10 ENGLISH BOOKS RELATING TO «LEUKEMOGENIC»
Discover the use of
leukemogenic in the following bibliographical selection. Books relating to
leukemogenic and brief extracts from same to provide context of its use in English literature.
1
On the
Leukemogenic Mechanisms of Core Binding Factor ...
Core binding factor translocations and inversions are among the most frequently identified mutations in acute myeloid leukemia.
2
Manual of Clinical Oncology
Alkylating agents are the drugs with the most clearly demonstrated leukemogenic
potential. Melphalan and chlorambucil are most often associated with AML in this
class of drugs. b. Other drugs. Epipodophyllotoxins (etoposide, teniposide) ...
Casciato, Mary C. Territo, 2012
3
Regulation of Self-renewal by
Leukemogenic Mutations ...
Acute promyelocytic leukemia (APL) is a subtype of acute myeloid leukemia (AML) that accounts for about 5-10% of cases of AML and is characterized by hyperproliferation of promyelocytic progenitors.
4
The Chemotherapy Source Book
Radiotherapy neither increased the risk of leukemia nor enhanced the
leukemogenic effect of chemotherapy. Again, cumulative dose seems important,
as excess leukemias in the ovarian cancer trials occurred among the women who
received ...
Michael Clinton Perry, 2008
5
ADVANCES IN CANCER RESEARCH
Although such mutant gene loci have been characterized in respect to their
influence on normal hematopoiesis, only a few of these have been tested in
respect to their influence on the action of the acute leukemogenic viruses. Such
an ...
George Klein, Sidney Weinhouse, 1987
6
Regulatory Networks in Stem Cells
The fundamental point is whether the leukemogenic event dictates the cell
phenotype or whether the cell type in which this mutation occurs may influence
the phenotype of the abnormality. One can envisage different situations where
either or ...
Vinagolu K. Rajasekhar, 2009
7
Neoplastic Diseases of the Blood
In accord, an artificial recombinant transgene in which an HDAC, the key effector
of RARa- mediated corepressor activity (see RARa section), tethered to RARa
was not leukemogenic [103]. In meticulous experiments with a variety of naturally
...
Peter H. Wiernik, John M. Goldman, Janice Dutcher, 2012
8
Issues in Hematology: 2011 Edition
HOXA. cluster. genes. A new study, 'Leukemogenic transformation by HOXA
cluster genes,' is now available. “HOX homeobox genes are important regulators
of normal and malignant hematopoiesis. Abdominal-type HOXA genes like
HOXA9 ...
9
Acute Myelogenous Leukemia: Genetics, Biology and Therapy
Leukemogenic. Heterozygous mutations as well as downregulation of PU.1 by
leukemogenic fusion proteins indicate a scenario in which critically lowered
transcription factor activity acts leukemogenic. This is supported by a number of
animal ...
10
Leukemia: New Insights for the Healthcare Professional: 2013 ...
Our news journalists obtained a quote from the research, “Reprogrammed TFs
originate from transcriptional alterations of CpG methylation patterns of mutated
epigenetic genes. They preserve memory information of earlier leukemogenic ...
10 NEWS ITEMS WHICH INCLUDE THE TERM «LEUKEMOGENIC»
Find out what the national and international press are talking about and how the term
leukemogenic is used in the context of the following news items.
Peripheral blood cells from children with RASopathies show …
Leukemogenic Ptpn11 causes fatal myeloproliferative disorder via cell-autonomous effects on multiple stages of hematopoiesis. Blood 2009 ... «Nature.com, Jul 15»
The oncofusion protein FUS–ERG targets key hematopoietic …
Retroviral transduction of TLS-ERG initiates a leukemogenic program in normal human hematopoietic cells. Proc Natl Acad Sci USA 1998; 95: ... «Nature.com, Jul 15»
Cyclacel's Second-Generation CDK2/9 Inhibitor, CYC065 …
... may also inhibit CDK9-dependent oncogenic and leukemogenic pathways, including malignancies driven by certain oncogenes and MLL-r. «MarketWatch, Apr 15»
Acute promyelocytic leukemia: where did we start, where are we …
... therefore, the omission of potentially leukemogenic cytotoxic chemotherapy is an attractive option to attempt to reduce the incidence of this ... «Nature.com, Apr 15»
RUNX1/ETO blocks selectin-mediated adhesion via epigenetic …
... recapitulating a naturally occurring highly leukemogenic splice variant RE9a observed in AML patients. RE harbors the DNA-binding domain ... «Nature.com, Apr 15»
Novel drug inhibits MLL leukemia progression in mice [PreClinical]
MLL translocation leads to production of MLL fusion proteins, which in turn causes the acute leukemia. The leukemogenic activity of these MLL ... «2 Minute Medicine, Apr 15»
Leukemia Cells Transformed Into Non-Cancerous Immune Cells
... remain in a “leukemogenic state.” The authors discovered that B-cell leukemia cells could indeed be reprogrammed to macrophage-like cells ... «Immuno-Oncology News, Mar 15»
Amonafide Regimen Not Superior to Standard Care in Secondary AML
... syndrome was associated with a complete response rate of 40% compared with 50% in patients with prior leukemogenic exposure (P = .04); ... «Cancer Network, Mar 15»
Environmentalists Concerned Merger May Open Door for Uranium …
... several studies suggest the possibility of leukemogenic, genetic, reproductive, and neurological effects from chronic exposure to the element. «Utah Political Capitol, Nov 14»
WHY HAVEN'T STATES KICKED MONSANTO OUT?
... Journal of Hematology & Thromboembolic Diseases reveals the potential "leukemogenic" properties of the Bt toxin biopesticides engineered ... «NewsWithViews.com, Nov 14»
