Download the app
educalingo
Search

Meaning of "ligase" in the English dictionary

Dictionary
DICTIONARY
section

PRONUNCIATION OF LIGASE

ligase  [ˈlaɪˌɡeɪz] play
facebooktwitterpinterestwhatsapp

GRAMMATICAL CATEGORY OF LIGASE

noun
adjective
verb
adverb
pronoun
preposition
conjunction
determiner
exclamation
Ligase is a noun.
A noun is a type of word the meaning of which determines reality. Nouns provide the names for all things: people, objects, sensations, feelings, etc.

WHAT DOES LIGASE MEAN IN ENGLISH?

Ligase

In biochemistry, ligase is an enzyme that can catalyze the joining of two large molecules by forming a new chemical bond, usually with accompanying hydrolysis of a small chemical group dependent to one of the larger molecules or the enzyme catalyzing the linking together of two compounds, e.g., enzymes that catalyze joining of C-O, C-S, C-N, etc. In general, a ligase catalyzes the following reaction: Ab + C → A–C + b or sometimes Ab + cD → A–D + b + c where the lowercase letters signify the small, dependent groups. Ligase can join two complementary fragments of nucleic acid and repair single stranded breaks that arise in double stranded DNA during replication.

Definition of ligase in the English dictionary

The definition of ligase in the dictionary is any of a class of enzymes that catalyse the formation of covalent bonds and are important in the synthesis and repair of biological molecules, such as DNA.

WORDS THAT RHYME WITH LIGASE


agaze
əˈɡeɪz
always
ˈɔːlweɪz
anyways
ˈɛnɪˌweɪz
begaze
bɪˈɡeɪz
bez
beɪz
blaze
bleɪz
days
deɪz
gaze
ɡeɪz
Hayes
heɪz
haze
heɪz
hollandaise
ˌhɒlənˈdeɪz
outgaze
ˌaʊtˈɡeɪz
pes
peɪz
phase
feɪz
phrase
freɪz
praise
preɪz
raise
reɪz
stargaze
ˈstɑːˌɡeɪz
stays
steɪz
upgaze
ʌpˈɡeɪz

WORDS THAT BEGIN LIKE LIGASE

lig
ligament
ligamental
ligamentary
ligamentous
ligan
ligand
ligate
ligation
ligative
ligature
liger
Ligeti
ligged
ligger
ligging
light
light air
light aircraft
light ale

WORDS THAT END LIKE LIGASE

base
case
case-by-case
chase
database
decrease
disease
ease
in any case
in case
in no case
increase
lease
on the increase
please
press release
purchase
release
showcase
worst case

Synonyms and antonyms of ligase in the English dictionary of synonyms

SYNONYMS

Translation of «ligase» into 25 languages

TRANSLATOR
online translator

TRANSLATION OF LIGASE

Find out the translation of ligase to 25 languages with our English multilingual translator.
The translations of ligase from English to other languages presented in this section have been obtained through automatic statistical translation; where the essential translation unit is the word «ligase» in English.

Translator English - Chinese

连接酶
1,325 millions of speakers

Translator English - Spanish

ligasa
570 millions of speakers

English

ligase
510 millions of speakers

Translator English - Hindi

ligase
380 millions of speakers
ar

Translator English - Arabic

يغاز
280 millions of speakers

Translator English - Russian

лигазы
278 millions of speakers

Translator English - Portuguese

ligase
270 millions of speakers

Translator English - Bengali

ligase
260 millions of speakers

Translator English - French

ligase
220 millions of speakers

Translator English - Malay

Ligase
190 millions of speakers

Translator English - German

Ligase
180 millions of speakers

Translator English - Japanese

リガーゼ
130 millions of speakers

Translator English - Korean

리가
85 millions of speakers

Translator English - Javanese

Ligase
85 millions of speakers
vi

Translator English - Vietnamese

ligase
80 millions of speakers

Translator English - Tamil

ligase
75 millions of speakers

Translator English - Marathi

Ligase
75 millions of speakers

Translator English - Turkish

ligaz
70 millions of speakers

Translator English - Italian

ligasi
65 millions of speakers

Translator English - Polish

ligazy
50 millions of speakers

Translator English - Ukrainian

лігази
40 millions of speakers

Translator English - Romanian

ligase
30 millions of speakers
el

Translator English - Greek

λιγάση
15 millions of speakers
af

Translator English - Afrikaans

ligase
14 millions of speakers
sv

Translator English - Swedish

ligas
10 millions of speakers
no

Translator English - Norwegian

ligase
5 millions of speakers

Trends of use of ligase

TRENDS

TENDENCIES OF USE OF THE TERM «LIGASE»

The term «ligase» is regularly used and occupies the 61.425 position in our list of most widely used terms in the English dictionary.
0
100%
FREQUENCY
Regularly used
72
/100
The map shown above gives the frequency of use of the term «ligase» in the different countries.
Principal search tendencies and common uses of ligase
List of principal searches undertaken by users to access our English online dictionary and most widely used expressions with the word «ligase».

FREQUENCY OF USE OF THE TERM «LIGASE» OVER TIME

The graph expresses the annual evolution of the frequency of use of the word «ligase» during the past 500 years. Its implementation is based on analysing how often the term «ligase» appears in digitalised printed sources in English between the year 1500 and the present day.

Examples of use in the English literature, quotes and news about ligase

EXAMPLES

10 ENGLISH BOOKS RELATING TO «LIGASE»

Discover the use of ligase in the following bibliographical selection. Books relating to ligase and brief extracts from same to provide context of its use in English literature.
1
Nucleic Acid Amplification Technologies: Application to ...
This book is designed for all biomedical scientists interested in the application of molecular biology to clinical diagnosis."--BOOK JACKET.Title Summary field provided by Blackwell North America, Inc. All Rights Reserved
Helen H. Lee, Stephen A. Morse, Ørjan Olsvik, 1997
2
Enzymology Primer for Recombinant DNA Technology
RNA LIGASE: T4 RNA LIGASE [Polyribonucleotide synthase (ATP), EC 6.5.1.3] RNA ligases catalyze the 3' — > 5' phosphodiester bond formation of RNA molecules with concomitant hydrolysis of ATP to AMP and PP; . Initially detected as an ...
Hyone-Myong Eun, 1996
3
Base Excision Repair of DNA Damage
replication, at least during early embryogen- esis.46 Studies on DNA replication and DNA repair in cell lines established from these DNA ligase I mutant embryos should prove informative. DNA LIGASE II PHYSICAL AND BIOCHEMICAL ...
Ian D. Hickson, 1997
4
DNA Replication
This was readily demonstrated in the first step, the formation of ligase-adenylate, but was technically difficult to prove in the next two steps, the formation and consumption of DNA-adenylate. An interesting kinetic feature is the activation of E.
Arthur Kornberg, Tania A. Baker, 2005
5
RNA-Protein Interactions : A Practical Approach: A Practical ...
ligase' reflected this ability (29, 30). Like T4 RNA ligase, T4 DNA ligase joins the 3' OH of a 5' acceptor polynucleotide to a 5' terminal monophosphate of a 3' donor polynucleotide in the presence of ATP. However, unlike T4 RNA ligase, ...
Christopher W.J. Smith, 1998
6
A Laboratory Guide to RNA: Isolation, Analysis, and Synthesis
Isolation, Analysis, and Synthesis Paul A. Krieg. merase I, and RNase H, and E. coli DNA ligase. The conditions and enzyme concentrations for second-strand cDNA synthesis have been optimized to produce high yields of double-stranded  ...
Paul A. Krieg, 1996
7
Molecular Biology: A Project Approach
Ligase, an enzyme that uses ATP to form bonds, is used in recombinant DNA cloning to join restriction endonuclease fragments that have annealed. The ligase commonly used is T4 DNA ligase, which was first isolated from E. coJi that were ...
Susan J. Karcher, 1995
8
Recombinant DNA Principles and Methodologies
The ligase has a relatively low turnover number of 25 sealing events per minute per ligase molecule. The polyionic polymer PEG 8000 greatly enhances the rate of phosphodiester bond formation by ligase, presumably by increasing the local ...
James Greene, 1998
9
Proteomics of Spermatogenesis
multi-cellular eukaryotes contain more than one species of DNA ligase. DNA ligase I is required for DNA replication involved in DNA repair. Pol-[5 and DNA ligase-l seem to be components of a multi-protein complex that performs base ...
G. S. Gupta, 2006
10
Experimental Techniques in Bacterial Genetics
co/i and S. typhimurium have an NAD dependent DNA ligase that is essential for repairing nicks generated during DNA replication and recombination in vivo . The DNA ligase commonly u sed for DNA cloning is made by phage T4. In contrast ...
Stanley R. Maloy, 1990

10 NEWS ITEMS WHICH INCLUDE THE TERM «LIGASE»

Find out what the national and international press are talking about and how the term ligase is used in the context of the following news items.
1
Spectrum and frequencies of BRCA1/2 mutations in Bulgarian high …
... in the RING domain and abolished the ubiquitin ligase activity of BRCA1 protein as well as its participation in the homologous recombination ... «BMC Blogs Network, Jul 15»
2
Genome-wide gene–gene interaction analysis for next-generation …
Article | PubMed |; Emanuele MJ, Elia AE, Xu Q et al: Global identification of modular cullin-RING ligase substrates. Cell 2011; 147: 459–474. «Nature.com, Jul 15»
3
Digestion of Nucleic Acids Starts in the Stomach
3c). As shown in Fig. 3c, if a fragment has a 3′-phosphate, its 3′ end will not be ligated to another synthesized oligo-DNA by T4 DNA ligase, ... «Nature.com, Jul 15»
4
Surveying the repair of ancient DNA from bones via high-throughput …
Both methods use endonucleases and glycosylases along with a DNA polymerase-ligase combination. PreCR Repair Mix increases the number of molecules ... «BioTechniques.com, Jul 15»
5
WesternU Researchers Unveil New Mechanism in the Regulation of …
This study shows that a type of SK, the synaptic SK2 channels, are regulated by the E3 ubiquitin ligase UBE3A, whose deficiency results in ... «Benzinga, Jul 15»
6
Not All Dengue Viruses Have Have Same Potential For Disease …
This subgenomic RNA then binds a host protein, TRIM25, which is a E3 ubiquitin ligase that polyubiquitylates RIG-I to amplify and sustain ... «Medical Research News and Interviews on MedicalResearch.com, Jul 15»
7
The proinflammatory role of HECTD2 in innate immunity and …
We discovered a ubiquitin E3 ligase, HECTD2, which ubiquitinated and mediated the degradation of PIAS1, thus increasing inflammation in an experimental ... «Science Magazine, Jul 15»
8
A nonsense variant in HERC1 is associated with intellectual …
HERC1 is an ubiquitin ligase that interacts with tuberous sclerosis complex 2, an upstream negative regulator of the mTOR pathway. Our data ... «Nature.com, Jul 15»
9
Promotion of Endoplasmic Reticulum-Associated Degradation of …
Depletion of particular ERAD-associated isomerases, lectins, and translocon components, including ERAD E3 ubiquitin ligase HRD1, ... «Journal of Virology, Jul 15»
10
Hybrid vigour: Infertility rescue
The male sterility thus induced is rescued in hybrids because TBPm3 is tagged with an additional protein fragment used by the ubiquitin ligase, ... «Nature.com, Jul 15»

REFERENCE
« EDUCALINGO. Ligase [online]. Available <https://educalingo.com/en/dic-en/ligase>. May 2024 ».
Download the educalingo app
en
English dictionary
Discover all that is hidden in the words on
index
a b c d e f g h i j k l m n o p q r s t u v w x y z