10 ENGLISH BOOKS RELATING TO «GENE AMPLIFICATION»
Discover the use of
gene amplification in the following bibliographical selection. Books relating to
gene amplification and brief extracts from same to provide context of its use in English literature.
1
Gene Amplification in Mammalian Cells: A Comprehensive Guide
The book covers the mechanism of gene amplification, organization and structure of amplified genes.
2
Ecdysone Receptor (EcR) Regulates Cell Migration and Chorion ...
Many of the proteins required for DNA replication - including but not limited to
ORC2, Mcm2-7, Cdtl, and CyclinE-CDK - are required for chorion gene
amplification (Calvi et al., 1998; Landis et al., 1997; Schwed et al., 2002; Thomer
et al, 2004).
Jennifer Faye Hackney, 2008
It has been recognized that gene amplification is associated with resistance to a
variety of cancer therapies. Gene amplification can be manifested as multiple
extra copies of a subchromosomal region of an amplicon, termed
extrachromosomal ...
4
Cell Commitment and Differentiation
3.22 A note on gene amplification In our earlier discussion of gene activity and
regulation and the different categories of nuclear genes, no mention was made of
a remarkable cellular phenomenon. This phenomenon is highly specialized and
...
Norman Maclean, Brian Keith Hall, 1987
5
Human Molecular Biology: An Introduction to the Molecular ...
Such acquisition of increased gene copy number is termed gene amplification.
Figure 2.18 Microevolution of gene amplification in response to selective
pressure. Gene copy number increases in proportion to the lethality of the
selection ...
6
Gene Transfer and Expression in Mammalian Cells
The diagram in Fig. 2 does not distinguish between gene amplification in pools of
cells or gene amplification in individually isolated clonal cell lines. We favor
single-clone gene amplifications, although this may not necessarily be the
preferred ...
Gene Amplification and Chromosome Abnormalities Gene amplification was first
characterized as a common mechanism by which mammalian cells acquire
resistance to metabolic inhibitors and is often seen in tumor cells that have
become ...
High clone to clone variations as well as instability in expression levels after
amplification have been shown to be due to severe genetic rearrangements
during gene amplification as well as to the emergence of drug-resistance. Hence,
the ...
9
Rubin's Pathology: Clinicopathologic Foundations of Medicine
Activation by Gene Amplification Chromosomal alterations that result in an
increased number of gene copies (i.e., gene amplification) have been found
primarily in human solid tumors. Such aberrations are recognized as (1)
homogeneous ...
Raphael Rubin, David S. Strayer, Emanuel Rubin, 2008
As gene amplification is often initially unstable and becomes stable only when
cells are maintained under selective conditions for a long time, prolonged
exposure to a single treatment regimen should perhaps be avoided. It seems
quite clear ...
10 NEWS ITEMS WHICH INCLUDE THE TERM «GENE AMPLIFICATION»
Find out what the national and international press are talking about and how the term
gene amplification is used in the context of the following news items.
Fecal microbiota transplantation restores dysbiosis in patients with …
The genotypes of SCCmec were determined by multiplex PCR. According to the results of STR parting, the length of SCCmec gene amplification in the sample is ... «BMC Blogs Network, Jul 15»
Genetic screening reveals a link between Wnt signaling and …
Consistent with the lack of evidence for DHFR gene amplification, there was no significant difference in the expression of the gene between ... «Nature.com, Jul 15»
New Agents Aimed at Unique Targets Show Promise in Gastric Cancer
... with advanced gastric cancer (AGC) with Fibroblast Growth Factor Receptor 2 (FGFR2) polysomy or gene amplification (amp): SHINE study. «OncLive, Jul 15»
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Estrogen receptor alpha (ESR1) gene amplification is frequent in breast cancer. Nat Genet 2007, 39(5):655-660. PubMed Abstract | Publisher ... «BMC Blogs Network, Jul 15»
Glioma invasion mediated by the p75 neurotrophin receptor (p75 …
Expression and gene amplification of actinin-4 in invasive ductal carcinoma of the pancreas. Clin Cancer Res 2008; 14: 5348–5356. «Nature.com, Jun 15»
MYC in pancreatic cancer: novel mechanistic insights and their …
In addition to gene amplification and promoter transactivation, regulation of post-transcriptional processes constitutes another layer in ... «Nature.com, Jun 15»
Comprehensive translational control of tyrosine kinase expression …
Although overexpression or constitutive activation of tyrosine kinases (TKs) through gene amplification, translocation or mutation are ... «Nature.com, Jun 15»
Brome develops unique resistance
In gene amplification, the resistant plant produces numbers of copies of the gene responsible for the enzyme EPSPS which is targeted by ... «Farm Weekly, Jun 15»
Scientists unlock resistance secret
In gene amplification, the resistant plant produces many copies of the gene responsible for the enzyme EPSPS that is targeted by glyphosate. «Stock Journal, Jun 15»
Forks Colliding: How DNA Breaks During Re-Replication
Moreover, because errors arising during DNA replication and gene amplification result in chromosomal abnormalities often found in malignant ... «Newswise, Jun 15»
