthetic steroid compound with both antiprogesterone and antiglucocorticoid properties. The compound is a 19-nor steroid with substitutions at positions C11 and C17, which antagonizes cortisol action competitively at the receptor level. Mifepristone is a progesterone receptor antagonist used as an abortifacient in the first months of pregnancy, and in smaller doses as an emergency contraceptive. Mifepristone is also a powerful glucocorticoid receptor antagonist, and has occasionally been used in refractory Cushing's Syndrome. During early trials, it was known as RU-38486 or simply RU-486, its designation at the Roussel Uclaf company, which designed the drug. The drug was initially made available in France, and other countries then followed—often amid controversy. It is marketed under tradenames Korlym and Mifeprex, according to FDA Orange Book. Mifepristone was the first antiprogestin to be developed and it has been evaluated extensively for its use as an abortifacient. The original target for the research group, however, was the discovery and development of compounds with antiglucocorticoid properties.

WORDS THAT RHYME WITH RU486


basics
ˈbeɪsɪks
classics
ˈklæsɪks
coccyx
ˈkɒksɪks
eighty-six
ˌeɪtɪˈsɪks
Essex
ˈɛsɪks
forensics
fəˈrɛnsɪks
kinesics
kɪˈniːsɪks
PYY3-36
ˌpiːwaɪwaɪˌθriːθɜːtɪˈsɪks
six
sɪks
Sussex
ˈsʌsɪks
Wessex
ˈwɛsɪks

WORDS THAT BEGIN LIKE RU486

RSV
RSVP
rt
Rt Hon.
Rt Rev.
Rt Revd
RTA
RTC
RTE
RTF
RTFO
RTR
RTS
RTT
RTTY
ru
ruana
Ruanda
Ruanda-Urundi

Synonyms and antonyms of RU486 in the English dictionary of synonyms

SYNONYMS

Translation of «RU486» into 25 languages

TRANSLATOR
online translator

TRANSLATION OF RU486

Find out the translation of RU486 to 25 languages with our English multilingual translator.
The translations of RU486 from English to other languages presented in this section have been obtained through automatic statistical translation; where the essential translation unit is the word «RU486» in English.

Translator English - Chinese

RU486
1,325 millions of speakers

Translator English - Spanish

RU486
570 millions of speakers

English

RU486
510 millions of speakers

Translator English - Hindi

RU486
380 millions of speakers
ar

Translator English - Arabic

RU486
280 millions of speakers

Translator English - Russian

RU486
278 millions of speakers

Translator English - Portuguese

RU486
270 millions of speakers

Translator English - Bengali

RU486
260 millions of speakers

Translator English - French

RU486
220 millions of speakers

Translator English - Malay

RU486
190 millions of speakers

Translator English - German

RU486
180 millions of speakers

Translator English - Japanese

RU486
130 millions of speakers

Translator English - Korean

RU486
85 millions of speakers

Translator English - Javanese

RU486
85 millions of speakers
vi

Translator English - Vietnamese

RU486
80 millions of speakers

Translator English - Tamil

RU486
75 millions of speakers

Translator English - Marathi

RU486
75 millions of speakers

Translator English - Turkish

RU486
70 millions of speakers

Translator English - Italian

RU486
65 millions of speakers

Translator English - Polish

RU486
50 millions of speakers

Translator English - Ukrainian

RU486
40 millions of speakers

Translator English - Romanian

RU486
30 millions of speakers
el

Translator English - Greek

RU486
15 millions of speakers
af

Translator English - Afrikaans

RU486
14 millions of speakers
sv

Translator English - Swedish

RU486
10 millions of speakers
no

Translator English - Norwegian

RU486
5 millions of speakers

Trends of use of RU486

TRENDS

TENDENCIES OF USE OF THE TERM «RU486»

The term «RU486» is normally little used and occupies the 117.618 position in our list of most widely used terms in the English dictionary.
0
100%
FREQUENCY
Little used
45
/100
The map shown above gives the frequency of use of the term «RU486» in the different countries.
Principal search tendencies and common uses of RU486
List of principal searches undertaken by users to access our English online dictionary and most widely used expressions with the word «RU486».

FREQUENCY OF USE OF THE TERM «RU486» OVER TIME

The graph expresses the annual evolution of the frequency of use of the word «RU486» during the past 500 years. Its implementation is based on analysing how often the term «RU486» appears in digitalised printed sources in English between the year 1500 and the present day.

Examples of use in the English literature, quotes and news about RU486

EXAMPLES

10 ENGLISH BOOKS RELATING TO «RU486»

Discover the use of RU486 in the following bibliographical selection. Books relating to RU486 and brief extracts from same to provide context of its use in English literature.
1
Clinical Applications of Mifepristone (RU486) and Other ...
This book provides an unbiased evaluation of current knowledge about both the fundamental nature of antiprogestins as well as their possible use in treating numerous diseases and conditions, and it contains recommendations for future ...
Leslie Z. Benet, Molla S. Donaldson, 1993
2
Progestins and the Mammary Gland: From Basic Science to ...
observed because RU486 appears to function as an agonist (Gravanis et al. 1985). In summary, RU486 has temporal PR regulatory activity depending on the duration of RU486 treatment. But the temporal regulation of PR activity by RU486 is ...
Orla M. Conneely, Christiane Otto, 2008
3
Modulation of the Neonatal T Cell-mediated Immune Response ...
The type II glucocorticoid receptor antagonist RU486 is transferred from mother to neonate via the milk. We had previously demonstrated that maternally derived corticosterone is not only readily transferred to the neonate via the milk but also ...
Hassan Zahwa, 2008
4
RU-486: The Abortion Pill
tHe. HIstoRy. oF. RU486. In. eURope. And. tHe. UnIted. stAtes. The history of the development of the drug, from the laboratory in France to commercial availability, is a story of intrigue, plot and counter plot. Unsurprisingly, from the time of the ...
Caroline De Costa, 2007
5
Regulatory Mechanisms in Transcriptional Signaling
... stimulates proliferation of leiomyoma cells.112–116 Progesterone markedly increased BCL2 protein expression in primary leiomyoma cell cultures.112–116 Clinical studies with both progestins and RU486 indicate that progesterone may be ...
‎2009
6
Effect of Ru486, a Progesterone Antagonist, on Uterine ...
These works are packaged and produced by BiblioLabs under license by ProQuest UMI.
Daniel J. Mathew, 2012
7
Methods in Pain Research
A target construct contained four hPR binding sites as well as a liver-specific promoter.28,29 This system also demonstrated extremely low basal activity and robust expression upon induction with RU486. Dose-dependent amounts of ...
Lawrence Kruger, 2001
8
Neuroplasticity, Development, and Steroid Hormone Action
Recently, our lab has re-examined this question by blocking endogenous progesterone action in the neonate with the PR antagonist mifepristone (RU486). Neonatal males received RU486 treatment from the day of birth through postnatal day ...
Robert J. Handa, Shinji Hayashi, Ei Terasawa, 2001
9
Pregnancy and Parturition
RU486 is a potent 19-norsteroid synthetic progesterone receptor antagonist. Administration of RU486 antagonizes progesterone and results in the induction of labor at any time during gestation in women as well as rhesus monkeys. Haluska ...
T. Zakar, 1996
10
Nonviral Vectors for Gene Therapy
DNA binding sites should render our inducible system useful for most biological applications. Furthermore, using RU486 as an inducer is highly advantageous because of the following: (1) rapid delivery to cells, (2) good penetration into cells , ...
Mien-Chie Hung, Leaf Huang, Ernst Wagner, 1999

10 NEWS ITEMS WHICH INCLUDE THE TERM «RU486»

Find out what the national and international press are talking about and how the term RU486 is used in the context of the following news items.
1
Arkansas passes standards overseeing RU486 abortions
Arkansas becomes the latest state to order that abortionists must follow Food and Drug Administration standards for RU486 abortions. The law includes a ban on ... «OneNewsNow, Mar 15»
2
Darwin mother speaks out about surgical abortion amid RU486
Overall, she said being able to terminate her pregnancy earlier in gestation using RU486 would have made "the whole process easier to deal with". "I would ... «ABC Local, Jan 15»
3
Arizona wins, Planned Parenthood loses, over use of RU486
Arizona has won round one against Planned Parenthood over legal use of the abortion drug RU486 is used, but it's not the end of the battle. Arizona lawmakers ... «OneNewsNow, Apr 14»
4
Why the $12 abortion pill RU486 costs Australian women $500
With an estimated failure rate of up to 10 per cent for RU486, a second ultrasound is required a week after the procedure to ensure the woman doesn't require a ... «The Daily Telegraph, Dec 13»
5
RU486 is not the 'safe' DIY method for women it is claimed to be
Recent publicity for abortion drug RU486 has given women assurances of its safety. The drug is promoted as do-it-yourself, easy, private and ''more natural''. «Brisbane Times, Aug 13»
6
Finally , greater access to RU486 – now let's collect abortion data
Medical abortions will finally be easily available to Australian women when the drug RU486 (mifepristone and misoprostol) is listed on the Pharmaceutical ... «The Conversation, Jul 13»
7
Abortion pill RU486 and three cancer drugs added to the …
Abortion pill RU486 and three cancer drugs have been subsidised, with the Federal Government adding them to the Pharmaceutical Benefits Scheme (PBS). «ABC Online, Jun 13»
8
Pharmacist threatens to quit over RU486
A pharmacy owner says he will walk away from the profession if pharmacists are required to dispense abortion drugs Mifepristone (RU486) and Misoprstol. «Pharmacy News, May 13»
9
The decision to recommend PBS listing for RU486 is a significant …
Below they provide insight into the implications of last week's important decision to recommend PBS listing for RU486. The decision, announced last Friday by ... «Crikey, Apr 13»
10
RU486 hits Abbott - again
The government has signalled that it wants to put the abortion drug RU486 on the Pharmaceutical Benefits list. It is beginning the process of negotiating over ... «The Conversation, Apr 13»

REFERENCE
« EDUCALINGO. Ru486 [online]. Available <https://educalingo.com/en/dic-en/ru486>. Oct 2020 ».
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