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Meaning of "morpholino" in the English dictionary

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DICTIONARY
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ETYMOLOGY OF THE WORD MORPHOLINO

From the organic compound morpholine.
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Etymology is the study of the origin of words and their changes in structure and significance.
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PRONUNCIATION OF MORPHOLINO

morpholino  [ˌmɔːfəʊˈliːnəʊ] play
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GRAMMATICAL CATEGORY OF MORPHOLINO

noun
adjective
verb
adverb
pronoun
preposition
conjunction
determiner
exclamation
Morpholino is a noun.
A noun is a type of word the meaning of which determines reality. Nouns provide the names for all things: people, objects, sensations, feelings, etc.

WHAT DOES MORPHOLINO MEAN IN ENGLISH?

Morpholino

Morpholino, in molecular biology, describes a molecule in a particular structural family that is used to modify gene expression. Morpholino oligomers are a class of antisense, a technology used to block access of other molecules to specific sequences within nucleic acids. Morpholinos block small regions of the base-pairing surfaces of ribonucleic acid. Most Morpholinos are used as research tools for reverse genetics by knocking down gene function. This article discusses only the Morpholino antisense oligos, which are nucleic acid analogs. The word "morpholino" can occur in other chemical names, referring to chemicals containing a six-membered morpholine ring. To help avoid confusion with other morpholine-containing molecules, when describing oligos "Morpholino" is often capitalized as a trade name, though this usage is not consistent throughout the scientific literature. Morpholinos are sometimes referred to as "PMO". Gene knockdown is achieved by preventing cells from making a targeted protein. Morpholinos can also modify the splicing of pre-mRNA.

Definition of morpholino in the English dictionary

The definition of morpholino in the dictionary is a type of molecule used in altering the development of genes by preventing the access of other molecules.

WORDS THAT RHYME WITH MORPHOLINO


Angeleno
ˌændʒəˈliːnəʊ
Angelino
ˌændʒeˈliːnəʊ
Aquino
əˈkiːnəʊ
bambino
bæmˈbiːnəʊ
Barcino
bɑːˈsiːnəʊ
Bardolino
ˌbɑːdəˈliːnəʊ
cappuccino
ˌkæpʊˈtʃiːnəʊ
casino
kəˈsiːnəʊ
Celaeno
sɛˈliːnəʊ
chino
ˈtʃiːnəʊ
Filipino
ˌfɪlɪˈpiːnəʊ
fino
ˈfiːnəʊ
kino
ˈkiːnəʊ
Latino
læˈtiːnəʊ
leno
ˈliːnəʊ
merino
məˈriːnəʊ
Pendolino
ˌpɛndəʊˈliːnəʊ
Reno
ˈriːnəʊ
Valentino
ˌvælənˈtiːnəʊ
vino
ˈviːnəʊ

WORDS THAT BEGIN LIKE MORPHOLINO

morphogen
morphogeneses
morphogenesis
morphogenetic
morphogenic
morphogeny
morphographer
morphography
morphol.
morpholine
morphologic
morphological
morphologically
morphologist
morphology
morphometric
morphometrics
morphometry
morphophoneme
morphophonemic

WORDS THAT END LIKE MORPHOLINO

albino
amino
Calvino
campesino
cassino
dino
domino
ladino
lino
Pacino
palomino
pepino
rhino
San Bernardino
San Marino
Stalino
Ticino
Torino
Trevino
wino

Synonyms and antonyms of morpholino in the English dictionary of synonyms

SYNONYMS

Translation of «morpholino» into 25 languages

TRANSLATOR
online translator

TRANSLATION OF MORPHOLINO

Find out the translation of morpholino to 25 languages with our English multilingual translator.
The translations of morpholino from English to other languages presented in this section have been obtained through automatic statistical translation; where the essential translation unit is the word «morpholino» in English.

Translator English - Chinese

吗啉
1,325 millions of speakers

Translator English - Spanish

morfolino
570 millions of speakers

English

morpholino
510 millions of speakers

Translator English - Hindi

morpholino
380 millions of speakers
ar

Translator English - Arabic

morpholino
280 millions of speakers

Translator English - Russian

морфолино
278 millions of speakers

Translator English - Portuguese

morf
270 millions of speakers

Translator English - Bengali

morpholino
260 millions of speakers

Translator English - French

morpholino
220 millions of speakers

Translator English - Malay

Morpholino
190 millions of speakers

Translator English - German

Morpholino
180 millions of speakers

Translator English - Japanese

モルホリノ
130 millions of speakers

Translator English - Korean

모르 폴리 노
85 millions of speakers

Translator English - Javanese

Morpholino
85 millions of speakers
vi

Translator English - Vietnamese

morpholino
80 millions of speakers

Translator English - Tamil

morpholino
75 millions of speakers

Translator English - Marathi

मॉर्फोलिनो
75 millions of speakers

Translator English - Turkish

morfolino
70 millions of speakers

Translator English - Italian

morpholino
65 millions of speakers

Translator English - Polish

morfolino
50 millions of speakers

Translator English - Ukrainian

морфоліно
40 millions of speakers

Translator English - Romanian

morfolino
30 millions of speakers
el

Translator English - Greek

μορφολινο-
15 millions of speakers
af

Translator English - Afrikaans

morpholino
14 millions of speakers
sv

Translator English - Swedish

morfolino
10 millions of speakers
no

Translator English - Norwegian

morfolino-
5 millions of speakers

Trends of use of morpholino

TRENDS

TENDENCIES OF USE OF THE TERM «MORPHOLINO»

The term «morpholino» is quite widely used and occupies the 48.886 position in our list of most widely used terms in the English dictionary.
0
100%
FREQUENCY
Quite widely used
77
/100
The map shown above gives the frequency of use of the term «morpholino» in the different countries.
Principal search tendencies and common uses of morpholino
List of principal searches undertaken by users to access our English online dictionary and most widely used expressions with the word «morpholino».

FREQUENCY OF USE OF THE TERM «MORPHOLINO» OVER TIME

The graph expresses the annual evolution of the frequency of use of the word «morpholino» during the past 500 years. Its implementation is based on analysing how often the term «morpholino» appears in digitalised printed sources in English between the year 1500 and the present day.

Examples of use in the English literature, quotes and news about morpholino

EXAMPLES

10 ENGLISH BOOKS RELATING TO «MORPHOLINO»

Discover the use of morpholino in the following bibliographical selection. Books relating to morpholino and brief extracts from same to provide context of its use in English literature.
1
Inhibition of Flaviviruses by Antisense Morpholino Oligomers
Tia Shanatta Deas. Table of Contents Acknowledgements ii List of Figures and Tables vii Frequently-used Abbreviations ix Abstract x Chapter I: Introduction 1 Chapter II: General Materials & Methods 11 Chapter III: Inhibition of Flavivirus ...
Tia Shanatta Deas, 2008
2
Fish Development and Genetics: The Zebrafish and Medaka Models
Subsequently, delivery agents such as ethoxylated polyethylenimine (EPEI) have been modified using DNA as a carrier bridge for morpholino loading and effective delivery in tissue culture cells.21 Delivery agents such as lipofectin and ...
‎2004
3
Development of Sea Urchins, Ascidians, and Other ...
Since a signal above background can be detected when 100-fold fewer copies of GFP mRNA are injected (our unpublished observations), the morpholino effectively blocked greater than 99% of the translation of GFP mRNA. No adverse  ...
Charles A. Ettensohn, Gregory A. Wray, Gary M. Wessel, 2004
4
Progress in Drug Metabolism
Morpholino doxorubicin is an analogue of the anthracycline drug doxorubicin (8, Figure 5), the use of which is limited by ... for derivatives superior to doxorubicin a series of anthracyclines with morpholino and cyanomorpholino moieties were ...
G. G. Gibson, 1992
5
Therapeutic Oligonucleotides
Morpholino synthesis begins with an activated and base-protected subunit being attached through its 50-end to a functionalized solid support. The oligo synthesis proceeds opposite to the direction used for standard nucleic acid synthesis, ...
Jens Kurreck, 2008
6
Cilia: Model Organisms and Intraflagellar Transport: Model ...
Final design of a morpholino can be done in consultation with the manufacturer, Gene Tools LLC (http://www.gene-tools.com/). For a control morpholino, we also design an “invert sense” oligo. These have the same purine/ pyrimidine ratio as ...
‎2009
7
The Chemistry of Heterocyclic Compounds, Thiophene and Its ...
... R5 Thiophene (%) CéHs Morpholino CH3, CH3 p-NOQC6H,1 81 CfiH 5 Morpholino —(CH 2) ,,— CH 3CO 5 3 CfiH5 Morpholino CH3, CH3 C6H5CO 92 C6115 Morpholino —(CH,)S— CGHSCO 78 CEH5 Morpholino CH3, C611S CEHSCO ...
Salo Gronowitz, 2009
8
Report of Committee on Drug Addiction, 1929-1941 and ...
National Research Council (U.S.). Committee on drug addiction. 21 22 23 84 25 26 87 88 29 80 81 88 88 34 80 36 87 38 39 40 Derivatives of 1,2,3,4- tetrahydrophenanthrene 2-Morpholino- 1-keto-' -Hydrochloride 2-Morpholino-l- hydroxy-(A)* ...
National Research Council (U.S.). Committee on drug addiction, 1941
9
Enamines: Synthesis: Structure, and Reactions, Second Edition,
Synthesis: Structure, and Reactions, Second Edition, Gilbert Cook. 1- ( N - Morpholino) - 1 , 3-butadiene , reaction with, a-chloro- acrylonitrile, 368 2- (N - Morpholino) -l,3-diphenyl- propene , reaction with , tosyl azide, 226 2-(N- Morpholino)- ...
Gilbert Cook, 1987
10
The Chemistry of Heterocyclic Compounds, Chemistry of 1 2 ...
OC, Hs 4-Morpholino 4-Morpho1in0 25 7-258 337, 338 0C, H5 4-Morpho1ino 4- Morpho1ino 242-243 338/337 SH 4-M0rpholino 4-Morpholino 2494253 (taut.) 337, 338 SC, H5 4-Morpholino 4-Morpholino 2377239 337, 338 SCH, C6 H5 ...
Hans Neunhoeffer, Paul F. Wiley, 2009

10 NEWS ITEMS WHICH INCLUDE THE TERM «MORPHOLINO»

Find out what the national and international press are talking about and how the term morpholino is used in the context of the following news items.
1
Public Release: 22-Jul-2015 Antiviral compound protects nonhuman …
... a class of antisense compounds known as phosphorodiamidate morpholino oligomers (or PMOs), according to senior author and USAMRIID ... «EurekAlert, Jul 15»
2
FDA Sets Review Dates for Muscular Dystrophy Drugs
Eteplirsen uses phosphorodiamidate morpholino oligomer (PMO)-based chemistry and proprietary exon-skipping technology to skip exon 51 of ... «P&T Community, Jul 15»
3
A biosynthetic pathway for a prominent class of microbiota-derived …
... Spectrum Labs) against 500 mL of extraction buffer (10 mM 3-(N-morpholino)propanesulfonic acid (MOPS) and 300 mM NaCl, adjusted to pH 7.0 with NaOH) ... «Nature.com, Jul 15»
4
Current Trade Stocks Highlights: Sarepta Therapeutics (NASDAQ …
Its lead product candidate is Eteplirsen, an antisense phosphorodiamidate morpholino oligomer therapeutic, which is in Phase III clinical ... «wsnewspublishers, Jul 15»
5
Immune response and insulin signalling alter mosquito feeding …
Immediately prior to feeding, morpholino solutions were warmed in a water bath at 37 °C for 10 min. Vivo-morpholino standard control targeting ... «Nature.com, Jul 15»
6
AAV-mediated RLBP1 gene therapy improves the rate of dark …
... gel in 3-(N-morpholino)propanesulfonic acid buffer (Life Technologies). Proteins were transferred to polyvinyl difluoride membranes using an ... «Nature.com, Jul 15»
7
Subetta increases phosphorylation of insulin receptor β-subunit …
NuPage (4–12%) Bis-Tris polyacrylamide gels (catalog number NP0323Box), MOPS buffer (3-(N-morpholino)propanesulfonic acid; catalog ... «Nature.com, Jul 15»
8
NASDAQ Stocks to Track: Synaptics, (NASDAQ:SYNA), RADA …
Its lead product candidate is Eteplirsen, an antisense phosphorodiamidate morpholino oligomer therapeutic, which is in Phase III clinical ... «wsnewspublishers, Jul 15»
9
Low-bias phosphopeptide enrichment from scarce samples using …
The gel electrophoresis was performed at 50 V for 15 min in MOPS (AppliChem) buffer [50 mM 3-(N-morpholino)propanesulfonic acid (MOPS), ... «Nature.com, Jul 15»
10
Small Cap Stocks Alert: Sarepta Therapeutics (SRPT), Organovo …
Its lead product candidate is Eteplirsen, an antisense phosphorodiamidate morpholino oligomer therapeutic, which is in Phase III clinical ... «Techsonian, Jul 15»

REFERENCE
« EDUCALINGO. Morpholino [online]. Available <https://educalingo.com/en/dic-en/morpholino>. Apr 2024 ».
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