PALABRAS DEL INGLÉS RELACIONADAS CON «SPHINGOSINE»
sphingosine
kinase
inhibitor
phosphate
receptor
sigma
antibody
modulator
backbone
cancer
sphingosine
carbon
amino
alcohol
with
unsaturated
hydrocarbon
chain
which
forms
primary
part
sphingolipids
class
cell
membrane
lipids
pubchem
long
derivative
sphinganine
major
bases
mammals
merriam
webster
found
especially
nervous
tissue
membranes
origin
greek
sphingos
structure
occurrence
biosynthesis
zwitterionic
lysophospholipid
cellular
metabolite
derived
from
ceramide
synthesized
avanti
polar
sphingolipid
signalling
lipid
animal
cells
also
been
metacyc
biocyc
enigmatic
article
most
emerging
vital
mediator
receptors
tocris
bioscience
view
high
purity
products
active
leading
worldwide
supplier
performance
life
powder
aldrich
10 LIBROS DEL INGLÉS RELACIONADOS CON «SPHINGOSINE»
Descubre el uso de
sphingosine en la siguiente selección bibliográfica. Libros relacionados con
sphingosine y pequeños extractos de los mismos para contextualizar su uso en la literatura.
1
Different Approaches of Teaching in Chemistry. Membrane ...
Mattie, M., Brooker, G., Spiegel, S.: Sphingosine-l-phospate, a putative second
messenger, mobilizes calcium from internal stores via an inositol trisphosphate-
independent pathway. J. Biol. Chem. 269 (5): 3181-8, 1994. 12. Lee, M. J. ...
2
IKACh and
Sphingosine 1-phosphate Signaling in the Heart
Sphingosine-1 -phosphate (SIP) is a product of sphingomyelin metabolism that
binds with nanomolar affinity to five members of a family of G protein coupled
receptors (S 1 P1-5) [160, 161]. SIP has been implicated in cell proliferation, ...
Maria Isabel Roman Alonso, 2006
3
Sphingolipids as Signaling and Regulatory Molecules
(Dihydro)ceramide synthase 1 regulated sensitivity to cisplatin is associated with
the activation of p38 mitogen-activated protein kinase and is abrogated by
sphingosine kinase 1. Mol Cancer Res 2007; 5:801-812. 41. Sankala HM, Hait
NC, ...
Charles Chalfant, Maurizio Del Poeta, 2011
4
Sphingosine 1-phosphate Receptor 2 in Vascular Homeostasis
Chapter III Sphingosine 1 -phosphate receptor 2 promotes atherosclerosis
through caspase-11 inflammasome component 3.1.1 Atherogenesis
Atherosclerosis a major human disease that contributes to 77 Sphingosine 1-
phosphate receptor 2 ...
5
Part I: Discovery of
Sphingosine 1-phosphate Receptor Type-1 ...
Abstract Part 1 Sphingosine-1-phosphate (S1P) is a signaling lipid molecule
which acts both as an intracellular mediator and an extracellular ligand for
specific cell surface receptors to regulate cellular condition and physiological
processes.
6
Lipid Mediators and Their Metabolism in the Brain
Sphingosine is an 18-carbon amino alcohol with an unsaturated hydrocarbon
chain. It is found in sphingolipids (cerbroside, sulfatide, and ganglioside) as well
as phospholipid (sphingomyelin) (Fig. 9.1). Sphingomyelin (SM) is the major ...
acyl chain (at any desired position in the molecule) as well as carbons 1-3 of the
sphingosine base, which form the interfacial region of the sphingomyelin
molecules in bilayers and lipoproteins (see sections 4a, 4b). The complete
chemical ...
John Nigel Hawthorne, 1982
8
General, Organic, and Biological Chemistry
The double bond present in the sphingosine carbon chain is a trans double bond
. When sphingolipids were discovered over a century ago by the physician–
chemist Johann Thudichum (1829–1901), their biochemical role seemed as ...
9
TEXTBOOK OF BIOCHEMISTRY AND HUMAN BIOLOGY
A. Biosynthesis of Sphingosine The initial step in the biosynthesis of glycolipids is
the formation of sphingosine. Earlier work from various laboratories has shown
that one of the precursors of sphingosine is serine and the other is palmitic acid.
G. P. TALWAR, L .M. SRIVASTAVA, 2002
10
Encyclopedia of Molecular Pharmacology
Deficiency of either SphKl or SphK2 in mice does not cause obvious
abnormalities, while double knockout mice die during embryogenesis. These
data suggest that despite opposing functions the two sphingosine kinase
isoenzymes can ...
10 NOTICIAS EN LAS QUE SE INCLUYE EL TÉRMINO «SPHINGOSINE»
Conoce de qué se habla en los medios de comunicación nacionales e internacionales y cómo se emplea el término
sphingosine en el contexto de las siguientes noticias.
Cortisone affects acute lung injury (ALI) via pro-inflammatory …
In the case of ALI, dexamethasone leads to an increase of sphingosine-1-phosphate and, consequently, to a strengthening of the vessel walls' barrier function. «Medical Xpress, Jul 15»
Celgene Buys Receptos. Is Arena Pharmaceuticals Next?
Sphingosine 1-phosphate 1, or S1P1, receptor is expressed on white blood cells, also called lymphocytes, and signaling of the receptor by S1P promotes the ... «Motley Fool, Jul 15»
Lipid Enzyme Heightens Insulin Sensitivity and Shows Promise as …
Excess ceramide was converted into sphingosine, another lipid byproduct. Both ceramide and sphingosine are energy sources, but the two lipids have contrary ... «Newswise, Jul 15»
RedHill Biopharma Initiates Phase I/II Study of ABC294640 for …
SK2 is an innovative molecular target for anti-cancer therapy because of its critical role in catalyzing the formation of the lipid-signaling molecule sphingosine ... «Nasdaq, Jun 15»
Sphingosine 1-Phosphate Type 1 (S1P-1) Receptor Agonists …
DelveInsight's, Sphingosine 1-Phosphate Type 1 (S1P-1) Receptor Agonists- Pipeline Insights, 2015, provides the in-depth analysis of the pipeline assets ... «PR Newswire, Jun 15»
Akaal Pharma Receives Approval to Initiate Phase 2 Clinical Trial for …
AKP-11 is a novel First-in-Class topical Sphingosine 1-Phosphate receptor-1 (S1P1) modulator for the treatment of mild-to-moderate plaque psoriasis in patients ... «Business Wire, Jun 15»
Receptos Announces Oral Plenary Presentation of TOUCHSTONE …
Ozanimod is a novel, oral, once daily, selective sphingosine 1-phosphate 1 and 5 receptor modulator in development for autoimmune indications including ... «GlobeNewswire, May 15»
RedHill Biopharma Acquires Phase II First-in-Class Oral Small …
ABC294640 is a proprietary, first-in-class, orally-administered sphingosine kinase-2 (SK2) inhibitor, with anti-inflammatory and anti-cancer activities, targeting ... «GlobeNewswire, Mar 15»
Akaal Pharma Announces Positive Results from Phase 1 Clinical …
AKP-11 is a novel, potent and highly selective sphingosine 1-phosphate receptor subtype-1 (S1P1) modulator undergoing clinical development for topical ... «VentureBeat, Feb 15»
Arena's APD334 Has Real Blockbuster Potential (ARNA)
APD334, sphingosine 1-phosphate (S1P) subtype 1 receptor modulator, is safer than the only approved S1P product, Gilenya. It also displayed impressive ... «Seeking Alpha, Ene 15»
