इंग्रजी मध्ये ISOFORM म्हणजे काय?
प्रथिने आयसोफॉर्म
प्रोटीन आयसोफॉर्म हे त्याच प्रोटीनच्या विविध प्रकारांपैकी एक आहे. अतिशय प्रथिने असलेल्या जीनच्या डुप्लिकेटपासून वेगळ्या प्रकारच्या प्रथिनांचे वेगवेगळे प्रकार बनवता येऊ शकतात- 'एक समान प्रथिने' किंवा 'प्रथिन' ही अलीकडील वर्षांतील कोट्यावधी वर्षांपूर्वी डुप्लीकेट केलेल्या आणि नंतर मोठ्या प्रमाणात फरक असलेल्या एका पूर्वजांच्या वंशावळीतून उद्भवणारे अत्यंत भिन्न पाललन रचना, कार्यक्षमता किंवा पर्यायी splicing द्वारे समान जीनपासून निर्माण होऊ शकते. जुन्या शाखेत एकास त्याच जीनच्या alleles वर्णन करण्यासाठी isoform टर्म वापर उद्भवू शकते, पण सध्या अटी paralogous आणि वैकल्पिकरित्या spliced प्रोटीन करण्यासाठी मुख्यतः संदर्भ, alleles नाही. समस्थानिकांच्या शोधाने प्रथिने कोडिंग क्षेत्रांमध्ये छोट्या प्रमाणामध्ये मानवी जीनोम प्रकल्पाचा खुलासा केला आहे: त्याच जनुकांद्वारे एन्कोड केलेली विविध प्रथिने प्रोटिओची विविधता वाढवू शकतात. डीएनएच्या पातळीवर आयसोफ्रॉड्स सहजपणे सीडीएनए ट्रान्स्क्रिप्ट अभ्यासाने ओळखतात.
इंग्रजी शब्दकोशातील isoform व्याख्या
शब्दकोशमध्ये isoform ची व्याख्या ही प्रथिने अनेक प्रकारचे आहे, जी एकतर त्याच जनुक किंवा विविध जनुकांपासून बनलेली आहे, त्यातील प्रत्येक प्रक्रिया इतरांप्रमाणेच असते.
«ISOFORM» संबंधित इंग्रजी पुस्तके
खालील ग्रंथसूची निवडीमध्ये
isoform चा वापर शोधा. इंग्रजी साहित्यामध्ये वापराचा संदर्भ देण्यासाठी
isoform शी संबंधित पुस्तके आणि त्याचे थोडक्यात उतारे.
1
Identification and Characterization of a Conserved
Isoform ...
The Dorsal-related immunity factor, Dif is a Drosophilid specific transcription factor that likely arose via gene duplication of Dorsal.
2
Regulation of Myosin II
Isoform Localization and Activation ...
Insulin stimulated glucose uptake is a critical component of glucose homeostasis.
Franklin Kent Fulcher,
2006
3
Function and Regulation of NA+/H+ Exchanger
Isoform 1 in ...
In conclusion, NHEI1 activity contributes to Na+ and Ca 2+ homeostasis disturbance following ischemia.
4
Characterization of Human Pyruvate Dehydrogenase Kinase ...
The Q144 mutation in the R domain caused 14-fold weaker K+ binding with ATP in the Cat domain but did not alter the weaker K+ binding with ADP unless Pi was included.
5
Structures of PKA RII Beta Holoenzymes Define
Isoform Diversity
Comparison of the cAMP bound and C-subunit bound conformations of the R-
subunits reveal both the dramatic conformational changes of the R- subunit upon
C-subunit binding, and the isoform specific differences between the cAMP bound
...
Simon Hugh Jolyon Brown,
2008
6
Isoform-specific Roles of Akt1 and Akt2 in Cardiac Growth ...
Akt isoform expression in WT and aktf- mice. Left, AMCMs from WT and aktl"'"
mice were subjected to Akt1 , Akt2, PI-3 kinase(p1 10a), and ILK-specific
immunoblotting. Right, mean immunoreactive band densitometry of scanned
immunoblots ...
Brian Jesse DeBosch,
2008
7
Effects of genetic variation and aging on splice-
isoform ...
Subsequently, splice-isoform ratios were assayed in both hearts and kidneys for a small number of samples. Splicing is also tightly controlled in the heart. Four of the five ratios differed significantly between the two tissues.
Jennifer L. Chisa, University of Michigan,
2006
8
International Review of Neurobiology
TABLE II (Continued) Group Protein ID p Description IPI00332838 Splice isoform
5 of basic fibroblast growth factor receptor 1 precursor 214 IPI00220631 0.95
Splice isoform 2 of ADAM 22 precursor IPI00220632 Splice isoform 3 of ADAM
22 ...
Ronald J. Bradley, R. Adron Harris, Peter Jenner,
2006
9
The Sodium Pump: Structure, Mechanism, and Regulation : ...
both T3 and DEX caused an increase in a2 isoform transcript levels similar to that
observed with T3 alone. However, the T3 stimulation of a3 isoform mRNA was
not observed, suggesting that DEX specifically represses the induction of a3 ...
Society of General Physiologists. Symposium, Jack H. Kaplan, Paul De Weer,
1991
10
Diagnostic and Therapeutic Advances in Hematologic Malignancies
The L-type PML-RARa isoform is expressed in approximately 55% of adult
patients with APL. while the S and V isoforms are expressed in approximately 35
% and 8% of patients, respectively [65]. In the pediatric population, the V isoform
...
Martin S. Tallman, Leo I. Gordon,
1998
नवीन गोष्टी ज्यामध्ये «ISOFORM» ही संज्ञा समाविष्ट आहे
खालील बातम्यातील आयटमच्या संदर्भात राष्ट्रीय आणि आंतरराष्ट्रीय पत्रकार कशाबद्दल बोलले आहेत आणि
isoform ही संज्ञा कशी वापरली आहे ते शोधा.
Scientists Identify New Antibody Which Could Aid in Treatment of …
Basically, the research team found that a misshapen isoform of the tau protein could develop in just 12 hours after the onset of TBI which can ... «Pioneer News, जुलै 15»
Blood Cancer Journal - Targeting the Pim kinases in multiple myeloma
The longer 44kDa isoform of Pim-1 is derived from use of an upstream CUG start codon at nucleotides 158–160 and localizes to the plasma ... «Nature.com, जुलै 15»
BMC Genomics | Full text | Analysis of the TGFβ-induced program in …
Among these, TP63 attenuates EMT in prostate cells [43] and alternatively spliced isoform ΔNp63α inhibits EMT in human bladder cancer cells ... «BMC Blogs Network, जुलै 15»
BCR-signaling-induced cell death demonstrates dependency on …
Indeed, BCR stimulation-driven Bim upregulation has been attributed to a combination of transcriptional upregulation and isoform skewing, via ... «Nature.com, जुलै 15»
New research offers potential for early intervention to prevent …
In a study published today in the online edition of the journal Nature, the researchers found that a misshapen isoform of the tau protein can ... «News-Medical.net, जुलै 15»
Molecular genetics and pathogenesis of cardiomyopathy
Loss of desmoplakin isoform I causes early onset cardiomyopathy and heart failure in a Naxos-like syndrome. J. Med. Genet. 43, e5 (2006). «Nature.com, जुलै 15»
Novel and recurrent CIB2 variants, associated with nonsyndromic …
CIB2 c.196C>T affects all known CIB2 protein isoforms except isoform CIB2-006 as indicated in ENSEMBL (GRCh38) and in the Genome ... «Nature.com, जुलै 15»
Epigenetics: Disrupting histone lysine methylation
Grebien et al. suggest that this strategy may extend to cases of AML that are driven by the oncogenic p30 isoform of the transcription factor ... «Nature.com, जुलै 15»
Insider Selling: TG Therapeutics Director Sells $290360.00 in Stock …
TGR-1202 is an orally available PI3K delta inhibitor with nanomolar potency to the delta isoform and several fold selectivity over the alpha, beta ... «WKRB News, जुलै 15»
TG Therapeutics Director Sells $290360.00 in Stock (TGTX)
TGR-1202 is an orally available PI3K delta inhibitor with nanomolar potency to the delta isoform and several fold selectivity over the alpha, beta ... «sleekmoney, जुलै 15»