Meaning of "エーディーエー‐けっそんしょう" in the Japanese dictionary

PRONUNCIATION OF エーディーエー‐けっそんしょう IN JAPANESE

えーでぃー	えー
エーディー	エー	‐	けっ	そん	しょ	う
e-dhi-	e-		kextu	son	syo	u

WHAT DOES エーディーエー‐けっそんしょう MEAN IN JAPANESE?

Definition of エーディーエー‐けっそんしょう in the Japanese dictionary

ADA deficiency diseases that cause severe immunodeficiency because they can not produce an enzyme called adenosine deaminase (ADA) in the body. It occurs because the gene synthesizing ADA is inherently defective or mutated. The number of lymphocytes is extremely small, and unless treatment is carried out, in many cases it dies due to infection etc. in infancy. Conventional enzyme replacement therapy that supplements ADA needs to last a lifetime, and medical expenses also become expensive. In recent years, gene therapy has been carried out in which ADA gene is incorporated into a vector and introduced into lymphocytes, and certain effects are raised. [Supplementary] In Japan, in 1995, gene therapy for ADA deficiency was performed for the first time at Hokkaido University. Since the survival time of lymphocytes is limited, gene therapy is underway that enables ADA to be produced throughout life by introducing ADA gene into bone marrow stem cells.

エーディーエー‐けっそんしょう【ADA欠損症】 体内でアデノシンデアミナーゼ（ADA）という酵素を作り出せないために重度の免疫不全になる病気。ADAを合成する遺伝子が先天的に欠損または変異しているために起こる。リンパ球の数が極度に少なく、治療を行わないと乳幼児期に感染症などで死亡することが多い。ADAを補充する従来の酵素補充療法は一生継続する必要があり、療養費も高額になる。近年、ADA遺伝子をベクターに組み込んでリンパ球に導入する遺伝子治療が行われるようになり、一定の効果をあげている。 [補説]日本では平成7年（1995）に北海道大学で初めてADA欠損症の遺伝子治療が行われた。リンパ球の生存期間は限られているため、骨髄幹細胞にADA遺伝子を導入することで生涯にわたってADAを作り出せるようにする遺伝子治療が行われている。

TRANSLATION OF エーディーエー‐けっそんしょう

Find out the translation of エーディーエー‐けっそんしょう to 25 languages with our Japanese multilingual translator.

The translations of エーディーエー‐けっそんしょう from Japanese to other languages presented in this section have been obtained through automatic statistical translation; where the essential translation unit is the word «エーディーエー‐けっそんしょう» in Japanese.

• Translator Japanese - Chinese: 你将无法获得伊迪
• Translator Japanese - Spanish: Vas a Edie indisponibilidad
• Translator Japanese - English: You´ll Edie unavailability
• Translator Japanese - Hindi: आप एडी अनुपलब्धता हूँ
• Translator Japanese - Arabic: عليك إيدي عدم
• Translator Japanese - Russian: Вы будете Эди недоступность
• Translator Japanese - Portuguese: Você vai Edie indisponibilidade
• Translator Japanese - Bengali: আপনি Edie অভাবে হবে
• Translator Japanese - French: Vous aurez Edie indisponibilité
• Translator Japanese - Malay: Anda akan Edie ketiadaan
• Translator Japanese - German: Du wirst Edie Verfügbarkeit
• Japanese: エーディーエー‐けっそんしょう
• Translator Japanese - Korean: 에디에 결손 짊어 입니다
• Translator Japanese - Javanese: Sampeyan bakal Edie unavailability
• Translator Japanese - Vietnamese: Bạn sẽ Edie không có sẵn
• Translator Japanese - Tamil: நீங்கள் எடி கிடைக்கப்பெறாததும் தருகிறேன்
• Translator Japanese - Marathi: आपण Edie माघार कराल
• Translator Japanese - Turkish: Adean Corporation
• Translator Japanese - Italian: Avrete Edie indisponibilità
• Translator Japanese - Polish: Będziesz Edie niedostępność
• Translator Japanese - Ukrainian: Ви будете Еді недоступність
• Translator Japanese - Romanian: Veți Edie indisponibilitate
• Translator Japanese - Greek: Θα Εντι διαθεσιμότητας
• Translator Japanese - Afrikaans: Jy sal Edie onbeskikbaarheid
• Translator Japanese - Swedish: Du kommer Edie otillgänglighet
• Translator Japanese - Norwegian: Du vil Edie utilgjengelighet

JAPANESE BOOKS RELATING TO «エーディーエー‐けっそんしょう»

Discover the use of エーディーエー‐けっそんしょう in the following bibliographical selection. Books relating to エーディーエー‐けっそんしょう and brief extracts from same to provide context of its use in Japanese literature.

ルネサンス画人伝

ダンテ『神曲』に比肩する不朽の古典的名著

ジョルジョヴァザーリ, 2009