«ANERGIC» 관련 영어 책
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1
Regulation of Calcium Signaling and Cellular Localization of ...
Surprisingly, we were unable to detect NFAT1 in resting naïve or anergic T cells,
although the same antibody was able to detect NFAT1 in lysates from both
resting and stimulated naïve T cells by Western blots (Figure 4.2 D). This
suggests that ...
Mathangi Srinivasan, 2008
Anergic, self-reactive B cells with this phenotype represent ∼5% of the
peripheral B cell pool in normal mice.485 The IgMlow B cells persist in the spleen
for only 1 to 3 days before being eliminated by the intrinsic, Bcl2-regulated
apoptosis ...
3
The Genetics of Autoimmunity
Surprisingly, degradation of PLCyl and PKCO in anergic T cells was not blocked
by proteasome inhibitors. Moreover, the predominant form of PKC0 we observed
in anergic T cells was a mono-ubiquitinated form (Heissmeyer et al 2004).
Gregory Bock, Jamie Goode, 2005
4
Lymphocyte Development: Cell Selection Events and Signals ...
The. Induction. of. the. Anergic. State. It is unclear whether "incomplete" or "
negative" signaling (involving Signal 1 and CTLA-4) actually induces anergy in
vivo or merely results in the absence of activation. As pointed out earlier, most
studies ...
5
Handbook of B and T Lymphocytes
Furthermore, the early biochemical events associated with TCR occupancy,
including the generation of inositol phosphates (35) and activation of certain
transcription factors (21,39), occur normally in anergic T cell clones. Although IL-
2 ...
6
Immune Tolerance Research Developments
These cells become anergic, a state similar to that with anergic T cells in which
the cell undergoes innate biochemical alterations that prevents it from
undergoing activation following antigen binding, thereby arresting further
differentiation [54].
7
Landmark Papers in Internal Medicine: The First 80 Years of ...
RESULTS RELATED TO PRETREATMENT IMMUNOLOGIC STATUS AND
REPEAT SKIN TESTING Results of skin testing in each patient are shown in
Table 1. Of the 30 patients who had skin tests before treatment, 18 (60%) were
anergic.
Harold C. Sox, Edward J. Huth, 2009
8
The Autoimmune Diseases
These anergic cells migrated from bone marrow to the splenic follicle to join the
mature B-cell pool (Figure 13.2). In the absence of competition from non-self-
reactive B cells, anergic B cells survive in the periphery for several weeks.
However ...
Ian R. Mackay, Noel R Rose, 2006
These mice generated substantial numbers of splenic B-cells that, when
analyzed in a number of functional assays, were 'anergic' (i.e. hyporesponsive);
these animals also manifested an unusual depletion of B-cells from the marginal
zone of ...
Tasuku Honjo, Frederick W. Alt, 1995
10
The Immune Response: Basic and Clinical Principles
The anergic lymphocyte survives but fails to proliferate and differentiate into
effector cells capable of attacking the source of the antigen. Some limited effector
functions may be observed in the primary response, but the anergic lymphocyte ...
Tak W. Mak, Mary E. Saunders, 2005
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Immunotherapy in Hematologic Malignancies
These antibodies have demonstrated that reversing the anergic state of the T cells can result in a clinically meaningful benefit, explains ... «OncLive, 6월 15»
Culling badgers is so meaningless
... test negative (anergic) culprit ( qv. Dave Barton, James Griffiths, Meurig Raymond, Gelli Aur, Adam Henson, and even HRH Princess Anne). «Stroud News and Journal, 6월 15»
Another TB Scare as Woman With Rare Form of TB is Treated at the …
Skin tests are often anergic and they fail to show hidden TB by a falsely negative skin test in some 50% of immune compromised patients. «Newswire, 6월 15»
Deciphering Immune Cell Chatter
Dr. Raulet surmises that the cytokine efficacy was dependent on reversal of the anergic state of the NK cells in the MHC-deficient tumor-bearing ... «Genetic Engineering & Biotechnology News, 4월 15»
Analyses of the TCR repertoire of MHC class II-restricted innate CD4 …
... the activated T cells' MHC class II molecules for regulatory purposes, resulting in the activated T cells becoming either anergic or apoptotic. «Nature.com, 3월 15»
Misdiagnosed cattle behind spread of TB
The ENFER test is routinely used in Ireland to find skin test non-reactor (anergic) active spreader cows. DEFRA have recently started using an ... «Stroud Life, 11월 14»
Cytokine therapy enhances natural killer cell functions against tumor …
When cytokines were absent, the NK cells were anergic, or did not have an immune response, to tumors deficient in MHC class I. Mixed tumors ... «Oncology Nurse Advisor, 11월 14»
Forewarnings of severe disease sought
If a T cell only receives one signal, it becomes unresponsive, or anergic. Abatacept has been approved for infusion for some time, a licence has ... «Irish Medical Times, 7월 14»
Calves condemned to an early death by TB in wake of badger cull …
... for a tb outbreak - including anergic hosts, infected slurry, infected ground-water, iron levels in the soil etc, but only badgers are mentioned. «Western Morning News, 3월 14»
Tb devastates dairy farmer's herd
Husband believes he had anergic cows in his herd because in November 2012, a routine TB test carried out on his farm came back negative. «Stuff.co.nz, 8월 13»
