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Meaning of "heavy chain" in the English dictionary

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DICTIONARY
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PRONUNCIATION OF HEAVY CHAIN

heavy chain play
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GRAMMATICAL CATEGORY OF HEAVY CHAIN

noun
adjective
verb
adverb
pronoun
preposition
conjunction
determiner
exclamation
Heavy chain is a noun.
A noun is a type of word the meaning of which determines reality. Nouns provide the names for all things: people, objects, sensations, feelings, etc.

WHAT DOES HEAVY CHAIN MEAN IN ENGLISH?

heavy chain

Heavy chain

A heavy chain is the large polypeptide subunit of a protein complex, such as a motor protein or antibody. It commonly refers to the immunoglobulin heavy chain. The heavy chain is the larger of the two types of chains that comprise a normal immunoglobulin or antibody molecule. The heavy chain portion of an antibody contains 2 regions; the Fab and Fc. Amino acid sequence determines the type of heavy chains, and heavy chains define the isotype of Ig. Immunoglobulin G has γ gamma heavy chains, IgA has α alpha heavy chains, IgM has μ mu heavy chains, IgD has δ delta heavy chains, and IgE has ε epsilon heavy chains. In contrast, all light chains are either κ kappa or λ lambda light chains, either of which may be found on any Ig molecule, regardless of isotype. Each Ig unit is made up of 2 heavy chains, 2 light chains, and has 2 antigen-binding sites. Heavy chain is joined with the light chain with the help of disulphide bond.

Definition of heavy chain in the English dictionary

The definition of heavy chain in the dictionary is a type of polypeptide chain present in an immunoglobulin molecule.

WORDS THAT BEGIN LIKE HEAVY CHAIN

heavy breather
heavy breathing
heavy cream
heavy crude
heavy crude oil
heavy cruiser
heavy earth
heavy element
heavy going
heavy goods vehicle
heavy hitter
heavy hydrogen
heavy industry
heavy metal
heavy middleweight
heavy mob
heavy mud
heavy oil
heavy on
heavy spar

WORDS THAT END LIKE HEAVY CHAIN

ball and chain
branched chain
chain
curb chain
daisy chain
door chain
drive chain
fast-food chain
food chain
grand chain
hain
hotel chain
long-chain
Markov chain
mountain chain
open chain
paper chain
side chain
straight chain
supply chain
unchain

Synonyms and antonyms of heavy chain in the English dictionary of synonyms

SYNONYMS

Translation of «heavy chain» into 25 languages

TRANSLATOR
online translator

TRANSLATION OF HEAVY CHAIN

Find out the translation of heavy chain to 25 languages with our English multilingual translator.
The translations of heavy chain from English to other languages presented in this section have been obtained through automatic statistical translation; where the essential translation unit is the word «heavy chain» in English.

Translator English - Chinese

重链
1,325 millions of speakers

Translator English - Spanish

cadena pesada
570 millions of speakers

English

heavy chain
510 millions of speakers

Translator English - Hindi

भारी श्रृंखला
380 millions of speakers
ar

Translator English - Arabic

السلسلة الثقيلة
280 millions of speakers

Translator English - Russian

тяжелой цепи
278 millions of speakers

Translator English - Portuguese

cadeia pesada
270 millions of speakers

Translator English - Bengali

ভারী শ্বাস
260 millions of speakers

Translator English - French

chaîne lourde
220 millions of speakers

Translator English - Malay

sesak nafas
190 millions of speakers

Translator English - German

schwere Kette
180 millions of speakers

Translator English - Japanese

重鎖
130 millions of speakers

Translator English - Korean

중쇄
85 millions of speakers

Translator English - Javanese

Napas abot
85 millions of speakers
vi

Translator English - Vietnamese

chuỗi nặng
80 millions of speakers

Translator English - Tamil

அதிக சுவாசம்
75 millions of speakers

Translator English - Marathi

जड श्वास
75 millions of speakers

Translator English - Turkish

Ağır solunum
70 millions of speakers

Translator English - Italian

catena pesante
65 millions of speakers

Translator English - Polish

łańcuch ciężki
50 millions of speakers

Translator English - Ukrainian

важкого ланцюга
40 millions of speakers

Translator English - Romanian

lanț greu
30 millions of speakers
el

Translator English - Greek

βαριάς αλυσίδας
15 millions of speakers
af

Translator English - Afrikaans

swaar ketting
14 millions of speakers
sv

Translator English - Swedish

tung kedja
10 millions of speakers
no

Translator English - Norwegian

tung kjede
5 millions of speakers

Trends of use of heavy chain

TRENDS

TENDENCIES OF USE OF THE TERM «HEAVY CHAIN»

The term «heavy chain» is regularly used and occupies the 74.140 position in our list of most widely used terms in the English dictionary.
0
100%
FREQUENCY
Regularly used
66
/100
The map shown above gives the frequency of use of the term «heavy chain» in the different countries.
Principal search tendencies and common uses of heavy chain
List of principal searches undertaken by users to access our English online dictionary and most widely used expressions with the word «heavy chain».

FREQUENCY OF USE OF THE TERM «HEAVY CHAIN» OVER TIME

The graph expresses the annual evolution of the frequency of use of the word «heavy chain» during the past 500 years. Its implementation is based on analysing how often the term «heavy chain» appears in digitalised printed sources in English between the year 1500 and the present day.

Examples of use in the English literature, quotes and news about heavy chain

EXAMPLES

10 ENGLISH BOOKS RELATING TO «HEAVY CHAIN»

Discover the use of heavy chain in the following bibliographical selection. Books relating to heavy chain and brief extracts from same to provide context of its use in English literature.
1
Mechanistic and Genetic Biases in Human Immunoglobulin Heavy ...
Together, these analyses provide new insights into the genetic and mechanistic biases shaping the human Ig repertoire.
Joseph M. Volpe, 2008
2
Clinical Laboratory Medicine
The immunoglobulin heavy chain gene is located on chromosome I4q32, the kappa light chain gene on chromosome 2pl2, and the lambda light chain gene on chromosome 22ql 1 . The first rearrangement step in the early B-precursor cell ...
Kenneth D. McClatchey, 2002
3
Skeletal Muscle: Form and Function
It is now established that there are at least four major heavy chain isoforms and eight light chain isoforms in adult mammalian muscle (Staron & Pette. 1990). The four myosin heavy chain isoforms of importance in limb muscles are I, Ila, IIx, and  ...
Brian R. MacIntosh, Phillip F. Gardiner, Alan J. McComas, 2006
4
Sequences of Proteins of Immunological Interest
PRECURSOR OF: 1) YTH 34.5BL'CL: RAT HEAVY CHAIN 2) VHl-a2'CL: RABBIT HEAVY CHAIN 3) РМСЗ'СХ: RABBIT HEAVY CHAIN 4) VH4-a2'CL: RABBIT HEAVY CHAIN 5) p26.9a3'CL: RABBIT HEAVY CHAIN 6) RVH608'CL: RABBIT ...
Elvin A. Kabat, Tai Te Wu, Harold M. Perry, 1992
5
Illustrated Dictionary of Immunology, Third Edition
IgG, and IgG4 have two inter-heavy chain disulfide bonds, IgG2 has four, and IgG3 has 11. Proteolytic enzymes such as papain and pepsin cleave an IgG molecule in the hinge region to produce Fab and F(ab')2 and Fc fragments. Four murine ...
Julius M. Cruse, Robert E. Lewis, 2009
6
Pathology and Genetics of Tumours of Haematopoietic and ...
The pathological monoclonal immunoglobulin component is composed of either IgG (Gamma heavy chain disease), IgA (Alpha heavy chain disease) or IgM (Mu heavy chain disease). The heavy chain immunoglobulin is usually an incomplete  ...
Elaine Sarkin Jaffe, 2001
7
Neoplastic Diseases of the Blood
The histopathology of gamma heavy-chain disease. Am J Clin Pathol. 1982;78: 427–36. Bloch KJ, Lee L, Mills JA, Haber E. Gamma heavy chain disease: an expanding clinical and laboratory spectrum. Am J Med. 1973;55:61–70. Gallart MT ...
Peter H. Wiernik, John M. Goldman, Janice Dutcher, 2012
8
Essentials of Immunology and Serology
Each light chain is covalently bound to a heavy chain. The two heavy chains are covalently bound. bound to a heavy chain and the heavy chains are, in turn, covalently bound to each other, as described in Figure 3-2. The light and heavy ...
Jacqueline Stanley, 2002
9
Functional Study of the 3' Regulatory Region of the ...
... form a complete variable region transcriptional unit at the large pre-B cell stage . At this point, the B cells are able to express the pre-B cell receptor on their surface, which is composed of the Igμ heavy chain together with surrogate light chain ...
Yi Yan, 2007
10
Molecular Biology and Biotechnology: A Comprehensive Desk ...
Myosin II is comprised of two heavy chain polypeplides each with a globular head and a rod region, which interacts with a second heavy chain to form an a- helical coiled-coil shaft. Each myosin heavy chain has a pair of light chains I regulatory ...
Robert A. Meyers, 1995

10 NEWS ITEMS WHICH INCLUDE THE TERM «HEAVY CHAIN»

Find out what the national and international press are talking about and how the term heavy chain is used in the context of the following news items.
1
Montgomery man arrested after dog found with heavy chain
A Montgomery man was arrested after an Akita dog was found with a heavy chain embedded in its neck at his residence in early May. «AL.com, Jul 15»
2
Supplementary information - Nature
... troponin T (cTnT), sarcomeric α-actinin and myosin heavy chain, whereas cells on the perimeter expressed the myofibroblast markers SM22, ... «Nature.com, Jul 15»
3
Pit Bulls Locked In Sweltering Wooden Box Get No Help From Police
In the same backyard is another dog on a heavy chain with no food or water." Facebook/Roxanne Weeks. Officers were reportedly dispatched ... «The Dodo, Jul 15»
4
FSU RB Dalvin Cook cited in 2014 for chaining 3 pit bull puppies …
“The dogs were tethered directly around the neck by a heavy chain,” animal control officer Sheree Mifflin wrote in the official report (which you ... «CBS sports.com, Jul 15»
5
FSU cracking down after 2 football players arrested | News - Home
A new report released by Tallahassee Animal Services shows that Cook was issued a citation for chaining up three puppies with a heavy chain ... «WJXT Jacksonville, Jul 15»
6
Florida State president warns football team about misconduct
... three puppies (one aged eight months and two that were just two months old) … tethered directly around the neck by a heavy chain”. The dog ... «Ledger Gazette, Jul 15»
7
Bar Zing!s - Tallahassee Democrat
"The larger puppies were unable to move and the smaller puppies were choking" from a heavy chain that had been tied around their necks. «Tallahassee.com, Jul 15»
8
Florida State Dalvin Cook was cited for chaining puppies together
“The dogs were tethered directly around the neck by a heavy chain,” animal control officer Sheree Mifflin wrote. “The dogs were unable to move ... «Boston Sun Times, Jul 15»
9
Florida State president John Thrasher warns Seminoles about …
“The dogs were tethered directly around the neck by a heavy chain”, animal control officer Sheree Mifflin wrote in the official report (which you ... «iFreePress.com, Jul 15»
10
“Get him off me — he's killing me!” Dog cleared in sudden death
... see the man's companion standing frozen on the sidewalk holding the dog's leather collar and the length of heavy chain that was his leash. «Hamilton Spectator, Jul 15»

REFERENCE
« EDUCALINGO. Heavy chain [online]. Available <https://educalingo.com/en/dic-en/heavy-chain>. May 2024 ».
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