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Meaning of "PKU" in the English dictionary

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PRONUNCIATION OF PKU

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WHAT DOES PKU MEAN IN ENGLISH?

PKU

Phenylketonuria

Phenylketonuria is an autosomal recessive metabolic genetic disorder characterized by homozygous or compound heterozygous mutations in the gene for the hepatic enzyme phenylalanine hydroxylase, rendering it nonfunctional.:541 This enzyme is necessary to metabolize the amino acid phenylalanine to the amino acid tyrosine. When PAH activity is reduced, phenylalanine accumulates and is converted into phenylpyruvate, which can be detected in the urine. Untreated PKU can lead to intellectual disability, seizures, and other serious medical problems. The mainstream treatment for classic PKU patients is a strict PHE-restricted diet supplemented by a medical formula containing amino acids and other nutrients. In the United States, the current recommendation is that the PKU diet should be maintained for life. Patients who are diagnosed early and maintain a strict diet can have a normal life span with normal mental development. However, recent research suggests that neurocognitive, psychosocial, quality of life, growth, nutrition, bone pathology are slightly suboptimal if diet is not supplemented with amino acids.

Definition of PKU in the English dictionary

The definition of PKU in the dictionary is phenylketonuria.

WORDS THAT BEGIN LIKE PKU

PJs
pk
pkg.
pkgs
pkt
pl
Pl.
PL/1
PLA

Synonyms and antonyms of PKU in the English dictionary of synonyms

SYNONYMS

Translation of «PKU» into 25 languages

TRANSLATOR
online translator

TRANSLATION OF PKU

Find out the translation of PKU to 25 languages with our English multilingual translator.
The translations of PKU from English to other languages presented in this section have been obtained through automatic statistical translation; where the essential translation unit is the word «PKU» in English.

Translator English - Chinese

北大
1,325 millions of speakers

Translator English - Spanish

PKU
570 millions of speakers

English

PKU
510 millions of speakers

Translator English - Hindi

पीकेयू
380 millions of speakers
ar

Translator English - Arabic

PKU
280 millions of speakers

Translator English - Russian

ФКУ
278 millions of speakers

Translator English - Portuguese

PKU
270 millions of speakers

Translator English - Bengali

PKU
260 millions of speakers

Translator English - French

PCU
220 millions of speakers

Translator English - Malay

PKU
190 millions of speakers

Translator English - German

PKU
180 millions of speakers

Translator English - Japanese

PKU
130 millions of speakers

Translator English - Korean

PKU
85 millions of speakers

Translator English - Javanese

PKU
85 millions of speakers
vi

Translator English - Vietnamese

PKU
80 millions of speakers

Translator English - Tamil

நிலையான PKU
75 millions of speakers

Translator English - Marathi

पीकेयू
75 millions of speakers

Translator English - Turkish

PKU
70 millions of speakers

Translator English - Italian

PKU
65 millions of speakers

Translator English - Polish

PKU
50 millions of speakers

Translator English - Ukrainian

ФКУ
40 millions of speakers

Translator English - Romanian

PKU
30 millions of speakers
el

Translator English - Greek

PKU
15 millions of speakers
af

Translator English - Afrikaans

PKU
14 millions of speakers
sv

Translator English - Swedish

PKU
10 millions of speakers
no

Translator English - Norwegian

PKU
5 millions of speakers

Trends of use of PKU

TRENDS

TENDENCIES OF USE OF THE TERM «PKU»

The term «PKU» is quite widely used and occupies the 35.434 position in our list of most widely used terms in the English dictionary.
0
100%
FREQUENCY
Quite widely used
84
/100
The map shown above gives the frequency of use of the term «PKU» in the different countries.
Principal search tendencies and common uses of PKU
List of principal searches undertaken by users to access our English online dictionary and most widely used expressions with the word «PKU».

FREQUENCY OF USE OF THE TERM «PKU» OVER TIME

The graph expresses the annual evolution of the frequency of use of the word «PKU» during the past 500 years. Its implementation is based on analysing how often the term «PKU» appears in digitalised printed sources in English between the year 1500 and the present day.

Examples of use in the English literature, quotes and news about PKU

EXAMPLES

10 ENGLISH BOOKS RELATING TO «PKU»

Discover the use of PKU in the following bibliographical selection. Books relating to PKU and brief extracts from same to provide context of its use in English literature.
1
Pku Mom
A TRUE STORY OF A MOTHER LOVE AND DEVOTION TO HER CHILDREN. COVERING 40 YEARS OF THIS DISORDER AND PROBEMS FACED BY A CAREGIVER THAT WILL MAKE YOU WEEPTAKEN FROM THE RADIO PROGRAM AND AUDIO BOOK " SLEEP WITH THE ANGELS, PAUL."
Carole ANNE MURPHY, 2008
2
Penny the Penguin Has Pku
Phenylketonuria (pronounced fee-nill-key-toe-NURR-ee-uh) or PKU is a rare, inherited metabolic disorder.
Laurie Bernstein, Joanna Helm, 2012
3
Low Protein Cookery for Phenylketonuria
The nutrient calculations in this edition of the cookbook are based on the updated 1995 Low Protein Food List for PKU compiled by the author, which is the most widely used food list for the PKU diet in the United States.
Virginia E. Schuett, 1997
4
Low Protein Food List for PKU
This third edition contains over 6,000 entries, the most extensive listing yet of foods that are potentially suitable for the diet, nearly double the number found in the previous edition.
Virginia E. Schuett, 2010
5
Robert Guthrie--the PKU Story: A Crusade Against Mental ...
This marvelous history tells of Robert Guthrie's campaign to discover and promote world-wide newborn testing for PKU anomalies plus a host of other genetic disorders that cause mental retardation or premature death if not treated ...
Jean Koch, 1997
6
The PKU Paradox: A Short History of a Genetic Disease
The study of PKU promises to help uncover the causes of other hereditary disorders, particularly the basis for other types of mental deficiency.”37 After noting that fewer than five hundred individuals with PKU are born in the United States each ...
Diane B. Paul, Jeffrey P. Brosco, 2013
7
Guide to Clinical Preventive Services: Report of the U.S. ...
Recommendation: Screening for phenylketonuria (PKU) is recommended for all newborns prior to discharge from the nursery. Infants who are tested before 24 hours of age should receive a repeat screening test before the third week of life.
‎1989
8
Inborn Metabolic Diseases: Diagnosis and Treatment
17.3.1 Clinical Presentation Although it was recognised that the offspring born to mothers with PKU are at risk of damage from the teratogenic effects of PHE over 40 years ago [33], it was not until the publication of the seminal paper by Lenke ...
John Fernandes, Jean-Marie Saudubray, Georges van den Berghe, 2006
9
Pediatric Nutrition in Chronic Diseases and Developmental ...
Phenylketonuria (PKU) may be the most thoroughly studied inherited metabolic disorder, a disorder in which the consequences can be multigenerational and can have significantly different outcomes. A neonate may be born with PKU or may ...
Shirley Ekvall, Valli K. Ekvall, 2005
10
Education of Students with an Intellectual Disability: ...
An example of an inborn metabolic error that, if untreated, leads to intellectual disability and other behavioral problems is phenylketonuria (PKU) , which is an autosomal recessive disorder and can occur when both parents have a recessive  ...
Phil Foreman, 2009

10 NEWS ITEMS WHICH INCLUDE THE TERM «PKU»

Find out what the national and international press are talking about and how the term PKU is used in the context of the following news items.
1
BioMarin Joins the NASDAQ-100 Index
... Kuvan® (sapropterin dihydrochloride) Powder for Oral Solution and Tablets, for phenylketonuria (PKU), developed in partnership with Merck ... «GlobeNewswire, Jul 15»
2
Company Shares of BioMarin Pharmaceutical Inc. Drops by -2.75%
... for the treatment of phenylketonuria (PKU), and BMN-701, an enzyme replacement therapy for Pompe disease, a glycogen storage disorder. «Insider Trading Report, Jul 15»
3
Annual basketball friendly between Chinese and Taiwanese …
PKU were the Asian university basketball champions last year. Two players - one from each team - were taken to hospital for X-rays, but were ... «South China Morning Post, Jul 15»
4
Friday's Trade Stocks Roundup: MGIC Investment (NYSE:MTG …
... proprietary synthetic oral form of 6R-BH4 used to treat patients with phenylketonuria (PKU), an inherited metabolic disease; Aldurazyme used ... «wsnewspublishers, Jul 15»
5
Explore phenylketonuria global clinical trials review for 2014
Clinical trial report, “Phenylketonuria (PKU) Global Clinical Trials Review, H1, 2014″ provides data on the Phenylketonuria (PKU) clinical trial ... «WhaTech, Jul 15»
6
China stocks higher at close of trade; Shanghai Composite up 0.66%
... (SZ:002309) which lost 10.00% to settle at 30.05 and PKU HealthCare Corp Ltd (SZ:000788) which was down 9.99% to 18.65 at the close. «Investing.com, Jul 15»
7
Merck Receives EU-Approval to Extend Kuvan Use to Children with …
PKU is a rare disease with significant consequences – but if managed appropriately, it doesn't have to impair child development or quality of ... «PipelineReview.com, Jul 15»
8
This Orphan Drugmaker Deserves a Spot on Your Radar
Kuvan helps to treat phenylketonuria, or PKU,which afflicts about one of every 15,000 infants in the United States and inhibitsthe patient's ability ... «Fox Business, Jul 15»
9
BRIEF-PKU Healthcare withdraws application for assets acquisition …
July 8 PKU Healthcare Corp Ltd. * Says withdraws application for assets acquisition plan. Source text in Chinese: bit.ly/1LWbXjT. «Reuters, Jul 15»
10
Shields students and staff raise awareness of phenylketonuria
Shields Elementary School students and staff wanted to raise awareness of phenylketonuria. PKU is an inborn error of metabolism involving ... «Cape Gazette, Jul 15»

REFERENCE
« EDUCALINGO. Pku [online]. Available <https://educalingo.com/en/dic-en/pku>. Apr 2024 ».
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