The adjective is the word that accompanies the noun to determine or qualify it.
WHAT DOES SENESCENT MEAN IN ENGLISH?
Senescence or biological aging is the gradual deterioration of function characteristic of most complex lifeforms, arguably found in all biological kingdoms, that on the level of the organism increases mortality after maturation. The word "senescence" can refer either to cellular senescence or to senescence of the whole organism. It is commonly believed that cellular senescence underlies organismal senescence. The science of biological aging is biogerontology. Senescence is not the inevitable fate of all organisms. Organisms of some taxonomic groups, including some animals, even experience chronological decrease in mortality, for all or part of their life cycle. On the other extreme are accelerated aging diseases, rare in humans. There is also the extremely rare and poorly understood "Syndrome X", whereby a person remains physically and mentally an infant or child throughout one's life. Even if environmental factors do not cause aging, they may affect it; in such a way, for example, overexposure to ultraviolet radiation accelerates skin aging. Different parts of the body may age at different rates.
The translations of senescent from English to other languages presented in this section have been obtained through automatic statistical translation; where the essential translation unit is the word «senescent» in English.
List of principal searches undertaken by users to access our English online dictionary and most widely used expressions with the word «senescent».
FREQUENCY OF USE OF THE TERM «SENESCENT» OVER TIME
The graph expresses the annual evolution of the frequency of use of the word «senescent» during the past 500 years. Its implementation is based on analysing how often the term «senescent» appears in digitalised printed sources in English between the year 1500 and the present day.
Examples of use in the English literature, quotes and news about senescent
QUOTES WITH «SENESCENT»
Famous quotes and sentences with the word senescent.
The world does not get to be a better or a worse place; it just gets more senescent.
10 ENGLISH BOOKS RELATING TO «SENESCENT»
Discover the use of senescent in the following bibliographical selection. Books relating to senescent and brief extracts from same to provide context of its use in English literature.
Age Rage and Going Gently: Stories of the Senescent Subject ...
It espouses a critical interdisciplinarity and calls into question the assumptions underlying much research into ageing in the social sciences, work in which the negative aspects of growing older are almost invariably suppressed.
Oliver Davis, 2006
Anxiety and Preoperative Education in the Senescent Patient
This study will focus on preoperative education for the senescent adult as it
relates to anxiety before and after the education process to determine the extent
to which providing this education will alter anxiety in this population. Simply
Tal R. Sutton, 2007
Principles and Practice of Geriatric Surgery
In fact, a persistent DDR and elevated intracellular ROS production appear to
play a critical role not only in the induction of the senescent phenotype but also in
its maintenance [279, 281]. Products of the retinoblastoma (Rb) and p53 tumor ...
Ronnie Ann Rosenthal, Michael E. Zenilman, Mark R. Katlic, 2011
The concept of senescent alopecia evolved from clinical observations that diffuse
hair thinning involving the whole scalp may develop after the age of 50 years in
people with no family history of balding. Scalp surface studies favored the idea ...
Ralph M. Trüeb, Desmond Tobin, 2010
Aging and Age-related Diseases: The Basics
It is difficult to know the extent to which the senescent states are induced by the
ep53 and pRB pathways are distinct or similar. In addition, depending on the
tissue and species of origin, cells may differ in both their senescent phenotype
Micha Karasek, 2006
Textbook of Aging Skin
pathways identified in cellular senescence involve p53, p16, p21 and pRB .
There is compelling evidence suggesting that senescent cells accumulate in
aged tissues [71–73]. In order to assess the contribution of senescent cells to
Miranda A. Farage, Kenneth W. Miller, Howard I. Maibach, 2010
Cells, Aging, and Human Disease
This is more difficult than counting population doublings, though also more
rewarding experimentally, theoretically, and clinically. Orthogonally to the
problem of measuring senescence is the problem of agreeing to a cutoff: how
senescent is ...
Michael B. Fossel M.D. Clinical Professor of Medicine Michigan State University, 2004
Biological Aging: Methods and Protocols
accumulation of senescent cells in aged tissues is also thought to contribute to
age-related pathologies (3). It is generally accepted that human fibroblasts and
other cell types senesce after repeated cell division because they eventually ...
Trygve O. Tollefsbol, 2007
Tumor Dormancy, Quiescence, and Senescence, Volume 1: Aging, ...
Senescent cells can affect their microenvironment in multiple ways. The influence
of SASP components is not restricted to the ECM or to cells in their immediate
microenvironment. Several of these components are potent proinflammatory ...
M.A. Hayat, 2013
New Research on Cell Aging
Cells that demonstrated apoptosis after nocodazole treatment, however, greatly
decreased in later passages suggesting dysfunction of mitotic checkpoint in
senescent cells. The observations in this study suggest that the mitotic failure
Reginald B. Garvey, 2007
10 NEWS ITEMS WHICH INCLUDE THE TERM «SENESCENT»
Find out what the national and international press are talking about and how the term senescent is used in the context of the following news items.
Cell signalling Limiting the side effects of senescence
The SASP is a major feature of senescent cells and involves the secretion of cytokines, growth factors and proteases. Cellular senescence, which is a state of ... «Nature.com, Jul 15»
Post-Senescent Stage of Advanced Capitalism; EU and Greece
One mark of the post-senescent stage of advanced capitalism is that traditional imperialist concerns of markets, investments, raw materials ownership and ... «CounterPunch, Jul 15»
Protein in metabolic reprogramming restrains senescent cells from …
Shown on the left is an ATM positive cell that has undergone senescence (depicted by blue color). On the right are cells with low ATM that are not senescent due ... «Medical Xpress, Apr 15»
Cell senescence Communicating with senescence
Senescent cells secrete molecules to communicate with surrounding cells. Biran et al. report that communication can also occur by intercellular protein transfer ... «Nature.com, Apr 15»
SIWA's Approach To Clearing Senescent Cells To Increase …
The results of the work performed by Charles River for SIWA include an increase in gastrocnemius muscle mass and reduction of a senescent cell mRNA marker ... «PR Web, Mar 15»
New range of drugs may slow ageing process by taking out …
Their research focuses on so-called senescent cells - cells we acquire throughout life that shut down, stop dividing and sit there making few useful contributions ... «South China Morning Post, Mar 15»
A True Fountain-Of-Youth Drug Combo?
Most of them do, but some cells become senescent: old geezers who just won't go away. The problem is, these cells just don't sit quietly in the living room ... «Forbes, Mar 15»
Kill Senescent Cells Before They Kill You
Researchers searched for ways to eliminate cells in the body that have become senescent and destructive. Their tests in cell cultures and in genetically-modified ... «ScienceBlog.com, Mar 15»
New class of drugs reduces aging in mice, Mayo Clinic study finds
The study found two drugs that were especially good at getting rid of senescent cells. These are cells that have ceased to reproduce through division but also ... «Washington Post, Mar 15»
Senescent cells play an essential role in wound healing
Senescent cells have a bad-guy reputation when it comes to aging. While cellular senescence - a process whereby cells permanently lose the ability to divide ... «EurekAlert, Dec 14»
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