与 «HYPOMORPH»相关的英语书籍
在以下的参考文献中发现
hypomorph的用法。与
hypomorph相关的书籍以及同一来源的简短摘要提供其在 英语文献中的使用情境。
1
Textbook of Pulmonary Vascular Disease
An alternative BMPR2 knock-in mouse, the hypomorph, has a deletion of exon 2,
causing loss of half of the extracellular binding domain but an otherwise normal
protein. When homozygous, these mice survive gastrulation, but die later in ...
Jason X. -J. Yuan, Joe G.N. Garcia, Charles A. Hales, 2011
2
Behavioral Genetics of the Fly (Drosophila Melanogaster)
... Knocking-down ofendogenous fmr1: UAS-fmrRNAi(1–7), UAS-fmrRNAi(1–10),
UAS-fmrRNAi(2–1), Overexpression of Drosophila fmr1: UAS-fmr1, Hypomorph
mutants: mnb1, mnb2, mnb3, mnb4 Hypomorph mutants: nla1, nla2;Transposon-
...
3
Combinatorics, Geometry and Probability: A Tribute to Paul Erdös
The decision problem (NIH) whether a connected bipartite graph has a non-
isomorphic hypomorph is NP-complete. For the proof, we need some
preparations. Suppose F is an n x m matrix. We call F indecomposable if there is
no partition ...
Paul Erdős, B La Bollob?'s, Andrew Thomason, 1997
4
Genes, Development and Cancer: The Life and Work of Edward ...
If addition of wild-type copies of a gene return the phenotype of a mutant towards
wild type, then the mutant must reduce the normal function of the gene (e.g.,
antimorph, hypomorph, amorph). The last three can be distinguished further by ...
Edward B. Lewis, Howard D. Lipshitz, 2007
5
Identification and Characterization of the E(var)3-5 Gene in ...
The lethality in the hemizygous embryos would be due to one mutant copy of E(
var)3-5 (hypomorph/deficiency) compared to lethality of homozygous embryos
where the lethality would be due to two mutants copies of E(var)3-5 ...
Pranoti Sahasrabhojane, 2008
6
Osteoporosis in Older Persons: Pathophysiology and ...
... ex vivo cell culture Ataxia telangiectasia BubR1 spindle assembly hypomorph
Normal (kyphosis) DXA checkpoint DNA-PKcs DNA repair KO osteopenia X-ray
analysis klotho hormone/growth factor hypomorph osteopenia SXA, microCT, ...
Gustavo Duque, Douglas P. Kiel, 2009
7
Kallmann Syndrome and Hypogonadotropic Hypogonadism
Fgf8 hypomorph Global reduction of functional FGF8 protein due to a splicing
defect caused by neo-cassette insertion. Study effects of global reduction of FGF8
on GnRH system development and postnatal function. Not tissue specific, but ...
8
Behavioral Neurogenetics
Sex Model description/ background/ Basal PPI Effects of drugs or manipulations
Effects of (presumed) antipsychotics/other rationale typically used to induce PPI-
treatments deficits B. GL U TAMA TE NR1 Duncan et al. (2010) NR1 hypomorph
...
John F. Cryan, Andreas Reif, 2012
9
Handbook of the Biology of Aging
... Overexpression Overexpression Overexpression Homozygote Hypomorph*
Overexpression Male Female** Male/ Female Transheterozygote Hypomorph
Homozygote Knockout Heterozygote Hypomorph Dominant Negative
Overexpression ...
Edward J. Masoro, Steven N. Austad, 2011
10
Investigations Into the Role of Dopamine in the Central ...
13 incomplete extreme hypomorph or null 19.56 45/106=42 37/129=29 complete
hypomorph 23.50 27 /87 = 31 6/ 29 =.21 complete hypomorph 29.60 0 / 7=0 9 /
61 =.15 complete extreme hypomorph or null 48.54 18 / 62 =.29 19/66 =.29 ...
Margaret Mary Meller, 1998
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Deletion of Rapgef6, a candidate schizophrenia susceptibility gene …
A Rapgef1 hypomorph mouse (due to early embryonic deletion lethality) had reduced neurons because Rapgef1 mediates neural precursor ... «Nature.com, 六月 15»
TP53: an oncogene in disguise
He proposed the terms 'amorph, 'hypomorph', 'hypermorph', 'neomorph' or 'antimorph'. The significance of these terms was subsequently ... «Nature.com, 五月 15»
Puberty Hormone Tied to Premature Ovarian Failure
Kiss1r hypomorph mice displayed a premature decline in ovulation, followed by progressive loss of antral follicles, oocyte loss, and a reduction ... «MedPage Today, 六月 14»