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frameshift

Meaning of "frameshift" in the English dictionary

DICTIONARY

PRONUNCIATION OF FRAMESHIFT

ˈfreɪmˌʃɪft


GRAMMATICAL CATEGORY OF FRAMESHIFT

noun
adjective
verb
adverb
pronoun
preposition
conjunction
determiner
exclamation
Frameshift is a noun.
A noun is a type of word the meaning of which determines reality. Nouns provide the names for all things: people, objects, sensations, feelings, etc.

WHAT DOES FRAMESHIFT MEAN IN ENGLISH?

Translational frameshift

Translational frameshifting or ribosomal frameshifting refers to an alternate process of protein translation. A protein is translated from one end of the mRNA to the other, from the 5' to the 3' end. Normally a protein is translated from a template mRNA with consecutive blocks of 3 nucleotides being read as single amino acids. However, certain organisms may exhibit a change or shift in the ribosomes frame by one or two nucleotides when translating the genetic code. This is deemed translational or ribosomal frameshifting. The process can be programmed by the nucleotide sequence of the mRNA and is sometimes affected by the secondary or tertiary mRNA structure. It has been described mainly in viruses, retrotransposons and bacterial insertion elements, and also in some cellular genes.

Definition of frameshift in the English dictionary

The definition of frameshift in the dictionary is a frameshift mutation is a genetic mutation in which a number of nucleotides not divisible by three are either inserted into or deleted from a nucleic acid sequence.

WORDS THAT RHYME WITH FRAMESHIFT

blueshift · downshift · gearshift · kerchiefed · loanshift · makeshift · manshift · rankshift · redshift · shift · unshift · upshift

WORDS THAT BEGIN LIKE FRAMESHIFT

framboesia · framboise · frame · frame aerial · frame house · frame line · frame of mind · frame of reference · frame saw · frame tent · frame-up · frameable · frameless · framer · frames · framework · framework agreement · framing · frampler · frampold

WORDS THAT END LIKE FRAMESHIFT

back shift · consonant shift · day shift · Doppler shift · Einstein shift · function shift · graveyard shift · Great Vowel Shift · Lamb shift · night shift · paradigm shift · scene shift · sound shift · split shift · stick shift · swing shift · vowel shift · whift

Synonyms and antonyms of frameshift in the English dictionary of synonyms

SYNONYMS

Translation of «frameshift» into 25 languages

TRANSLATOR

TRANSLATION OF FRAMESHIFT

Find out the translation of frameshift to 25 languages with our English multilingual translator.

The translations of frameshift from English to other languages presented in this section have been obtained through automatic statistical translation; where the essential translation unit is the word «frameshift» in English.
zh

Translator English - Chinese

1,325 millions of speakers
es

Translator English - Spanish

desplazamiento del marco
570 millions of speakers
en

English

frameshift
510 millions of speakers
hi

Translator English - Hindi

frameshift
380 millions of speakers
ar

Translator English - Arabic

انزياح الإطار
280 millions of speakers
ru

Translator English - Russian

рамки считывания
278 millions of speakers
pt

Translator English - Portuguese

frameshift
270 millions of speakers
bn

Translator English - Bengali

frameshift
260 millions of speakers
fr

Translator English - French

déphasage
220 millions of speakers
ms

Translator English - Malay

Frameshift
190 millions of speakers
de

Translator English - German

Frameshift
180 millions of speakers
ja

Translator English - Japanese

フレームシフト
130 millions of speakers
ko

Translator English - Korean

틀 이동
85 millions of speakers
jv

Translator English - Javanese

Frameshift
85 millions of speakers
vi

Translator English - Vietnamese

khung đọc
80 millions of speakers
ta

Translator English - Tamil

ஃப்ரேம்ஷிப்ட்
75 millions of speakers
mr

Translator English - Marathi

फ्रेम्सविफ्ट
75 millions of speakers
tr

Translator English - Turkish

çerçeve kayması
70 millions of speakers
it

Translator English - Italian

frameshift
65 millions of speakers
pl

Translator English - Polish

przesunięcia ramki
50 millions of speakers
uk

Translator English - Ukrainian

рамки зчитування
40 millions of speakers
ro

Translator English - Romanian

frameshift
30 millions of speakers
el

Translator English - Greek

πλαισιοτροποποιητικές
15 millions of speakers
af

Translator English - Afrikaans

raam
14 millions of speakers
sv

Translator English - Swedish

ramskifte
10 millions of speakers
no

Translator English - Norwegian

rammeskift
5 millions of speakers

Trends of use of frameshift

TRENDS

TENDENCIES OF USE OF THE TERM «FRAMESHIFT»

Principal search tendencies and common uses of frameshift
List of principal searches undertaken by users to access our English online dictionary and most widely used expressions with the word «frameshift».

Examples of use in the English literature, quotes and news about frameshift

EXAMPLES

10 ENGLISH BOOKS RELATING TO «FRAMESHIFT»

Discover the use of frameshift in the following bibliographical selection. Books relating to frameshift and brief extracts from same to provide context of its use in English literature.
1
Frameshift
In a near-future thriller, a scientist's complex battle against deadly diseases is challenged when he and his wife are targeted by an ex-Nazi war criminal and a corrupt insurance company's plot to render them guinea pigs in a bizarre ...
Robert J. Sawyer, 2005
2
Computational Intelligence and Bioinformatics: International ...
However, finding ribosomal frameshift sites by a computational method is difficult because frameshift signals are diverse and dependent on the organisms and environments. There are few computer programs available for public use to identify ...
De-Shuang Huang, Kang Li, George William Irwin, 2006
3
PNH and the GPI-Linked Proteins
... Frameshift Frameshift Missense Frameshift Frameshift Missense Missense Frameshift Frameshift Frameshift Nonsense Frameshift Frameshift Frameshift Frameshift Missense Frameshift Frameshift Frameshift Missense/ frameshift Frameshift ...
Neal S. Young, Joel Moss, 2000
4
Inborn Errors of Development: The Molecular Basis of ...
... Hamlington et al., 2001 187insT I Frameshift, PTC Clough et al., 1999 187de146 D Frameshift, PTC Clough et al., 1999 C63R M Disrupt Zn finger Clough et al., 1999 Q64X N PTC Clough et al., 1999 199insTC I Frameshift, PTC Clough et al., ...
Charles J. Epstein, Robert P. Erickson, Anthony Joseph Wynshaw-Boris, 2004
5
Recoding: Expansion of Decoding Rules Enriches Gene ...
The effect of silencing eRF1 could be indirect, reducing the number of ribosomes that initiate translation and, therefore, increasing the probability that these ribosomes encounter a folded frameshift stimulatory signal. It is likely that other cellular ...
John F. Atkins, Raymond F. Gesteland, 2010
6
Plant Virology
Frame0 Frame–1 V G GGGGGGUUU UUUAA U STOP F L E FIGURE 6.24 Translational frameshift. The ribosome bypasses the stop codon in Frame 0 by switching back one nucleotide to Frame –1 at a UUUAG sequence before continuing to ...
Roger Hull, 2013
7
New Messenger RNA Research Communications
A. Note. on. the. Interpretation. of. in. Vitro. Ribosomal. Frameshift. Efficiencies. Maarten H. de Smir8, Maarten Laurs, Cornells W. A. Pleij and Rene C. L. Olsthoorn Section Genexpress, Leiden Institute of Chemistry, Leiden University, ...
Lee B. Kwang, 2007
8
Location of Frameshift Errors Via Comparison with Closely ...
Frameshift errors represent a significant problem in sequenced genomes.
Stephen Snow, 2009
9
Cytochrome
Result ( 1 ) may be produced by only one allele without the frameshift mutation (if the other allele is a D6-D allele known to have a deletion or the entire CYP2D6 gene) or by two alleles without the frameshift mutation. Therefore, the result is ...
Michael R. Waterman, Eric F. Johnson, 1991
10
Computational Science -- ICCS 2005: 5th International ...
Prediction. of. Ribosomal. Frameshift. Signals. of. User-Defined. Models. Yanga Byun, Sanghoon Moon, and Kyungsook Han* School of Computer Science and Engineering, Inha University, Inchon 402-751, Korea {quaah, j iap72 } ...
V.S. Sunderam, G. Dick van Albada, Peter M.A. Sloot, 2005

10 NEWS ITEMS WHICH INCLUDE THE TERM «FRAMESHIFT»

Find out what the national and international press are talking about and how the term frameshift is used in the context of the following news items.
1
Loss-of-function variants in HIVEP2 are a cause of intellectual …
In these three patients, WES revealed two nonsense variants (Patients 1 and 2) and one frameshift variant (Patient 3) in HIVEP2 (NM_006734.3 ... «Nature.com, Jul 15»
2
Homozygosity mapping and whole-genome sequencing reveals a …
Article | PubMed | CAS |; Pras E, Abu A, Rotenstreich Y et al: Cone-rod dystrophy and a frameshift mutation in the PROM1 gene. Mol Vis 2009 ... «Nature.com, Jul 15»
3
Identification of the first large deletion in the CLDN16 gene in a …
... the mutation types in this cohort of patients were more severe in the CLDN19 group, including a large deletion and frameshift mutations [12]. «BMC Blogs Network, Jul 15»
4
Novel mutations in PAX6, OTX2 and NDP in anophthalmia …
Among these variants, 2 were frameshift and 66 were missense. Functional significance analysis of missense variants identified 4 variants ... «Nature.com, Jul 15»
5
Mucolipidosis types II and III and non-syndromic stuttering are …
... II alpha/beta and ML III alpha/beta/gamma, including the c.1399delG and c.3503_3504del frameshift mutations and the c.3335+6 T>C splice ... «Nature.com, Jul 15»
6
Exome Sequencing Uncovers New Monogenic Form of Obesity
The search ultimately led to a truncating frameshift mutation in the first exon of the CPE gene. With the help of Sanger sequencing, the team ... «GenomeWeb, Jun 15»
7
When Home Becomes Your Parents' House
Home continues to frameshift in your mind, with the novelties and excitement of home beginning to take up residence alongside the fading ... «Huffington Post, Jun 15»
8
Bloom Energy Quietly Revises Emissions Estimates
This article is part of FrameShift, NBC Bay Area's Investigative Blog. FrameShift writes on investigative reporting in California and expands the ... «NBC Bay Area, Jun 15»
9
Researchers Link TCF12 Mutations to Aggressive Form of …
The various mutations the researchers uncovered in TCF12 — like the frameshift mutations M260fs*5 and E548fs*13, the missense R602M ... «GenomeWeb, Jun 15»
10
Molecular Characterization of NF1 and Neurofibromatosis Type 1 …
In total, 89 out of the 100 indexed families harbored pathogenic mutations, consisting of 21 nonsense mutations, 26 frameshift mutations, ... «Nature.com, Jun 15»
REFERENCE
« EDUCALINGO. Frameshift [online]. Available <https://educalingo.com/en/dic-en/frameshift>. May 2024 ».
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