Maksud "microsomal" dalam kamus Corsica

SEBUTAN MICROSOMAL DALAM CORSICA

microsomal  [ˌmaɪkrəˈsəʊməl]

APAKAH MAKSUD MICROSOMAL dalam CORSICA?

Microsome

Microsome

Dalam biologi sel, mikrosom adalah artifak seperti vesikel yang dibentuk semula daripada kepingan reticulum endoplasma apabila sel eukariotik dipecahkan di makmal; secara takrif, mikrosom tidak selalunya hadir dalam sel hidup. Mikrosom boleh tertumpu dan dipisahkan dari serpihan selular lain dengan sentrifugasi berbeza. Unsur sel, nukleus, dan mitokondria yang tidak pecah pada 10,000g, manakala enzim larut dan ER yang berpecah, yang mengandungi cytochrome P450, kekal dalam penyelesaian. Pada 100,000g, yang dicapai dengan putaran centrifuge yang lebih cepat, sedimen ER daripada larutan sebagai pelet tetapi enzim larut kekal dalam supernatan. Dengan cara ini, cytochrome P450 dalam mikrosom adalah tertumpu dan terpencil. Mikrosom mempunyai warna coklat kemerah-merahan, disebabkan kehadiran faktor koin yang mengandungi besi, heme, dalam P450s. P450s sangat banyak di dalam tikus, tikus dan manusia. Mikrosom adalah alat yang berharga untuk menyiasat metabolisme sebatian dan untuk mengkaji interaksi ubat dadah dengan in vitro-research. Penyelidik sering memilih banyak mikrosom berdasarkan tahap aktiviti enzim CYP spesifik.

In cell biology, microsomes are vesicle-like artifacts re-formed from pieces of the endoplasmic reticulum when eukaryotic cells are broken-up in the laboratory; by definition, microsomes are not ordinarily present in living cells. Microsomes can be concentrated and separated from other cellular debris by differential centrifugation. Unbroken cells, nuclei, and mitochondria sediment out at 10,000g, whereas soluble enzymes and fragmented ER, which contains cytochrome P450, remain in solution. At 100,000g, achieved by faster centrifuge rotation, ER sediments out of solution as a pellet but the soluble enzymes remain in the supernatant. In this way, cytochrome P450 in microsomes is concentrated and isolated. Microsomes have a reddish brown color, due to the presence of the iron-containing co-factor, heme, in the P450s. P450s are highly abundant in livers of rats, mice and humans. Microsomes are a valuable tool for investigating the metabolism of compounds and for examining drug-drug interactions by in vitro-research. Researchers often select microsome lots based on the enzyme activity level of specific CYPs.

Definisi microsomal dalam kamus Corsica

Takrif mikrosom dalam kamus adalah atau berkaitan dengan mana-mana zarah kecil yang terdiri daripada ribosomes dan serpihan retikulum endoplasma yang dipasang yang boleh diasingkan dari sel oleh tindakan sentrifugal.

TERJEMAHAN MICROSOMAL

Cari terjemahan microsomal kepada 25 bahasa dengan penterjemah Corsica pelbagai bahasa kami.

Terjemahan microsomal dari Corsica ke bahasa lain yang dibentangkan dalam bahagian ini telah diperolehi menerusi terjemahan statistik automatik; di mana unit terjemahan penting adalah perkataan «microsomal» dalam Corsica.

• Penterjemah Corsica - Cina: 微粒
• Penterjemah Corsica - Czech: microsomal
• Corsica: microsomal
• Penterjemah Corsica - Hindi: माइक्रोसोमल
• Penterjemah Corsica - Amhara: الميكروسومي
• Penterjemah Corsica - Rusia: микросомальный
• Penterjemah Corsica - Punjabi: microssomal
• Penterjemah Corsica - Basque: মাইক্রোসোমাল
• Penterjemah Corsica - Frisia: microsomes
• Penterjemah Corsica - Melayu: Microsomal
• Penterjemah Corsica - Chichewa: mikrosomalen
• Penterjemah Corsica - Jepun: ミクロソーム
• Penterjemah Corsica - Kreol Haiti: 미세 소체
• Penterjemah Corsica - Jerman: Microsomal
• Penterjemah Corsica - Vietnam: microsome
• Penterjemah Corsica - Tagalog: மைக்ரோசோமல்
• Penterjemah Corsica - Marathi: मायक्रोसोमल
• Penterjemah Corsica - Turki: mikrozomal
• Penterjemah Corsica - Itali: microsomiale
• Penterjemah Corsica - Poland: mikrosomalnych
• Penterjemah Corsica - Ukraine: мікросомальний
• Penterjemah Corsica - Romania: microzomale
• Penterjemah Corsica - Cina: μικροσωμικά
• Penterjemah Corsica - Afrikaans: mikrosomale
• Penterjemah Corsica - Swahili: mikrosomalt
• Penterjemah Corsica - Parsi: mikrosomal

CORSICA BUKU YANG BERKAIT DENGAN «MICROSOMAL»

Ketahui penggunaan microsomal dalam pilihan bibliografi berikut. Buku yang berkait dengan microsomal dan ekstrak ringkas dari yang sama untuk menyediakan konteks penggunaannya dalam kesusasteraan Corsica.

Endocrine Autoimmunity and Associated Conditions

Thyroid antibodies Amino et al. [2] first documented the association of postpartum thyroiditis with high titres of thyroid antibodies, and the dramatic rise of microsomal (TPO) antibody titre after delivery was clearly shown in the study of Fung et al ...

Anthony P. Weetman, 1998

Pesticide Residues in Food - 2004: Evaluations 2004, ...

The liver samples were separated into microsomal and cytosolic fractions and the following biochemical parameters were investigated: protein content of microsomal and cytosolic fractions; microsomal cytochrome P450; microsomal ...

World Health Organization, 2006

Clinically Oriented Pharmacology

Microsomal enzymes are located on smooth endoplasmic reticulum in the cells of liver, lungs, kidneys are located on ... NonNonNonNon----microsomal enzym microsomal enzym microsomal enzym microsomal enzymes:es:es:es: They are ...

Dr J G Buch

Conjugation-Dependent Carcinogenicity and Toxicity of ...

McLellan, L. 1., Wolf, C. R., and Hayes, J. D. (1989). Human microsomal glutathione Stransferase, Its involvement in the conjugation of hexachloro-1.3- butadiene with glutathione. Biochem. J. 258, 87-93. Morgenstem, R., and DePierre, J. W. ...

‎1994

The Enzymes

Schlossman and Bell critically addressed the question of whether the microsomal glycerol-P acyltransferase activity and the dihydroxyacetoneP acyltransferase activity were dual catalytic functions of a single microsomal enzyme (13).

Paul D. Boyer, 1983

Hormonal Steroids: Proceedings of the Fifth International ...

Fig. 6. Ouehterlony immunodiffusion plate with antibodies in centre'well. In outer wells are: 1 and 4. microsomal extract: 2 and 5. cytosol; 3 and 6. purified E2 binder [If]. Table 4. Oestradiol receptor concentration in the pancreas in comparison.

V. H. T. James, J. R. Pasqualini, 1979

Postharvest Biology and Technology of Fruits, Vegetables, ...

The microsomal PLD also showed dual optimal values of activation at pH values of 5 and 7, respectively. Similar pH activation profiles have been observed in tomato microsomal membrane (K. Tiwari, unpublished). 9.3.2.2 Kinetic analysis of ...

Gopinadhan Paliyath, Ph.D., Dennis P. Murr, Avtar K. Handa, 2009

Phytochemical Biopesticides

In most instances, induction of various microsomal monooxygenase activities by allelochemicals was higher than that of cytochrome P450 content (Yu 1982, 1983 , 1985; Yu and Ing 1984; Moldenke et al. 1983; Snyder et al. 1993) and there ...

Opender Koul, G. S. Dhaliwal, 2003

Toxicology of Glutathione Transferases

Liver Dis., 35 Suppl. 2, S49-S60, 2003. 101. Lundqvist, G. and Morgenstern, R., Mechanism of activation of rat liver microsomal glutathione transferase by noradrenaline and xanthine oxidase, Biochem. Pharmacol, 43 (8), 1725-1728, 1992.

Yogesh C. Awasthi, 2006

Autoantibodies

... Liver Cytosol Antigen Type 1 Autoantibodies (LC-1), Liver Kidney Microsomal Autoantibodies (LKM), and Liver Microsomal Autoantibodies (LM) 477 Liver Kidney Microsomal/Liver Microsomal Autoantibodies, ...

Yehuda Shoenfeld, Pier Luigi Meroni, M. Eric Gershwin, 2013

BARANGAN BERITA YANG TERMASUK TERMA «MICROSOMAL»

Ketahui apa yang diterbitkan oleh akhbar nasional dan antarabangsa dan cara istilah microsomal digunakan dalam konteks perkara berita berikut.

KLF5 promotes breast cancer proliferation, migration and invasion in …

Kruppel-like factor 5 transcription factor promotes microsomal prostaglandin E2 synthase 1 gene transcription in breast cancer. J Biol Chem ... «Nature.com, Jul 15»

Welcome to to the Irish Medical Times website

Drug interactions: Microsomal enzyme-inducing drugs, use a barrier method during and for 28 days after admin. Medicinal charcoal. Adverse ... «Irish Medical Times, Jul 15»

The maize cytochrome P450 CYP79A61 produces …

The resulting microsomal protein fraction was homogenized in 2 mL TEG buffer (50 mM Tris–HCl, 1 mM EDTA, 30 % w/v glycerol) using a glass ... «BMC Blogs Network, Mei 15»

Aegerion Pharmaceuticals Achieves Primary Endpoint in Phase III …

Lomitapide, marketed as JUXTAPID® in the U.S., is a microsomal triglyceride transfer protein (MTP) inhibitor that works independently of LDL ... «GlobeNewswire, Mei 15»

Temporal gene expression profiling of the rat knee joint capsule …

P4HB is a microsomal triglyceride transfer protein involved in intracellular lipid exchange [16] and levels of the corresponding transcript and ... «BMC Blogs Network, Mei 15»

Aminomethyl spectinomycins as therapeutics for drug-resistant …

Compounds also demonstrated no mammalian cytotoxicity, improved microsomal stability, and favorable pharmacokinetic properties in rats. The lead compound ... «Science Magazine, Mei 15»

A Comprehensive Update On DURECT Corp. (DRRX)

It also inhibits lipid absorption and transportation by blocking microsomal triglyceride transfer protein (MTP) similar to Aegerion's Juxtapid ... «Seeking Alpha, Mei 15»

AOP Orphan Launches Lojuxta® (lomitapide) for Treatment of …

Lojuxta's mechanism of action is independent of the LDL receptors and is based on inhibiting the microsomal triglyceride transfer protein that is ... «b3c newswire, Apr 15»

AOP Orphan Launches Lojuxta to the Austrian Market

Lojuxta's mechanism of action is independent of the LDL receptors and is based on inhibiting the microsomal triglyceride transfer protein that is ... «Drug Discovery & Development, Apr 15»

Aegerion Pharmaceuticals Expects Little Growth In 2015 (AEGR)

Aegerion's core product is Juxtapid (sold as Lojuxta in Europe), a microsomal triglyceride transfer protein (MTP) inhibitor indicated as an ... «Seeking Alpha, Mac 15»