«URATE»に関連する英語の本
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1
Clinical Biochemistry: An Illustrated Colour Text
At physiological hydrogen ion concentration, uric acid is mostly ionized and
present in plasma as sodium urate (Fig. 1). An elevated serum urate
concentration is known as hyperuricaemia. Uric acid and urate are relatively
insoluble molecules ...
Michael J. Stewart, James Shepherd, Allan Gaw, 2011
2
Diseases of the Kidney and Urinary Tract
In most mammals uric acid is further oxidized to allantoin by the hepatic enzyme,
urate oxidase (uricase). However, during early hominoid evolution (12 to 20
million years ago) a series of mutations occurred, first affecting the promoter
region ...
3
Primer on the Rheumatic Diseases
CAUSES OF HYPERURICEMIA AND URATE-LOWERING AGENTS. Causes of
hyperuricemia Uric acid overproduction Inherited enzyme defects HGRT
deficiency, PRPP synthetase overactivity Increased cell turnover
Myeloproliferative and ...
John H. Klippel, John H. Stone, L eslie J. Crofford, 2008
4
Genetic Diseases of the Kidney
vesicles, urate/chloride anion exchanger was demonstrated (Kahn et al 1985).
This urate/chloride anion exchanger at the basolateral membrane was not
inhibited by PAH and lactate. Since urate transport by human OAT1 was inhibited
by ...
Richard P. Lifton, Stefan Somlo, Gerhard H. Giebisch, 2009
5
Principles and Practice of Endocrinology and Metabolism
Subcutaneous tophi may ulcerate and drain urate crystals and, rarely, become
secondarily infected. Tophi in the interstitium of the kidney may lead to fibrosis
and mild renal insufficiency, a condition referred to as urate nephropathy. Urate
salts ...
6
Therapy of Renal Diseases and Related Disorders
Therefore, one may stabilize the gouty patient with anti- inflammatory agents prior
to prescribing agents that lower the serum urate (96). Colchicine, 0.5-0. 6 mg
once or twice daily, usually is effective at preventing attacks of gouty arthritis
during ...
Wadi N. Suki, Shaul G. Massry, 1991
Urate oxidasc does not contain or require an organic cofactor or a transition
metal in order to be catalytically active. The reaction catalyzed by the enzyme is
the conversion of urate into 5-bydroxytsourate, not allamoin as is often reported.
Perry A. Frey, Dexter B. Northrop, 1999
8
Clinical Chemistry: an overview ; [proceedings of the 13th ...
Decreased urate excretion Genetic Causes Enzyme defects and mutations
Glucose - 6 -phosphatase Glutathione reductase mutant HGPRT deficiency
PRPP amidotransferase mutant PRPP synthetase mutant Renal underexcretion (
normal ...
9
Sturkie's Avian Physiology
TABLE 3 Patterns of Nitrogen Excretion in Avian Urinea Species Condition Total
N (g/liter) Urate (% of total) NH4 (% of total) Urea (% of total) Domestic fowl Fed
4.4 84.1 6.8 5.2 (Gallus domesticus) Fasted 2.4 57.8 23.0 2.9 Low protein 11 54.7
...
10
Kelley's Textbook of Rheumatology
E0 Tubular epithelial cell Tubular o) a urate load _ O D) E '1' Cl— Lactate m _ 2 o
I I _ {-8 g Nicotinate, U ABCGI DKLJJGI'DOXYIGIGS ll) - ' cu #1 Pyrazlnoate, rate -
rate on etc. /_Ifi ATP (ADP + Pi MRP4 Urate Urate Urate = Urate Urate Urate ...
Gary S. Firestein, Ralph C. Budd, Sherine E. Gabriel, 2012
用語«URATE»を含むニュース項目
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Dacia Logan, in topul celor mai urate masini din istorie
Alaturi de Dacia Logan, in topul celor mai urate masini din istorie au mai fost incluse Hyundai Atos, Fiat Multipla, Ssangyong Rodius, Alfa Romeo Arna, Fiat ... «Ziare.com, 4月 15»
Gout Associated With Reduced Risk for Alzheimer's Disease
Lu et al mention 'antigout medication,' but unfortunately do not say specifically 'urate-lowering medication,' nor do they address any correlation with urate serum ... «Medscape, 3月 15»
Rapid Crystal Dissolution in Gout
Monosodium urate crystals dissolve and are eliminated from joints and soft tissues as serum uric acid levels drop below its saturating point (400 μmol/l). Time to ... «Medscape, 1月 15»
Gout Patients Missed Out on Medication
In a new UK study, patients with gout were found to wait years before being eligible for the recommended urate-lowering treatment. But even after becoming ... «dailyRx, 12月 14»
Long-term Treatment of Gout Is Suboptimal
Only a minority of patients with gout whose disease indications made them candidates for long-term urate-lowering therapy were treated according to current ... «Medscape, 12月 14»
Effects of Green Tea Extract on Serum Uric Acid and Urate …
Objective The objective of this study was to investigate the hypouricemic effects of green tea extract (GTE) in healthy individuals. Methods This study comprised ... «Medscape, 8月 14»
High Urate? Get Moving, Study Finds
High Urate? Get Moving, Study Finds. Regular exercise significantly lessened the excess mortality risk associated with elevated serum uric acid, a large ... «MedPage Today, 7月 14»
Gout, disease of kings, on the rise
It is a type of arthritis where crystals of sodium urate form around the joints. Men are most commonly affected, and other factors that increase a person's risk ... «expressandstar.com, 7月 14»
Prophylaxis for Acute Gout Flares After Initiation of Urate-Lowering …
This review summarizes evidence relating to prophylaxis for gout flares after the initiation of urate-lowering therapy (ULT). We searched MEDLINE via PubMed ... «Medscape, 4月 14»
Treating Parkinson Disease With Urate Elevation?
Medscape recently spoke with Michael A. Schwarzschild, MD, PhD, about the clinical implications of the Safety of Urate Elevation in Parkinson Disease ... «Medscape, 2月 14»
