10 ENGLISH BOOKS RELATING TO «URICOSURIC»
Discover the use of
uricosuric in the following bibliographical selection. Books relating to
uricosuric and brief extracts from same to provide context of its use in English literature.
1
ADVANCES IN PHARMACOLOGY
Uricosuric Drugs, with Special Reference to Probenecid and Sulfinpyrazone*
ALEXANDER B. GUTMAN Department of Medicine, The Mount Sinai Hospital,
New York, New York . Uricosuric Activity Defined . . . . . . . . Physiological Basis for
Use ...
Silvio Garattini, Parkhurst A. Shore, 1966
Which patients with recurrent gouty arthritis are candidates for uricosuric therapy
? • Hyperuricemia secondary to underexcretion of uric acid (< 700 mg of uric acid
in a 24- hour urine collection, while on a regular diet) • Age < 60 yrs • Creatinine ...
3
Beating Gout: A Sufferer's Guide to Living Pain Free
It's recommended that people with a history of kidney problems, kidney stones or
who are over age 60 should not use uricosuric drugs.19 Your doctor also will
want to check your kidney function before starting you on uricosuric drugs to
make ...
4
Drug Discovery and Evaluation: Pharmacological Assays
Hans Vogel. Dan T, Yoneya T, Onoma M, Onuma E, Ozawa K (1994) Hy-
pouricemic and uricosuric actions of AA-193 in a hyper- uricemic rat model.
Metabolism 43:123-128 Hropot M, Sorgel F, v Kerekjarto B, Lang HJ,
Muschaweck R (1980) ...
5
Primer on the Rheumatic Diseases
The molecular target for uricosuric agents, an anion exchanger responsible for
the reabsorption of filtered urate by the renal proximal tubule, was identified
recently (1,11). The authors searched the human genome database for novel
gene ...
John H. Klippel, John H. Stone, L eslie J. Crofford, 2008
6
Drug Therapy in Nursing
CHAPTER. Drugs. Treating. Rheumatoid. Arthritis. and. Gout. Learning
Objectives At the completion of this chapter the student will: 1 . Correlate the
processes of inflammation and pain with antirheumatic drugs, antigout drugs, and
uricosuric ...
Diane S. Aschenbrenner, Samantha J. Venable, 2009
7
Antihypertensive Drugs Today
Studies on uricosuric diuretics. 1) 6,7-Dichloro-5-sulfamoyl-2,3-
dihydrobenzofuran-2-carboxylic acids. Chem. Pharm. Bull. 35 (8), 3195-3214.
Harada, H., Matsushita, Y., Yodo, M., Nakamura, M. and Yonetani, Y. (1987b).
Studies on uricosuric ...
Hideya Saitō, Masaru Minami, 1992
8
Gout and Other Crystal Arthropathies
l Inefficient renal excretion of uric acid is the most common cause of
hyperuricemia in gout patients. l Uricosuric drugs tend to normalize renal
excretion of uric acid through inhibiting renal tubular reabsorption of uric acid,
thus reducing serum ...
9
Modern Pharmacology with Clinical Applications
Uricosuric drugs at appropriate doses interfere with these processes. CASE
Study Injudicious Food Intake Can Lead to Pain sophils. Peritubular Capillary
Proximal Tubule Cell inhibited by uricosuric drugs (high doses) Proximal Tubule
Lumen ...
Charles R. Craig, Robert E. Stitzel, 2004
10
Evidence-Based Rheumatology
Question 13 Should we be using uricosuric drugs or xanthine oxidase inhibitors?
The two main classes of drugs used to treat chronic gout are the uricosuric drugs
and the xanthine oxidase blockers. In a survey of prescribing practices in ...
Peter Tugwell, Beverley Shea, Maarten Boers, 2009
10 NEWS ITEMS WHICH INCLUDE THE TERM «URICOSURIC»
Find out what the national and international press are talking about and how the term
uricosuric is used in the context of the following news items.
CymaBay (CBAY) Phase 2 Data for Arhalofenate in Combination …
It lowers serum uric acid by a uricosuric effect and also has an anti-inflammatory activity that suppresses flares. It is the first compound in a new class of gout ... «StreetInsider.com, Jun 15»
CymaBay Therapeutics' (CBAY) CEO Hal Van Wart on Q1 2015 …
First, to lower serum uric acid with a uricosuric action that increases the excretion of uric acid into urine. Second, it blocks the urate crystal induced production of ... «Seeking Alpha, May 15»
CymaBay Therapeutics' (CBAY) CEO Harold Van Wart on Q4 2014 …
A second important result from this study was the demonstration that the serum uric acid lowering contributed by the uricosuric activity of arhalofenate was ... «Seeking Alpha, Mar 15»
New Genetic Clues to Gout Susceptibility
... allopurinol and febuxostat, while patients with risk alleles for RUE-type gout would be administered uricosuric agents including benzbromarone and lesinurad, ... «MedPage Today, Feb 15»
Cymabay Therapeutics Announces Positive Results From Its Phase …
This leads to the excretion of uric acid into the urine (a uricosuric effect) that could ... have been collected to understand the time course of the uricosuric effect. «MarketWatch, Jan 15»
Reconsidering Allopurinol for Hypertension
This also is seen with uricosuric agents, so is it just lowering of the uric acid level or is there something special about what allopurinol and similar drugs do? «Medscape, Jan 15»
Adding Lesinurad May Lower Uric Acid
... MD, PhD at the Cleveland Clinic, The long-term renal safety of a potent uricosuric agent with respect to nephrolithiasis and interstitial renal function remains to ... «MedPage Today, Dec 14»
Daryl Impey: a very unusual case
While probenecid has been described as a diuretic, it actually is a 'uricosuric' drug that increases the urinary excretion of uric acid, which causes gout. «SPORT24, Sep 14»
Uricosuric Drugs: The Once and Future Therapy for Hyperuricemia?
Purpose of review: Although uricosuric agents provide the most time-honoured approach to the control of hyperuricemia, their place in the armamentarium has ... «Medscape, Jun 14»
After burning up $349M, CymaBay aims for Nasdaq as IPOs get shaky
The lead drug, dubbed arhalofenate, is an anti-inflammatory uricosuric therapy designed to reduce the risk of painful gout flareups. The biotech also has ... «FierceBiotech, Apr 14»
