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WHAT DOES IMMUNE COMPLEX MEAN IN ENGLISH?
An immune complex is formed from the integral binding of an antibody to a soluble antigen. The bound antigen and antibody act as a specific epitope, and is referred to as a singular immune complex. After an antigen-antibody reaction, the immune complexes can be subject to any of a number of responses, including complement deposition, opsonization, phagocytosis, or processing by proteases. Red blood cells carrying CR1-receptors on their surface may bind C3b-decorated immune complexes and transport them to phagocytes, mostly in liver and spleen, and return to the general circulation. Immune complexes may themselves cause disease when they are deposited in organs, e.g. in certain forms of vasculitis. This is the third form of hypersensitivity in the Gell-Coombs classification, called Type III hypersensitivity. Immune complex deposition is a prominent feature of several autoimmune diseases, including systemic lupus erythematosus, cryoglobulinemia, rheumatoid arthritis, scleroderma and Sjögren's syndrome.
The translations of immune complex from English to other languages presented in this section have been obtained through automatic statistical translation; where the essential translation unit is the word «immune complex» in English.
List of principal searches undertaken by users to access our English online dictionary and most widely used expressions with the word «immune complex».
FREQUENCY OF USE OF THE TERM «IMMUNE COMPLEX» OVER TIME
The graph expresses the annual evolution of the frequency of use of the word «immune complex» during the past 500 years. Its implementation is based on analysing how often the term «immune complex» appears in digitalised printed sources in English between the year 1500 and the present day.
Examples of use in the English literature, quotes and news about immune complex
10 ENGLISH BOOKS RELATING TO «IMMUNE COMPLEX»
Discover the use of immune complex in the following bibliographical selection. Books relating to immune complex and brief extracts from same to provide context of its use in English literature.
Primer on the Rheumatic Diseases
In immune complex vasculitis, immune complexes deposit in the vascular
endothelium or in capillary beds, such as those found in the skin, kidneys, or
lungs. The most common skin manifestation of small vessel vasculitis is palpable
John H. Klippel, John H. Stone, L eslie J. Crofford, 2008
Dubois' Lupus Erythematosus
The efficiency of mononuclear phagocyte system immune complex clearance
depends on the function of Fey receptors, receptors recognizing the Fc region of
immunoglobulin, and the complement receptors. In SLE, inadequate clearance ...
Daniel Jeffrey Wallace, Bevra Hahn, 2007
I Since the recognition of the in situ mechanism of glomerular immune complex
formation, the concept of the entrapment of immune complexes preformed in the
circulation has been increasingly challenged. It is now believed that most
Ellis D. Avner, William Harmon, Patrick Niaudet, 2004
Heptinstall's Pathology of the Kidney
Immune complex vasculitis most often affects venules, especially dermal venules,
and capillaries, especially glomerular capillaries. Therefore, purpura and
nephritis are frequent clinical manifestations of immune complex vasculitis, along
J. Charles Jennette, 2007
Immunology: A Short Course
Systemic Lupus Erythematosus Patients with SLE often have both systemic (
multiorgan) and localized manifestations of immune complex disease. Localized
tissue injury occurs as a result of the formation of antigen–antibody complexes (in
Richard Coico, Geoffrey Sunshine, 2009
Systemic Lupus Erythematosus: A Companion to Rheumatology
The later phase of immune complex clearance was exponential over the 60
minutes of measurement, with between 9.9 and 18.7% removed per minute in
normals and 8.6 to 32.2% per minute removed in patients. When opsonized
George C. Tsokos, Caroline Gordon, Josef S. Smolen, 2007
Color Atlas of Pathology: Pathologic Principles, Associated ...
tm Serum Disease Synonym: systemic immune complex disease. Definition:
Immune reaction due to incompatibility of foreign serum. Etiologic factors include:
— Foreign serum; — Foreign globulins and other foreign proteins; — Haptens
Ursus-Nikolaus Riede, Martin Werner, 2011
Differences between the various immune-complex models reside mainly in the
subclasses of antibodies (Table 22.3) and related complement-binding activity or
Fey receptor-mediated activation of granulocytes, macrophages, and mast cells.
E. William St. Clair, David S. Pisetsky, Barton F. Haynes, 2004
Clinical Environmental Health and Toxic Exposures
The syndrome consists of pulmonary hemorrhage and nephritis with immunecomplex deposition. TYPE III HYPERSENSITIVITY REACTION (IMMUNECOMPLEX DISEASE) Immune complexes occur when antibody contacts antigen
and the ...
John Burke Sullivan, Gary R. Krieger, 2001
Rheumatology: Diagnosis and Therapeutics
Deposition of immune complexes in specific tissues depends on a number of
factors related to the immune complex itself as well as local factors. For example,
the size of immune complexes is critical. Very small immune complexes (typically
John J. Cush, Arthur Kavanaugh, Charles Michael Stein, 2005
10 NEWS ITEMS WHICH INCLUDE THE TERM «IMMUNE COMPLEX»
Find out what the national and international press are talking about and how the term immune complex is used in the context of the following news items.
Clinical & Translational Immunology - Clinical development …
... be used when the reaction is mediated by an immunologic mechanism, for example, IgE, IgG and immune complex complement related. «Nature.com, Jul 15»
Toward A Universal Flu Vaccine
Antibodies bind to a flu virus protein (grey) with their variable regions (blue) forming an immune complex. The antibodies' Fc region (red) will ... «Science 2.0, Jul 15»
Discovery points to a new path toward a universal flu vaccine
Antibodies bind to a flu virus protein (grey) with their variable regions (blue) forming an immune complex. The antibodies' Fc region (red) will ... «Medical Xpress, Jul 15»
Global Markets for Allergy Diagnostics and Treatments
Information on different types of allergic reactions, including anaphylactoid reactions, cytotoxic and cytolytic reactions, immune complex ... «PR Newswire, Jun 15»
Feed a Concussion: Speedy Nutrient Support Offers the Hope of …
Neurogenic amplification of immune complex inflammation. Science, 1996;273:1722. Davis KA, et al. Complement deficiency and immune complex diseases. «Dynamic Chiropractic, Jun 15»
Industry Trend Analysis - EMA Lupus Guideline Will Encourage New …
... of numerous autoantibodies and immune complex formation causing tissue injury and organ damage are believed to play a central role in the pathogenesis. «Pharmaceuticals & Healthcare Insight, Jun 15»
Clinical Review: Systemic lupus erythematosus
... including polymorphisms involved in antigen presentation, Tand B-cell signalling, immune complex clearance and toll-like receptor pathways ... «GP online, May 15»
Bronchial lesions of mouse model of asthma are preceded by …
We conclude that the asthma like lung lesions induced in these models is preceded by immune complex-mediated eosinophilic vasculitis and ... «Nature.com, May 15»
Celgene's Revlimid Patent Families Do Not Appear To Meet Criteria …
In particular, it appears that thalidomide may alleviate neutrophil-mediated cytoxicity and inflammation in immune complex disease." Sampaio ... «Nasdaq, May 15»
Evotec AG Reports Results of First Quarter 2015
... of protein-arginine deiminases (PADs) enzymes with an important role in the generation of autoantigens, inflammation and immune complex ... «GlobeNewswire, May 15»
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