MOTS EN ANGLAIS EN RAPPORT AVEC «DYSTROPHIN»
dystrophin
costamere
disease
glycoprotein
complex
what
does
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gene
function
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uniprot
component
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becker
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10 LIVRES EN ANGLAIS EN RAPPORT AVEC «DYSTROPHIN»
Découvrez l'usage de
dystrophin dans la sélection bibliographique suivante. Des livres en rapport avec
dystrophin et de courts extraits de ceux-ci pour replacer dans son contexte son utilisation littéraire.
1
Dystrophin: Gene, Protein, and Cell Biology
This book is concerned with advances in research on dystrophin, and how its absence gives rise to muscular dystrophy.
Susan C. Brown, Jack A. Lucy, 1997
Dystrophin is a large structural protein in close association to glycoproteins in the
plasma membrane of normal myotubes or myofibers. The dystrophin/
glycoproteins complex provides support to the cell membrane cytoskeleton.
Unlike the mdx ...
3
Neuromuscular Diseases During Development
Dystrophin is completely or almost completely absent from the muscles of DMD
patients, and is already absent in affected foetuses. No patients lacking
dystrophin have ever been reported with a clinical phenoiypc other than DMD.
Fernando Cornelio, Giovanni Lanzi, Ermellina Fedrizzi, 1997
4
Theory and Practice of Histological Techniques
Both Duchenne and Becker muscular dystrophies are now known to result from
mutations in the dystrophin gene, and together are referred to as '
dystrophinopathies'. The dystrophin gene is a very large gene (3 mega- bases of
DNA), ...
John D. Bancroft, Marilyn Gamble, 2008
5
Encyclopedia of Genetics
Figure 2 Transcript (A) and protein (B) maps of the dystrophin gene. The
transcript map (A) shows the approximate location of the 79 exons and the
position of the five different cell-type specific expression promoters, namely the C
(cortical), ...
Eric C. R. Reeve, Isobel Black, 2001
6
The Molecular and Genetic Basis of Neurologic and ...
It is difficult to prove causality of missense mutations because there is no defined
functional test for mutant dystrophin proteins. Biochemistry Dystrophin was found
to be associated with the plasma membrane both by subcellular fractionation ...
7
Identification and Characterization of Novel Binding ...
INTRODUCTION: Dystrophin Duchenne muscular dystrophy (DMD) is an X-
linked, lethal muscle wasting disorder that is caused by mutations resulting in
absent or non-functional dystrophin protein (Hoffman et al., 1987). The dystrophin
gene ...
Jill Louise Humston, 2008
8
Disorders of Voluntary Muscle
Deletion of as much as 50% of the dystrophin gene can still be compatible with a
relatively mild clinical phenotype; a patient with a deletion of exons 17-51 (68%
of the rod domain) still shows normal localization of the dystrophin-associated ...
George Karpati, David Hilton-Jones, Robert C. Griggs, 2001
9
Gene and Cell Therapy: Therapeutic Mechanisms and ...
The first challenge is that the dystrophin gene is the largest known gene with a
full-length cDNA that is 14kb. However, dystrophin can retain significant function
even when missing large portions of its sequence. Large, in- frame deletions in
the ...
Nancy Smyth Templeton, 2008
They have named the missing protein "dystrophin". According to Kay Davies of
the John Radcliffe Hospital in Oxford, "the lack of dystrophin seems to act like a
time bomb, causing some sort of gradual non- regeneration of fibres". Kunkel and
...
10 ACTUALITÉS CONTENANT LE TERME «DYSTROPHIN»
Découvrez de quoi on parle dans les médias nationaux et internationaux et comment le terme
dystrophin est employé dans le contexte des actualités suivantes.
NHS Refuses Translarna For The Treatment of Duchenne Muscular …
... by progressive muscle degeneration and weakness and is caused by an absence of dystrophin, a protein that helps keep muscle cells intact. «Muscular Dystrophy News, juil 15»
Disease modeling and lentiviral gene transfer in patient-specific …
Filareto et al. showed that they have generated pluripotent stem cell from tip tail fibroblast of mice lacking both dystrophin and utrophin and ... «Nature.com, juil 15»
What Propelled Sarepta Therapeutics' Stock 19% Higher in June?
Eteplirsen is an exon-51 skipping RNA-interference drug designed to increase production of dystrophin, the sheath that surrounds and protects ... «Motley Fool, juil 15»
Biotech Stock News (SRPT) (JUNO) (CELG) (AGTC) (VRTX)
Eteplirsen is a drug that is able to restore the body into being able to produce dystrophin levels once again thus in turn restoring proper muscle ... «CNA Finance, juil 15»
The Race To Cure Duchenne Muscular Dystrophy - An Investor's …
It is caused by an absence of dystrophin, which is an essential protein in muscle cells. Symptoms generally start to manifest in young boys as ... «Seeking Alpha, juil 15»
Summit Therapeutics adds Europe to patent list for key compound
Summit's compound regulates utrophin - a protein - to compensate for the lack of dystrophin that is at the root of DMD. Share. Facebook; Twitter · Google+ ... «Proactive Investors UK, juil 15»
Pre-Market News Alert on: Unum Group (NYSE:UNM), Marriott …
Drisapersen induces the skipping of dystrophin exon 51, potentially providing a therapeutic benefit to DMD patients for whom skipping of exon ... «wsnewspublishers, juil 15»
Genetic Therapeutic Strategies for Duchenne Muscular Dystrophy
DMD is an inherited disorder caused by a defective gene called dystrophin. It is characterized by a rapid progressive skeletal muscle weakness ... «Muscular Dystrophy News, juil 15»
ENZ, LMNX Settle Suit, VSAR Regains Velocity, CATB Hits A High
... 18 ambulatory boys between ages 4 and 7 with a genetically confirmed diagnosis of DMD, regardless of the specific dystrophin mutation. «Nasdaq, juil 15»
LOOK: Man with rare illness graduates cum laude from UP Los Banos
According to the Muscular Dystrophy Association (MDA), DMD is caused by an absence of dystrophin, a protein responsible for keeping ... «ABS CBN News, juil 15»
