10 ENGLISH BOOKS RELATING TO «VALPROATE»
Discover the use of
valproate in the following bibliographical selection. Books relating to
valproate and brief extracts from same to provide context of its use in English literature.
In this book, emphasis is placed on the scientific background leading to the discovery of valproate and its clinical development into one of the most widely and successfully used antiepileptic drugs, a real milestone in drug therapy.
2
The Maudsley Prescribing Guidelines
Valproate is available in the UK in three forms: sodium valproate (Epilim) and
valproic acid (Convulex), licensed for the treatment of epilepsy, and semi- sodium
valproate (Depakote), licensed for the acute treatment of mania. Both
semisodium ...
David Taylor, Carol Paton, Robert Kerwin, 2007
3
Status Epilepticus: Mechanisms and Management
Valproate. Introduction. An anticonvulsant used in the management of status
epilep- ticus (SE) should be easy to administer, have a quick onset and a long
duration of action, and have a good safety and toler- ability profile. An
intravenous (IV) ...
Claude G. Wasterlain, David M. Treiman, 2006
4
The American Psychiatric Publishing Textbook of ...
Thus, free fraction concentrations of valproate in serum can be increased and
valproate toxicity can be precipitated by coadministration of other highly protein-
bound drugs (e.g., aspirin) that can displace valproate from its protein-binding
sites.
Alan F. Schatzberg, Charles B. Nemeroff, 2009
5
Essential Psychopharmacology: The Prescriber's Guide. ...
Abilify (aripiprazole), 7 Absenor (valproate), 95 Aclonium (gabapentin), 31
Alemoxan (clozapine), 19 Aleviatin (zonisamide), 107 Alti-Valproic (valproate),
95 amisulpride, 1 Amizepin (carbamazepine), 13 Apilepsin (valproate), ...
6
Foye's Principles of Medicinal Chemistry
Topiramate can also decrease the effectiveness of oral contraceptives. C O OH
C O OH C OH Valproic acid (dipropylacetic acid) (E)-2-ene-valproic acid 4-ene-
valproic acid VALPROIC ACID AND ITS DERIVATIVES O Valproate is available
as ...
Thomas L. Lemke, David A. Williams, 2012
7
A Clinical Guide to Epileptic Syndromes and their Treatment
However, this GABAergic action is observed only at high valproate levels and
may explain its efficacy in other, but not absence, seizures. GABAergic drugs that
affect GABAB receptors have a pro-absence action because they potentiate ...
C. P. Panayiotopoulos, 2010
8
Side Effects of Drugs Annual: A worldwide yearly survey of ...
cohort was restricted to the 6584 children who were born to women with epilepsy,
the absolute risk of autism spectrum disorder among 432 children exposed to
valproate was 4.2% (95% CI 1⁄4 2.2, 7.8; adjusted HR 1⁄4 1.7; 95% CI 1⁄4 0.9, 3.2
) ...
9
Mania: Clinical and Research Perspectives
Serum concentrations of valproate are obtained 12 hours after the last dose (
through levels) every 2-4 days and should be maintained between 50 and 125
ug/mL. Once an optimal dose has been achieved, the total daily dose may be
given at ...
10
Manual of Clinical Psychopharmacology
Low-dose valproate has been successfully used to treat cyclothymia (Jacobsen
1993). Some case reports and open-label studies have suggested that valproate
may be useful in treating panic disorder, particularly when the disorder is ...
Alan F. Schatzberg, Jonathan O. Cole, Charles DeBattista, 2010
10 NEWS ITEMS WHICH INCLUDE THE TERM «VALPROATE»
Find out what the national and international press are talking about and how the term
valproate is used in the context of the following news items.
Roxane Says Jazz's Xyrem Patent Covers Law Of Nature
Valproate reportedly has an additive effect on GHB, the active ingredient in Xyrem, which means patients who are taking valproate should take a lower dose of ... «Law360, Apr 15»
Epilim/Sodium Valproate Zentiva gastro-resistant tablets odour …
The smell has been described as 'fishy', 'sweaty armpits' and 'cannabis'. The manufacturer Sanofi has now investigated, and the source of the smell has been ... «Epilepsy Action, Mar 15»
Doctors in new warning about epilepsy drug valproate
Results of a Europe-wide review of the epilepsy drug valproate, known to cause birth defects, has resulted in the Government sending strengthened warnings to ... «Epilepsy Society, Jan 15»
Women taking valproate should be told about risks of developmental …
Women taking valproate should be told about the risks of developmental disorders in children exposed to the drug during pregnancy, says the UK medicines ... «The Pharmaceutical Journal, Jan 15»
EU Strengthens Warnings on Valproate Use in Women
The CMDh, a European regulatory body representing EU member states, has moved to strengthen warnings on the anticonvulsant valproate (Depacon, AbbVie ... «Medscape, Nov 14»
Prenatal exposure to sodium valproate linked to lower IQ in offspring
HealthDay News -- Prenatal exposure to sodium valproate (VPA) is associated with a reduction in offspring IQ, according to research published in The Cochrane ... «Clinical Advisor, Oct 14»
Restrict Valproate, EMA Committee Urges
This is because of the risk for malformations and developmental problems in children exposed to valproate during pregnancy. The committee recommends that ... «Medscape, Oct 14»
Drug nightmare for mums
Sodium valproate - trade name Epilim - is an anti-epileptic drug also used for other conditions such as bipolar disorder, pain and migraines. It has been ... «Stuff.co.nz, Oct 14»
Concerns with using sodium valproate to treat epilepsy in pregnant …
Using sodium valproate during pregnancy can put babies at risk of developmental problems. Kalliopi Dodou and Paul Whiteley explore some of the recent ... «The Pharmaceutical Journal, Jul 14»
The Limitless Drug: What If It Were Possible to Learn Any New Skill …
In both tests, those who took the Valproate scored “much higher” in pitch identification accuracy, the implication being that it is possible to learn a complex skill ... «Pacific Standard, Jul 14»
