10 ENGLISH BOOKS RELATING TO «SURAMIN»
Discover the use of
suramin in the following bibliographical selection. Books relating to
suramin and brief extracts from same to provide context of its use in English literature.
1
Encyclopedia of Parasitology: A-M
The basic properties of the trypanosomal glycolytic enzymes resulting in
additional positive charges on their surfaces may facilitate the binding of the
highly negatively charged suramin. Thus, there are likely to be potentiated
inhibitory effects ...
2
The Antimicrobial Drugs
Renal dysfunction is also a frequent complication of high-dose therapy with the
anticancer drug methotrexate, which is also a potent inhibitor of mammalian
dihydrofolate reductase.1*1 Suramin Suramin is a compound developed from a
group ...
Eric M. Scholar Associate Professor of Pharmacology University of Nebraska College of Medicine, William B. Pratt Professor of Pharmacology University of Michigan Medical School, 2000
3
Mass Spectrometry in Cancer Research
Suramin:Albumin ratio (moles) -87,995 80,850 -73,705 -67,989 Mass, Da
FIGURE 5.31 The number of suramin molecules bound to albumin and the
molecular masses of the complexes at various suramimalbumin molar ratios.
highest number ...
4
Antimicrobial Drug Resistance: Mechanisms of Drug ...
The compound was first clinically tested against human sleeping sickness in
1921 and has stayed the drug of choice against East African T. rhodesiense
infections ever since. Suramin (Fig. 1) has a very long elimination half-life (44–54
days), ...
21.2. Suramin. Pharmacology PHYSICO-CHEMICAL PROPERTIES Suramin is a
polysulphonated naphthyl urea that is strongly negatively charged at
physiological pH. Its molecular weight is 1297 g/mol (acid) and 1429 g/mol (
sodium salt).
Ian Maudlin, P. H. Holmes, Michael A. Miles, 2004
6
Antiangiogenic Cancer Therapy
suramin as the agent showed activity in HIV associated malignancies such as
Kaposi's Sarcoma and Non-Hodgkins lymphoma. Suramin's antitumor and
antiangiogenic effects are thought, in part, to relate to the binding of the agent to
a ...
Darren W. Davis, Roy S. Herbst, James L. Abbruzzese, 2007
7
Trends in Prostate Cancer Research
In a subsequent trial, Eisenberger et al [46] used suramin in three cohorts of
patients achieving three increasing target plasma concentrations within the
overall range of 100-300 ng/ml. Overall, 40 of 67 assessable patients (60%) had
a 50% ...
8
Radioprotectors: Chemical, Biological, and Clinical Perspectives
5 lnhibition of spontaneous and radiation- induced DNA fragmentation by
suramin. Cells detached from the tissue culture flasks were collected 48 h after
various treatments, treated with proteinase K and RNAse and analyzed by
agarose gel ...
Edward A. Bump, Kamal Malaker, 1997
9
Proceedings of First Symposium on New World Trypanosomes
Since the disease is probably restricted to domestic livestock and no stage of
development is found in the insect vector(s). any successful control programme is
likely to have permanent effects. Chemotherapy of surra relies on suramin,
quinap ...
10
Twelth Annual Meeting of the European Orthopaedic Research ...
SURAMIN AFFECTS HUMAN OSTEOSARCOMA CELLS Trieb K. & Blahovec H.
Department of Orthopedics, University of Vienna, A- 1090 Vienna, Austria,
klemens.triebfajakh-wien.ac.at Keywords: suramin, osteosarcoma, proliferation, ...
10 NEWS ITEMS WHICH INCLUDE THE TERM «SURAMIN»
Find out what the national and international press are talking about and how the term
suramin is used in the context of the following news items.
Clinical Trial in San Diego - African Sleeping Sickness treatment …
San Diego,CA – A new study to test whether African Sleeping Sickness treatment suramin can treat autism is about to be completed at the University of ... «Autism Daily Newscast, Jun 15»
100-Year-Old Drug Suramin Under Investigation As Autism Treatment
The drug, suramin (Germanin), was created in 1916 for the treatment of a type of a human sleep sickness known as African trypanosomiasis that is caused by a ... «Psychiatry Advisor, Jun 15»
San Diego Autism Researchers Are Testing A New Use For An Old …
Researchers are recruiting 20 patients to see if a drug called suramin — which has been used to treat African sleeping sickness since the early 20th century ... «KPBS, Jun 15»
UC San Diego researchers launch clinical trial to evaluate safety …
The phase 1 clinical trial, which is recruiting 20 qualifying participants, will evaluate suramin -- a century-old drug still used for African sleeping sickness -- as a ... «News-Medical.net, Jun 15»
Terima Bantuan Pembaca KR, Suramin Berobat Kembali
TEMANGGUNG (KRjogja.com) - Bantuan pembaca Kedaulatan Rakyat sebesar Rp 4.888.000 diserahkan pada pemderita tumor usus, Suramin (47) warga ... «Kedaulatan Rakyat, May 15»
Reversing Autism Considering Its Main Causes
American scientists introduced drugs that could reverse autism in mice. Suramin was previously used to cure African sleeping disease, but its new application in ... «Doctor Tipster, Apr 15»
Autism Research: January 23, 2015 Week in Review
The drug, suramin, is an anti-purinergic, i.e. it acts by blocking a cell's response to danger, allowing them to return back to normal networking and ... «Autism Daily Newscast, Jan 15»
Spotted: Suramin surprise; film under fire
An antimicrobial drug called suramin improves behavior in a mouse model of fragile X syndrome, according to a study published last week in Molecular Autism. «SFARI News, Jan 15»
Anti-parasitic Drug Found To Reverse Autism-like Symptoms In Mice
Using suramin, an antimicrobial drug first developed to treat trypanosomiasis, also known as “African Sleeping Sickness,” in 1916, Dr. Naviaux's group observed ... «The UCSD Guardian Online, Jan 15»
NeuroBreak: Football Concussions Down, Phineas Gage Redux
The antiparasitic drug suramin reduced autism-like symptoms in a mouse model of fragile X disorder. Roche is getting serious about spinal muscular atrophy, ... «MedPage Today, Jan 15»
