10 PORTUGUESE BOOKS RELATING TO «DICUMAROL»
Discover the use of
dicumarol in the following bibliographical selection. Books relating to
dicumarol and brief extracts from same to provide context of its use in Portuguese literature.
1
Pharmaceutical Achievers: The Human Face of Pharmaceutical ...
This hemorrhagic agent — 3,3'-methylene bis-(4-hydroxycoumarin) — was later
named "dicumarol." Dicumarol is formed naturally when coumarin oxidizes and
combines with other substances present in moldy hay. Link also demonstrated ...
Mary Ellen Bowden, Amy Beth Crow, Tracy Sullivan, 2003
2
Blackwell's Five-Minute Veterinary Consult: Equine
When cut and baled for hay under high-moisture conditions, various molds
metabolize coumarin to form dicumarol, which inhibits vitamin K epoxide
reductase, in turn decreasing vitamin K] formation and leading to decreased
prothrombin ...
Jean-Pierre Lavoie, Kenneth Hinchcliff, 2011
3
Veterinary Pharmacology and Therapeutics
Of the several coumarin derivatives, bishydroxycoumarin (Dicumarol, USP) was
the first oral anticoagulant and 3-(0L-acetonylbenzyl)4-hydroxycoumarin (
Warfarin Sodium, USP; Panwarfin, Coumodin) was the second compound used.
Jim E. Riviere, Mark G. Papich, 2013
4
2010 Nurse's Drug Handbook
dicumarol. Class and Category Chemical class: Coumarin derivative Therapeutic
class: Anticoagulant Pregnancy category: X Indications and Dosages ® To
prevent and treat pulmonary embolus, thromboembolus, and venous thrombus; ...
& Bartlett Jones, Jones and Bartlett Publishers, 2009
If PT or INR are prolonged, withhold one dicumarol dose, as prescribed, and, to
reverse anticoagulation, give vitamin K. If patient has severe bleeding, expect to
give blood to offset vitamin K's delayed onset. • Assess patient for signs of ...
Jones and Bartlett Publishers, 2008
6
Drug Interactions in Psychiatry
No consistent effect on warfarin elimination was observed. A similar protocol was
followed with dicumarol, 200 mg and 300 mg doses. Inconsistent effects were
observed on dicumarol metabolism, with a suggestion that dicumarol absorption
...
Its analysis showed it to be dicumarol, a compound that results when a coumarin
molecule is linked to another coumarin molecule by an enzyme present in the
fungus that causes hay mold. The requirement of the fungal enzyme for this ...
Stanley Fields, Mark Johnston, 2010
8
Applied Pharmacokinetics & Pharmacodynamics: Principles of ...
O O = CH, OH Nature 4-Hydroxycoumarin Warfarin Figure 28-1 Synthesis
pathways for the coumarin anticoagulants, dicumarol and warfarin. Dicumarol
was first isolated from spoiled sweet clover. Warfarin is a synthetic compound
initially ...
9
Oxidative Stress in Cancer Biology and Therapy
The effects of streptonigrin were reversed in pancreatic cancer cells pretreated
with dicumarol, a known inhibitor of NQO1. Another potential strategy to exploit in
pancreatic cancer is the fact that cancer cells demonstrate increased intracellular
...
Douglas R. Spitz, Kenneth J. Dornfeld, Koyamangalath Krishnan, 2011
10
Blockbuster Drugs: The Rise and Decline of the ...
He then immediately set out to synthesize the same compound, later named
dicumarol, and accomplished the feat on April fool's day, 1940. Dr. Huebner was
nobody's fool; the compound he pre- pared behaved identically in every way to
the ...
10 NEWS ITEMS WHICH INCLUDE THE TERM «DICUMAROL»
Find out what the national and international press are talking about and how the term
dicumarol is used in the context of the following news items.
En Jalisco, policías interceptan cargamento ilegal de cigarrillos
... cialis pour les femmes ou si le saignement se produit, l'action de la dicumarol peut administrer par voie intraveineuse contrecarré la vitamine prix cialis france ... «UnomásUno, Oct 15»
Semarnat inicia investigación científica sobre la vaquita marina
Dicumarol peut administré pour la thrombose cérébrale oral le prix de viagra en algerie cialis generique lilly jelly kamagra problèmes kamagra oral jelly en ... «UnomásUno, Oct 15»
Slippery Slope: Does Convenience Trump Safety With NOACs?
From the rancid hay, UW biochemist Karl Paul Link was able to isolate a chemical anticoagulant known as dicumarol. UW patented the research under the name ... «MedPage Today, Aug 15»
Is Aspirin a Dangerous Drug?
They found also that dicumarol could be qualitatively degraded to salicylic acid. ... K after the production of hemorrhage by dicumarol or salicylic acid, however, ... «JAMA: The Journal of the American Medical Association, Dec 14»
Bazı bitkiler ilaçların etkisini bozar
Dicumarol karaciğerde Vitamin K'nın aktivitesini inhibe edebilir ve potansiyel olarak koağülasyonun uzamasına yol açabilir. DOZ AYARINA DİKKAT! «Sabah, Jun 14»
Sweet clovers
“The toxic factor is dicumarol, which is formed from coumarin only when the sweet clover is spoiled by certain kinds of mold. Poisoning is more likely from hay ... «Michigan State University Extension, Jul 13»
How dead cattle led to the discovery of warfarin
In the article 'The Discovery of Dicumarol and Its Sequels' for the American Heart Association journal Circulation, the chemist Dr Karl Paul Link describes his ... «PMLiVE, Jun 13»
Farmer, sick herd and persistent UW scientist results in warfarin
Based on this knowledge, they developed a drug called Dicumarol that was tested by doctors in St. Paul and elsewhere to see if it could prevent blood clots in ... «Pioneer Press, Oct 11»
Innovation marks UW-Madison contribution to vitamins, drugs …
In 1941, Karl Paul Link discovered dicumarol, an anti-coagulant and poison. From dicumarol, Link synthesized coumadin (Warfarin), the first widely effective rat ... «University of Wisconsin-Madison, Jul 11»
Alvadásgátlás: csak óvatosan!
A tényleges okot 1939-ben fedezték fel, azonosítva a növényben található bishydroxycoumarint, (dicumarol), később ennek számos változatát sikerült előállítani. «Weborvos, Oct 06»
