«PRODRUG»に関連する英語の本
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prodrugの使いかたを見つけましょう。
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1
Hydrolysis in Drug and
Prodrug Metabolism
Bernard Testa’s fundamental knowledge of this field and his commitment to clear conceptualization and precise language make this book, sadly delayed by the untimely death of Joachim Moyer, another important addition to his contributions ...
Bernard Testa, Joachim M. Mayer, 2003
2
Application of Peptide-Based
Prodrug Chemistry in Drug ...
This is because it stimulates insulin only when the blood glucose level is high thereby reducing the risk of hypoglycemia (a significant disadvantage of using insulin is that an insulin overdose is the single most potent cause of life ...
3
Prodrugs: challenges and rewards. P. 1
oral prodrug delivery is that there are multiple barriers, or potential sites of
metabolism, in series. It is not unusual that a prodrug does not completely pass
through the intestines and liver intact, because the intestines and liver generally
have ...
Valentino J. Stella, 2007
4
Engineering an All Human Component Antibody Enzyme
Prodrug ...
We have successfully developed an ADEPT that is comprised of all human components (hDM-C6MH3B1). hDM, unlike the wild type enzyme is capable of cleaving the relatively non-toxic F-dAdo to its cytotoxic metabolite F-Ade, causing tumor cell ...
5
Current Pharmaceutical Design
One approach which may allow further substantial improvements in the efficacy
of cancer chemotherapy, especially against the common solid tumors, is the
selective activation of prodrug forms of antiproliferative agents. Prodrugs can be ...
6
Preclinical Development Handbook: ADME and Biopharmaceutical ...
Although there is no universal definition for a prodrug itself, and the definition
may vary, generally prodrugs can be defined as pharmacologically inert chemical
derivatives that can be converted in vivo to active drug molecules, enzymatically
or ...
7
Hypoxia Inducible Factor- Targeted Anticancer
Prodrug
3. SPECIFIC. AIMS. Cancer is the second leading cause of death in the United
States. The treatments include chemotherapy, often used in combination with
surgery and radiation therapy. The ultimate success of chemotherapy is limited
by the ...
8
Drug Discovery Handbook
17.5 PHARMACEUTICAL APPLICATIONS OF THE PRODRUG STRATEGY 752
Improved Drug Absorption 752 Improved Aqueous Solubility 766 Prolonged
Duration of Action 769 Improved Drug Targeting 770 Improved Formulation and ...
9
Current Pharmaceutical Design
were 1680-fold and 60-fold higher than their corresponding parent peptides,
respectively [120,121]. A Coumarin-based Esterase-sensitive Prodrug System
Recently, our laboratory has developed a novel coumarin- based prodrug system
for ...
10
Optimizing the "Drug-Like" Properties of Leads in Drug Discovery
Parenteral formulations of poorly soluble drugs can present some unique
challenges to prodrug scientists. First, solubilities greater than 10 mg/ml are often
needed, thus for truly poorly soluble parent drugs, orders of magnitude increases
in ...
Ronald Borchardt, Edward Kerns, Michael Hageman, 2007
用語«PRODRUG»を含むニュース項目
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Pharmacyte Biotech Inc (OTCMKTS:PMCB) Updates On Second …
Pharmacyte's treatment administers low dosage of the prodrug ifosfamide along with Cell-in-a-Box® capsules. These unique capsules contain ... «Journal Transcript, 7月 15»
Celator® Pharmaceuticals to Present on Fixed-Ratio …
... docetaxel prodrug nanoparticle formulation), being studied by the National Cancer Institute's Nanotechnology Characterization Laboratory. «PR Newswire, 7月 15»
Vistagen Therapeutics's "Buy" Rating Reiterated at Chardan Capital …
AV-101 is an orally-available, non-sedating, prodrug candidate for neurological diseases. Receive News & Ratings for Vistagen Therapeutics Daily - Enter your ... «Dakota Financial News, 7月 15»
Company Shares of Threshold Pharmaceuticals, Inc. Drops by -5.66%
The Companys hypoxia activated prodrug product candidates, including TH-302, are designed to specifically target the hypoxic microenvironment of tumors by ... «OTC Outlook, 7月 15»
Ascendis Pharma A/S's Lock-Up Period To End Tomorrow …
The Company is engaged in applying its TransCon technology to develop a pipeline of long-acting prodrug therapies that address markets with ... «Mideast Time, 7月 15»
KemPharm Receives Consensus Recommendation of "Strong Buy …
The Company, through its Ligand Activated Therapy (LAT) platform technology, creates NME prodrug product candidates. The Company's NME prodrug product ... «Dakota Financial News, 7月 15»
Celgene May Also Want to Take Notice of PharmaCyte Biotech
The encapsulation technology is made up of genetically modified live cells that are capable of activating a chemotherapy prodrug in the case of ... «MarketWatch, 7月 15»
Basilea announces that CHMP recommends approval of …
Isavuconazole is an azole antifungal and the active agent of the prodrug isavuconazonium sulfate. Basilea is co-developing the drug with ... «Benzinga, 7月 15»
Insmed Downgraded by Zacks (INSM)
Insmed is also focused on the development of INS1009, the company's inhaled treprostinil prodrug for the treatment of pulmonary arterial ... «WKRB News, 7月 15»
Prodrug Delivers Estrogen Just To The Brain
Estrogen levels drop in the brains of women who have gone through menopause or had surgeries to remove their ovaries. This hormone ... «The Biological SCENE, 7月 15»
