PALABRAS DEL INGLÉS RELACIONADAS CON «SURAMIN»
suramin
sigma
mechanism
action
trypanosomiasis
autism
african
sleeping
sickness
side
effects
clinical
trials
prostate
cancer
suramin
drug
developed
oskar
dressel
richard
kothe
bayer
germany
still
sold
under
brand
name
germanin
lack
response
patients
with
aids
related
spec
complex
kaplan
wolfe
volberding
injection
route
drugs
supplements
mayo
clinic
used
treatment
river
blindness
onchocerciasis
infections
caused
drugbank
from
evaluations
annual
been
shown
have
potent
antineoplastic
properties
manufactured
advanced
patient
information
detailed
includes
common
descriptions
warnings
dosing
hexasodium
salt
supplier
tocris
bioscience
view
high
purity
leading
worldwide
performance
life
science
reagents
medscape
reference
indication
specific
sodium
frequency
based
adverse
comprehensive
interactions
contraindications
polysulphonated
naphthylurea
potential
activity
blocks
binding
various
growth
factors
including
insulin
like
santa
cruz
biotech
uncouples
proteins
receptors
blocking
their
interaction
intracellular
purinergic
receptor
domains
compound
calbiochem
millipore
enzo
sciences
10 LIBROS DEL INGLÉS RELACIONADOS CON «SURAMIN»
Descubre el uso de
suramin en la siguiente selección bibliográfica. Libros relacionados con
suramin y pequeños extractos de los mismos para contextualizar su uso en la literatura.
1
Encyclopedia of Parasitology: A-M
The basic properties of the trypanosomal glycolytic enzymes resulting in
additional positive charges on their surfaces may facilitate the binding of the
highly negatively charged suramin. Thus, there are likely to be potentiated
inhibitory effects ...
2
The Antimicrobial Drugs
Renal dysfunction is also a frequent complication of high-dose therapy with the
anticancer drug methotrexate, which is also a potent inhibitor of mammalian
dihydrofolate reductase.1*1 Suramin Suramin is a compound developed from a
group ...
Eric M. Scholar Associate Professor of Pharmacology University of Nebraska College of Medicine, William B. Pratt Professor of Pharmacology University of Michigan Medical School, 2000
3
Mass Spectrometry in Cancer Research
Suramin:Albumin ratio (moles) -87,995 80,850 -73,705 -67,989 Mass, Da
FIGURE 5.31 The number of suramin molecules bound to albumin and the
molecular masses of the complexes at various suramimalbumin molar ratios.
highest number ...
4
Antimicrobial Drug Resistance: Mechanisms of Drug ...
The compound was first clinically tested against human sleeping sickness in
1921 and has stayed the drug of choice against East African T. rhodesiense
infections ever since. Suramin (Fig. 1) has a very long elimination half-life (44–54
days), ...
21.2. Suramin. Pharmacology PHYSICO-CHEMICAL PROPERTIES Suramin is a
polysulphonated naphthyl urea that is strongly negatively charged at
physiological pH. Its molecular weight is 1297 g/mol (acid) and 1429 g/mol (
sodium salt).
Ian Maudlin, P. H. Holmes, Michael A. Miles, 2004
6
Antiangiogenic Cancer Therapy
suramin as the agent showed activity in HIV associated malignancies such as
Kaposi's Sarcoma and Non-Hodgkins lymphoma. Suramin's antitumor and
antiangiogenic effects are thought, in part, to relate to the binding of the agent to
a ...
Darren W. Davis, Roy S. Herbst, James L. Abbruzzese, 2007
7
Trends in Prostate Cancer Research
In a subsequent trial, Eisenberger et al [46] used suramin in three cohorts of
patients achieving three increasing target plasma concentrations within the
overall range of 100-300 ng/ml. Overall, 40 of 67 assessable patients (60%) had
a 50% ...
8
Radioprotectors: Chemical, Biological, and Clinical Perspectives
5 lnhibition of spontaneous and radiation- induced DNA fragmentation by
suramin. Cells detached from the tissue culture flasks were collected 48 h after
various treatments, treated with proteinase K and RNAse and analyzed by
agarose gel ...
Edward A. Bump, Kamal Malaker, 1997
9
Proceedings of First Symposium on New World Trypanosomes
Since the disease is probably restricted to domestic livestock and no stage of
development is found in the insect vector(s). any successful control programme is
likely to have permanent effects. Chemotherapy of surra relies on suramin,
quinap ...
10
Twelth Annual Meeting of the European Orthopaedic Research ...
SURAMIN AFFECTS HUMAN OSTEOSARCOMA CELLS Trieb K. & Blahovec H.
Department of Orthopedics, University of Vienna, A- 1090 Vienna, Austria,
klemens.triebfajakh-wien.ac.at Keywords: suramin, osteosarcoma, proliferation, ...
10 NOTICIAS EN LAS QUE SE INCLUYE EL TÉRMINO «SURAMIN»
Conoce de qué se habla en los medios de comunicación nacionales e internacionales y cómo se emplea el término
suramin en el contexto de las siguientes noticias.
Clinical Trial in San Diego - African Sleeping Sickness treatment …
San Diego,CA – A new study to test whether African Sleeping Sickness treatment suramin can treat autism is about to be completed at the University of ... «Autism Daily Newscast, Jun 15»
100-Year-Old Drug Suramin Under Investigation As Autism Treatment
The drug, suramin (Germanin), was created in 1916 for the treatment of a type of a human sleep sickness known as African trypanosomiasis that is caused by a ... «Psychiatry Advisor, Jun 15»
San Diego Autism Researchers Are Testing A New Use For An Old …
Researchers are recruiting 20 patients to see if a drug called suramin — which has been used to treat African sleeping sickness since the early 20th century ... «KPBS, Jun 15»
UC San Diego researchers launch clinical trial to evaluate safety …
The phase 1 clinical trial, which is recruiting 20 qualifying participants, will evaluate suramin -- a century-old drug still used for African sleeping sickness -- as a ... «News-Medical.net, Jun 15»
Terima Bantuan Pembaca KR, Suramin Berobat Kembali
TEMANGGUNG (KRjogja.com) - Bantuan pembaca Kedaulatan Rakyat sebesar Rp 4.888.000 diserahkan pada pemderita tumor usus, Suramin (47) warga ... «Kedaulatan Rakyat, May 15»
Reversing Autism Considering Its Main Causes
American scientists introduced drugs that could reverse autism in mice. Suramin was previously used to cure African sleeping disease, but its new application in ... «Doctor Tipster, Abr 15»
Autism Research: January 23, 2015 Week in Review
The drug, suramin, is an anti-purinergic, i.e. it acts by blocking a cell's response to danger, allowing them to return back to normal networking and ... «Autism Daily Newscast, Ene 15»
Spotted: Suramin surprise; film under fire
An antimicrobial drug called suramin improves behavior in a mouse model of fragile X syndrome, according to a study published last week in Molecular Autism. «SFARI News, Ene 15»
Anti-parasitic Drug Found To Reverse Autism-like Symptoms In Mice
Using suramin, an antimicrobial drug first developed to treat trypanosomiasis, also known as “African Sleeping Sickness,” in 1916, Dr. Naviaux's group observed ... «The UCSD Guardian Online, Ene 15»
NeuroBreak: Football Concussions Down, Phineas Gage Redux
The antiparasitic drug suramin reduced autism-like symptoms in a mouse model of fragile X disorder. Roche is getting serious about spinal muscular atrophy, ... «MedPage Today, Ene 15»
