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Meaning of "zymogen" in the English dictionary

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DICTIONARY
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PRONUNCIATION OF ZYMOGEN

zymogen  [ˈzaɪməʊˌdʒɛn] play
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GRAMMATICAL CATEGORY OF ZYMOGEN

noun
adjective
verb
adverb
pronoun
preposition
conjunction
determiner
exclamation
Zymogen is a noun.
A noun is a type of word the meaning of which determines reality. Nouns provide the names for all things: people, objects, sensations, feelings, etc.

WHAT DOES ZYMOGEN MEAN IN ENGLISH?

Zymogen

A zymogen is an inactive enzyme precursor. A zymogen requires a biochemical change for it to become an active enzyme. The biochemical change usually occurs in a lysosome where a specific part of the precursor enzyme is cleaved in order to activate it. The inactivating piece which is cleaved off can be a peptide unit, or can be independently folding domains comprising more than 100 residues. Although they limit the enzyme's ability, these n-terminal extensions of the enzyme or a “prosegment” often aid in the stabilizing and folding of the enzyme they inhibit. The pancreas secretes zymogens partly to prevent the enzymes from digesting proteins in the cells in which they are synthesised. Enzymes like pepsin are created in the form of pepsinogen, an inactive zymogen. Pepsinogen is activated when chief cells release it into HCl which partially activates it. Another partially activated pepsinogen completes the activation by removing the peptide turning the pepsinogen into pepsin. Accidental activation of zymogens can happen when the secretion duct in the pancreas is blocked by a gallstone resulting in acute pancreatitis.

Definition of zymogen in the English dictionary

The definition of zymogen in the dictionary is any of a group of compounds that are inactive precursors of enzymes and are activated by a kinase.

WORDS THAT RHYME WITH ZYMOGEN


aesthesiogen
iːsˈθiːzɪəˌdʒɛn
allergen
ˈæləˌdʒɛn
chalcogen
ˈkælkəˌdʒɛn
dictyogen
ˈdɪktɪəˌdʒɛn
electrogen
ɪˈlɛktrəʊˌdʒɛn
endogen
ˈɛndəʊˌdʒɛn
gen
dʒɛn
hallucinogen
həˈluːsɪnəˌdʒɛn
halogen
ˈhæləˌdʒɛn
histogen
ˈhɪstəˌdʒɛn
ionogen
aɪˈɒnəˌdʒɛn
Jingdezhen
ˈdʒɪŋˈdɛdʒɛn
lucigen
ˈluːsɪˌdʒɛn
Origen
ˈɒrɪˌdʒɛn
pathogen
ˈpæθəˌdʒɛn
phytopathogen
ˌfaɪtəʊˈpæθədʒɛn
pyrogen
ˈpaɪrəʊˌdʒɛn
thrombogen
ˈθrɒmbəˌdʒɛn

WORDS THAT BEGIN LIKE ZYMOGEN

zymite
zymogeneses
zymogenesis
zymogenic
zymogram
zymoid
zymologic
zymological
zymologist
zymology
zymolysis
zymolytic
zymome
zymometer
zymosan
zymoses
zymosimeter
zymosis
zymotechnic
zymotechnical

WORDS THAT END LIKE ZYMOGEN

adaptogen
androgen
carcinogen
chromogen
cryogen
cyanogen
estrogen
fibrinogen
glycogen
hogen
humogen
hydrogen
kerogen
leucaemogen
liquid nitrogen
mitogen
nitrogen
oestrogen
plasminogen
progestogen

Synonyms and antonyms of zymogen in the English dictionary of synonyms

SYNONYMS

Translation of «zymogen» into 25 languages

TRANSLATOR
online translator

TRANSLATION OF ZYMOGEN

Find out the translation of zymogen to 25 languages with our English multilingual translator.
The translations of zymogen from English to other languages presented in this section have been obtained through automatic statistical translation; where the essential translation unit is the word «zymogen» in English.

Translator English - Chinese

酶原
1,325 millions of speakers

Translator English - Spanish

zimógeno
570 millions of speakers

English

zymogen
510 millions of speakers

Translator English - Hindi

zymogen
380 millions of speakers
ar

Translator English - Arabic

زايموجين
280 millions of speakers

Translator English - Russian

зимоген
278 millions of speakers

Translator English - Portuguese

zymogen
270 millions of speakers

Translator English - Bengali

zymogen
260 millions of speakers

Translator English - French

zymogène
220 millions of speakers

Translator English - Malay

Zymogen
190 millions of speakers

Translator English - German

Zymogen
180 millions of speakers

Translator English - Japanese

チモーゲン
130 millions of speakers

Translator English - Korean

발효균
85 millions of speakers

Translator English - Javanese

Zymogen
85 millions of speakers
vi

Translator English - Vietnamese

zymogen
80 millions of speakers

Translator English - Tamil

zymogen
75 millions of speakers

Translator English - Marathi

जॅमोऑन
75 millions of speakers

Translator English - Turkish

zimojen
70 millions of speakers

Translator English - Italian

zimogeno
65 millions of speakers

Translator English - Polish

zymogen
50 millions of speakers

Translator English - Ukrainian

зимоген
40 millions of speakers

Translator English - Romanian

zimogen
30 millions of speakers
el

Translator English - Greek

zymogen
15 millions of speakers
af

Translator English - Afrikaans

zymogen
14 millions of speakers
sv

Translator English - Swedish

zymogen
10 millions of speakers
no

Translator English - Norwegian

zymogenplasminogen.Plasminogen
5 millions of speakers

Trends of use of zymogen

TRENDS

TENDENCIES OF USE OF THE TERM «ZYMOGEN»

The term «zymogen» is regularly used and occupies the 90.516 position in our list of most widely used terms in the English dictionary.
0
100%
FREQUENCY
Regularly used
58
/100
The map shown above gives the frequency of use of the term «zymogen» in the different countries.
Principal search tendencies and common uses of zymogen
List of principal searches undertaken by users to access our English online dictionary and most widely used expressions with the word «zymogen».

FREQUENCY OF USE OF THE TERM «ZYMOGEN» OVER TIME

The graph expresses the annual evolution of the frequency of use of the word «zymogen» during the past 500 years. Its implementation is based on analysing how often the term «zymogen» appears in digitalised printed sources in English between the year 1500 and the present day.

Examples of use in the English literature, quotes and news about zymogen

EXAMPLES

10 ENGLISH BOOKS RELATING TO «ZYMOGEN»

Discover the use of zymogen in the following bibliographical selection. Books relating to zymogen and brief extracts from same to provide context of its use in English literature.
1
Plasminogen: Structure, Activation, and Regulation: ...
that is, the active protease of each zymogen/protease pair can activate the zymogen of the other protease/zymogen pair. Once proteolytic activity is present in a system of two such zymogens their reciprocal activation will result in the ...
David M. Waisman, 2003
2
Functional Ultrastructure: Atlas of Tissue Biology and Pathology
Discharge of the granule content occurs under precise local requirements after external, either neuronal or hormonal, stimulation. The micrographs in panels A and B show mature secretory granules, the zymogen granules (ZG), in the apical  ...
Margit Pavelka, Jürgen Roth, 2010
3
The Enzymes
Proteinase produced by the action of trypsin on the zymogen is stable at —20° for at least 2 years without loss of activity. Both the zymogen and the enzyme are unstable at pH values below 4.5 and above 9.5 (3). They are denatured by ...
Paul D. Boyer, 1971
4
Surgical Pathology of the GI Tract, Liver, Biliary Tract, ...
35-43). The cytoplasm is moderate to focally abundant and characteristically shows eosinophilic granularity in the apical region due to aggregates of zymogen granules, although in some cases, granules are difficult to appreciate histologically.
Robert D. Odze, John R. Goldblum, 2009
5
The Exocrine Pancreas: Normal and Abnormal Functions
fraction from guinea pig, which contained six times as much RNA as that of the dog zymogen granule fraction. It is probable that the lower phospholipid and RNA content of the dog zymogen granule fraction reflects a purer preparation rather ...
CIBA Foundation Symposium, 2009
6
CURRENT TOPICS IN DEVELOPMNTL BIOLOGY
In insects, stable mRNA was shown for adult cuticular protein synthesis in Tenebrio (Ilan and Quastel, 1966; Ilan, 1968, 1969b; Ilan et al., 1970) and for cocoonase in differentiating zymogen cells of the glia gland of the silk moth ( Kafatos and ...
A. A. Moscona, Alberto Monroy, 1976
7
Textbook of Small Animal Surgery
After stimulation (e.g., feeding and cholecystokinin secretion), mature zymogen granules and their contents are released from the cell into the ductal lumen in a process of membrane fusion and exocytosis. 6. Finally, zymogens are activated ...
Douglas H. Slatter, 2003
8
Proteinase and Peptidase Inhibition: Recent Potential ...
MMP zymogen activation requires proteinase cleavage of the pro-domain, thereby destabilizing the cysteine-zinc interaction (Springman et al 1990). Following the initial proteolytic event, the zymogen undergoes further inter- or intra-molecular ...
H. John Smith, Claire Simons, 2003
9
Hydrolysis: Peptide Bonds
This, in the later stage of growth, is transformed into the active enzyme by an autocatalytic reaction initiated by the slight proteolytic activity shown by zymogen reduced through contact with -SH groups in the bacterial cell walls (4). Cell wall - SH ...
Paul D. Boyer, 1971
10
Secretion: Mechanisms and Control
Manchester University Press, 1984 42 Ultrastructural Patterns of Pancreatic Zymogen and Fluid Secretion. Relevance to Cystic Fibrosis Jeanette Blomfield and Peter J. Settree SUMMARY The ultrastructural patterns of the stimulated rat ...
Richard Maynard Case, Jennifer M. Lingard, John Atherton Young, 1984

10 NEWS ITEMS WHICH INCLUDE THE TERM «ZYMOGEN»

Find out what the national and international press are talking about and how the term zymogen is used in the context of the following news items.
1
A novel caspase 8 selective small molecule potentiates TRAIL …
Heterodimerization constrains the active site of zymogen caspase 8 into a productive ... Pro-caspase 8, an inactive precursor or zymogen, undergoes major ... «Nature.com, May 15»
2
Editorial: Pro-matrix metalloproteinase-9 in tumor B lymphocytes …
In most cancers, MMP-9 is secreted as 92 kDa-inactive zymogen (pro-MMP-9) [2, 3]. Much effort has gone into understanding how pro-MMP-9 contributes to ... «Journal of Leukocyte Biology, Jul 14»
3
כיצד נקרש הדם בגוף?
לפני שהתרומבין הופך לפעיל, הוא זורם במחזור הדם שלנו בצורתו הבלתי-פעילה (zymogen) המכונה בשם פרו-תרומבין (טרום-תרומבין). כאשר יש צורך באנזים הפעיל (לאחר פציעה של ... «הידען, Jul 14»
4
Removing parts of shape-shifting protein explains how blood clots
Before thrombin becomes active, it circulates throughout the blood in the inactive (zymogen) form called prothrombin. When the active enzyme is needed (after a ... «R & D Magazine, Jul 14»
5
콧데, 여드름 피부전용 선크림 출시
현재 출시된 여드름 피부전용 선크림은 발효·효소화장품 자이모겐(www.zymogen.co.kr)과 유기농화장품 오썸(www.organicsum.com)에서 판매중이며, 판매사 ... «뉴스와이어, Mar 14»
6
施一公研究组连发Nature,JBC文章解密分子奥
在“Proteolytic Processing of Caspase-9 Zymogen Is Required for Apoptosome-mediated Activation of Caspase-9”这篇文章中,研究人员发现了蛋白酶caspases ... «生物通, Apr 13»
7
Animal Doctor: Small-plate dining is best for cats
Have your veterinarian prescribe Zymogen, which will help reduce inflammation and possible bacterial and/or fungal infection. You are not feeding your cat ... «Washington Post, Jan 13»
8
Animal Doctor
Good nutrition rich in omega-3 fatty acids helps, as does a zymogen enzyme-based cleaner or diluted apple cider vinegar and olive oil applied after drying the ... «Washington Post, Jan 13»
9
Protein Build-Up Could Mean Crohn's
These proteins, called zymogen glycoprotein-2 or GP-2, fight other proteins in the person's body. When these proteins are present in a part of the body, ... «dailyRx, Dec 12»
10
Cura de ingrasare rapida - ce mananci, ce bei, ce sport faci
... neplăcute. Enzimele favorizează digestia şi ajută corpul să extragă cât mai mulţi nutrienţi din alimente. Poţi încerca Triferment, Zymogen, Panzcebil, etc. «Unica.ro, Nov 11»

REFERENCE
« EDUCALINGO. Zymogen [online]. Available <https://educalingo.com/en/dic-en/zymogen>. Apr 2024 ».
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