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1
Immunodeficient animals: models for cancer research
This volume presents the state of the art of research work based on the use of these immunodeficient animal models. One section is dedicated to the biological aspects and immunological properties of immunodeficient mutants.
Wolfgang Arnold, Petra Köpf-Maier, Burkhard Micheel, 1996
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Immunodeficient Rodents: A Guide to Their Immunobiology, ...
This volume is an indispensable reference on the nature of immune defects in rodents and the special techniques necessary to maintain and breed them.
Committee on Immunologically Compromised Rodents, Institute for Laboratory Animal Research, Commission on Life Sciences, 1989
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Immunodeficient Rodents: A Guide to Their Immunobiology, ...
Includes advice on planning for the selection, transportation, housing, and maintenance of these animals. Annotation copyrighted by Book News, Inc., Portland, OR
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Clinical Dilemmas in Primary Liver Cancer
TABLE 26.1 Notable animal trials of targeted gene therapy for HCC Vector
Transgene Model Result Notes Reference Adenovirus IL-12 OR HSV-TK BNL
cells in immunodeficient Combination of vectors significantly [40] model improved
mouse ...
Roger Williams, Simon D. Taylor-Robinson, 2011
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Cancer Stem Cells in Solid Tumors
Table 18.1 also provides a summary of the immunodeficient mouse strains
commonly used for human stem cell transplantation studies, and contrasts the
advantages and disadvantages of each model common to experimental use.
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Melanoma Techniques and Protocols: Molecular, Diagnosis, ...
Experimental Induction of Human Atypical Melanocytic Lesions and Melanoma in
Ultraviolet-Irradiated Human Skin Grafted to Immunodeficient Mice Carola
Berking and Meenhard Herlyn 1. Introduction The development of melanoma and
its ...
Ian M. Clark, Brian J. Nickoloff, Leroy Hood, 2001
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Central Nervous System Diseases and Inflammation
In these experiments chemokine transcripts for CXCL10 and CCL5 were
elevated in CNS tissues isolated from MV infected immunodeficient NSE-CD46/
Rag-2 knock-out (ko) mice, as well as from MV-infected primary hippocampal
neuron ...
Thomas E. Lane, Monica Carson, Conni Bergmann, 2007
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Breast Cancer Research Protocols
In this chapter, we report on how to develop clinically relevant human breast
cancer cell line xenografts in severe combined immunodeficient mice. In severe
combined immunodeficient mice, metastasizing human breast cancer cell lines
were ...
Susan A. Brooks, Adrian Harris, 2006
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Current Topics in Complement II: II
Therefore, to test the role of Ig in triggering CC activation in G-CSF-induced
mobilization of HSPC, immunodeficient RAG2 and SCID mice (lacking both B
and T lymphocytes and Ig) and Jh mice (selectively Ig-deficient) were mobilized
by ...
10
Parasitic Infections in the Compromised Host
Until recently, infections with Crcpto- sporidium spp. were considered rare in
animals, and in humans they were thought to be the result of an opportunistic
pathogen of immunodeficient persons outside its normal host range (4-8). Our
concept ...
Peter D. Walzer, Robert M. Genta, 1988
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Pushing through a tough stretch
They injected human breast cancer cells into the tail of immunodeficient mice and quantified the extracellular ATP released from these cells, ... «Nature.com, 7월 15»
Parasitology: CRISPR for Cryptosporidium
... sporozoites directly back into the intestines of immunodeficient mice, in which the parasites propagated and produced oocysts (Fig. 1). «Nature.com, 7월 15»
Wnt/β-catenin signaling regulated SATB1 promotes colorectal …
... or shSATB1 subcutaneously in six-weeks-old severe combined immunodeficient mice (SCID) and monitored the tumor growth over 4 weeks. «Nature.com, 7월 15»
Multiple myeloma hides in bones like a wolf in sheep's clothing
... cell line and found that it produced significantly less tumor growth in immunodeficient mice than the original human multiple myeloma cells. «Medical Xpress, 7월 15»
Keck School experts study potential treatment for lymphoma in HIV …
... that the USC research is based on in vitro and animal model studies that involved putting human lymphoma cells into immunodeficient mice. «USC News, 7월 15»
Disease modeling and lentiviral gene transfer in patient-specific …
Transplanted immunodeficient model mice lacking α-sarcoglycan showed phenotypical correction and it is proof of principle study for ... «Nature.com, 7월 15»
Cancer researchers ID potential treatment for deadly lymphoma
... that the USC research is based on in vitro and animal model studies that involved putting human lymphoma cells into immunodeficient mice. «Medical Xpress, 7월 15»
[Media Coverage] Young Investigators' Stem Cell Symposium …
They demonstrated that transplanting these in-vitro grown organ buds into an immunodeficient animal led to formation of functional liver tissues ... «Biotechin.Asia, 7월 15»
Damon Runyon Cancer Research Foundation
Kaposi sarcoma (KS), a potentially fatal cancer especially in immunodeficient individuals, is caused by human herpes virus-8 (HHV-8), ... «EurekAlert, 6월 15»
Heat-shock factor 2 is a suppressor of prostate cancer invasion
Progression of metastatic human prostate cancer to androgen independence in immunodeficient SCID mice. Nat Med 1997; 3: 402–408. «Nature.com, 6월 15»
