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Maksud "paclitaxel" dalam kamus Corsica

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section

SEBUTAN PACLITAXEL DALAM CORSICA

paclitaxel  [ˌpæklɪˈtæksəl] play
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KATEGORI TATABAHASA PACLITAXEL

kata nama
adjektif
kata kerja
kata sifat kerja
kata ganti nama
kata depan
konjungsi
penentu
seru

APAKAH MAKSUD PACLITAXEL dalam CORSICA?

Klik untuk melihat definisi asal «paclitaxel» dalam kamus Corsica.
Klik untuk melihat terjemahan automatik definisi dalam Melayu.
paclitaxel

Paclitaxel

Paclitaxel

Paclitaxel adalah perencat mitosis yang digunakan dalam kemoterapi kanser; ia dan docetaxel mewakili keluarga dadah taxan. Paclitaxel ditemui pada tahun 1967 sebagai hasil daripada program pemeriksaan yang dibiayai Institut Kanser Kebangsaan A.S.; Monroe Wall dan Mansukh Wani mengasingkan dadah dari kulit yew Pasifik, Taxus brevifolia, dan menamakannya "taxol". Dibangunkan secara komersil oleh Bristol-Myers Squibb, nama generik telah berubah menjadi "paclitaxel" dengan BMS menjual kompaun di bawah tanda dagangan sebagai Taxol. Taxol ™ diformulasikan dengan minyak kastor dan etanol polietoksilat; paclitaxel juga boleh didapati sebagai penggantungan suntikan ubat terikat albumin, di mana ia dijual di bawah tanda dagangan Abraxane®. Pakar klinik kadangkala menggunakan singkatan "PTX" untuk paclitaxel, yang digalakkan kerana ia bukan pengecam unik. Mekanisme tindakan Paclitaxel melibatkan penstabilkan mikrotubul selular; akibatnya, ia mengganggu pecahan normal microtubules semasa pembahagian sel. Paclitaxel digunakan untuk merawat pesakit dengan paru-paru, ovari, payudara, dan kanser kepala dan leher, dan bentuk lanjut sarcoma Kaposi. Paclitaxel is a mitotic inhibitor used in cancer chemotherapy; it and docetaxel represent the taxane family of drugs. Paclitaxel was discovered in 1967 as a result of a U.S. National Cancer Institute-funded screening program; Monroe Wall and Mansukh Wani isolated the drug from the bark of the Pacific yew, Taxus brevifolia, and named it "taxol". Developed commercially by Bristol-Myers Squibb, the generic name has changed to "paclitaxel" with BMS selling the compound under trademark as Taxol. Taxol™ is formulated with a polyethoxylated castor oil and ethanol; paclitaxel is also available as a injectable suspension of albumin-bound drug, where it is sold under the trademark Abraxane®. Clinicians sometimes use the abbreviation "PTX" for paclitaxel, which is discouraged because it is not a unique identifier. Paclitaxel's mechanism of action involves its stabilization of cellular microtubules; as a result, it interferes with the normal breakdown of microtubules during cell division. Paclitaxel is used to treat patients with lung, ovarian, breast, and head and neck cancers, and advanced forms of Kaposi's sarcoma.

Definisi paclitaxel dalam kamus Corsica

Takrif paclitaxel dalam kamus adalah ubat yang berasal dari pokok yew dan digunakan untuk merawat kanser.

The definition of paclitaxel in the dictionary is a drug derived from the yew tree and used to treat cancer.

Klik untuk melihat definisi asal «paclitaxel» dalam kamus Corsica.
Klik untuk melihat terjemahan automatik definisi dalam Melayu.

CORSICA PERKATAAN YANG BERIMA DENGAN PACLITAXEL


adnexal
ædˈnɛksəl
antefixal
ˌæntɪˈfɪksəl
axal
ˈæksəl
axel
ˈæksəl
axle
ˈæksəl
cacomixl
ˈkækəˌmɪksəl
cacomixle
ˈkækəˌmɪksəl
coaxal
kəʊˈæksəl
coxal
ˈkɒksəl
fo´c´s´le
ˈfəʊksəl
forecastle
ˈfəʊksəl
megapixel
ˈmɛɡəˌpɪksəl
paradoxal
ˌpærəˈdɒksəl
pixel
ˈpɪksəl
pyridoxal
ˌpɪrɪˈdɒksəl
Texel
ˈtɛksəl
transaxle
trænzˈæksəl
voxel
ˈvɒksəl
Weichsel
ˈvaiksəl
wraxle
ˈræksəl

CORSICA PERKATAAN YANG BERMULA SEPERTI PACLITAXEL

packframe
packhorse
packing
packing box
packing case
packing density
packing fraction
packing house
packman
packsack
packsaddle
packthread
packwax
packway
paco
pact
paction
pactional
pactum
pacy

CORSICA PERKATAAN YANG BERAKHIR SEPERTI PACLITAXEL

angel
apparel
at the wheel
bel
cancel
Castrop-Rauxel
channel
Daniel
del
diesel
el
excel
feel
fuel
Gabriel
gel
Handel
hostel
hotel
Kastrop-Rauxel

Sinonim dan antonim paclitaxel dalam kamus sinonim Corsica

SINONIM

Terjemahan «paclitaxel» ke dalam 25 bahasa

PENTERJEMAH
online translator

TERJEMAHAN PACLITAXEL

Cari terjemahan paclitaxel kepada 25 bahasa dengan penterjemah Corsica pelbagai bahasa kami.
Terjemahan paclitaxel dari Corsica ke bahasa lain yang dibentangkan dalam bahagian ini telah diperolehi menerusi terjemahan statistik automatik; di mana unit terjemahan penting adalah perkataan «paclitaxel» dalam Corsica.

Penterjemah Corsica - Cina

紫杉醇
1,325 juta pentutur

Penterjemah Corsica - Czech

paclitaxel
570 juta pentutur

Corsica

paclitaxel
510 juta pentutur

Penterjemah Corsica - Hindi

Paclitaxel
380 juta pentutur
ar

Penterjemah Corsica - Amhara

باكليتاكسيل
280 juta pentutur

Penterjemah Corsica - Rusia

паклитаксел
278 juta pentutur

Penterjemah Corsica - Punjabi

paclitaxel
270 juta pentutur

Penterjemah Corsica - Basque

paclitaxel
260 juta pentutur

Penterjemah Corsica - Frisia

paclitaxel
220 juta pentutur

Penterjemah Corsica - Melayu

Paclitaxel
190 juta pentutur

Penterjemah Corsica - Chichewa

Paclitaxel
180 juta pentutur

Penterjemah Corsica - Jepun

パクリタキセル
130 juta pentutur

Penterjemah Corsica - Kreol Haiti

파클리탁셀
85 juta pentutur

Penterjemah Corsica - Jerman

Paclitaxel
85 juta pentutur
vi

Penterjemah Corsica - Vietnam

paclitaxel
80 juta pentutur

Penterjemah Corsica - Tagalog

பாக்லிடேக்சலின்
75 juta pentutur

Penterjemah Corsica - Marathi

पॅक्लिटाक्सेल
75 juta pentutur

Penterjemah Corsica - Turki

paklitaksel
70 juta pentutur

Penterjemah Corsica - Itali

paclitaxel
65 juta pentutur

Penterjemah Corsica - Poland

paklitaksel
50 juta pentutur

Penterjemah Corsica - Ukraine

паклитаксел
40 juta pentutur

Penterjemah Corsica - Romania

paclitaxel
30 juta pentutur
el

Penterjemah Corsica - Cina

πακλιταξέλη
15 juta pentutur
af

Penterjemah Corsica - Afrikaans

paclitaxel
14 juta pentutur
sv

Penterjemah Corsica - Swahili

paklitaxel
10 juta pentutur
no

Penterjemah Corsica - Parsi

paclitaxel
5 juta pentutur

Aliran kegunaan paclitaxel

ALIRAN

KECENDERUNGAN PENGGUNAAN TERMA «PACLITAXEL»

0
100%
KEKERAPAN
Agak luas digunakan
75
/100
Peta yang ditunjukkan di atas memberikan kekerapan penggunaan terma «paclitaxel» dalam negara berbeza.
Kecenderungan carian utama dan penggunaan umum paclitaxel
Senarai carian utama yang dibuat oleh pengguna untuk mengakses kamus Corsica dalam talian kami dan ungkapan yang paling banyak digunakan dengan perkataan «paclitaxel».

KECENDERUNGAN PENGGUNAAN TERMA «PACLITAXEL» DARI MASA KE MASA

Grafik menyatakan evolusi tahunan kekerapan penggunaan perkataan «paclitaxel» selama 500 tahun yang lalu. Pelaksanaannya adlah berdasarkan kepada menganalisa kekerapan istilah «paclitaxel» muncul dalam sumber bercetak digital dalam Corsica antara tahun 1500 dan hari ini.

Contoh penggunaan dalam kesusasteraan Corsica, petikan dan berita mengenai paclitaxel

CONTOH

CORSICA BUKU YANG BERKAIT DENGAN «PACLITAXEL»

Ketahui penggunaan paclitaxel dalam pilihan bibliografi berikut. Buku yang berkait dengan paclitaxel dan ekstrak ringkas dari yang sama untuk menyediakan konteks penggunaannya dalam kesusasteraan Corsica.
1
Glioblastoma:: Molecular Mechanisms of Pathogenesis and ...
The sensitivity of four human (U87MG, U373MG, H80, and D324) and two rat (9L and F98) brain tumor cell lines to paclitaxel was evaluated (Cahan et al. 1994). Paclitaxel in a time-dependent way showed more sensitivity to human cell lines ...
Swapan K. Ray, 2009
2
The Chemistry and Pharmacology of Taxol® and its Derivatives
total urinary excretion of paclitaxel. In plasma, the maximal concentrations were observed at the end of the infusion period, reaching 2.3-6.0 ttM for paclitaxel and 0.11 uM for 7-epi-paclitaxel. Thus, the plasma concentration of 7-epi-paclitaxel ...
H. Timmerman, V. Farina, 1995
3
Current Pharmaceutical Design
analyzed [46]. IC50 (50% inhibitory concentrations) values of these two taxoids are in the nanomolar range. Docetaxel generally is two to four fold more cytotoxic than paclitaxel. The sensitivity profile of the cell lines, which is based on the IC50  ...
4
Macromolecular Anticancer Therapeutics
Of various paclitaxel prodrugs including that of polymeric and other types of modified forms, the lipid conjugates of paclitaxel received greater attention due to the better ability of lipid macromolecules to penetrate the cell membranes and also ...
L. Harivardhan Reddy, Patrick Couvreur, 2010
5
The Combination of Nab-paclitaxel and Bevacizumab Therapy ...
Unlike other mitotic inhibitors, paclitaxel has a specific binding site on the microtubules and it promotes the microtubules polymerization without additional 125 cofactors 124. Paclitaxel is very hydrophobic and its administration requires the use ...
Lisa Danielle Volk, 2008
6
Cancer Chemotherapy and Biotherapy: Principles and Practice
accumulation of paclitaxel molecules in tumor and normal tissue via SPARC. 389,390 In another report of a randomized cross-over pharmacokinetic study of PBPPI (260 mg/m2 over 30 minutes) and paclitaxel formulated in polyoxyethylated ...
Bruce A. Chabner, Dan L. Longo, 2011
7
Medicinal Chemistry of Bioactive Natural Products
3.5 DESIGN, SYNTHESIS, AND PHARMACOLOGICAL ACTIVITY OF PRODRUGS OF PACLITAXEL Currently the paclitaxel formulation contains a surfactant, Cremophor EL, to improve the poor water solubility of the drug. Some adverse ...
Xiao-Tian Liang, Wei-Shuo Fang, 2006
8
Investigation of the Effects of Alpha-TEA, ...
By far the most environmentally sensitive process is the one that the majority of paclitaxel production today uses. Plant cell fermentation (PCF) technology, involves using calluses of a specific taxus cell line that are then propagated in aqueous ...
Paul Brian Latimer, 2008
9
Cancer Management in Man: Chemotherapy, Biological Therapy, ...
AbraxaneTM (nanoparticle albumin-bound paclitaxel, nab-paclitaxel), the most recently approved form of the taxane compounds, is an albumin-coated formulation of paclitaxel. In order to eliminate the need for the solvents required to increase ...
Boris R. Minev, 2011
10
Biomanufacturing
Paclitaxel and related taxanes have received considerable attention because of their potential antitumor activity against a variety of tumors, e.g. breast cancer, ovarian cancer, AIDS-related Kaposi's sarcoma, and non-small cell lung cancer [ 2].
Jian-Jiang Zhong, 2004

BARANGAN BERITA YANG TERMASUK TERMA «PACLITAXEL»

Ketahui apa yang diterbitkan oleh akhbar nasional dan antarabangsa dan cara istilah paclitaxel digunakan dalam konteks perkara berita berikut.
1
CTI BioPharma Corp EVP Jack W. Singer Sells 15000 Shares (CTIC)
... a biologically-enhanced chemotherapeutic agent that links paclitaxel to a biodegradable polyglutamate polymer, resulting in a new chemical ... «The Legacy, Jul 15»
2
Adding Onartuzumab to Triple-Negative Breast Cancer Treatment …
The addition of onartuzumab to paclitaxel with or without bevacizumab did not provide clinical benefit to patients with predominantly ... «Cancer Therapy Advisor, Jul 15»
3
Mayo Clinic researchers study HDAC inhibitors to find effective …
In testing multiple HDAC inhibitors in combination with the chemotherapy drug paclitaxel, known to give some benefit for this aggressive cancer ... «News-Medical.net, Jul 15»
4
Researchers decode molecular action of combination therapy for …
In testing multiple HDAC inhibitors in combination with the chemotherapy drug paclitaxel, known to give some benefit for this aggressive cancer ... «Medical Xpress, Jul 15»
5
Neratinib in HER2-Positive Breast Cancer
The phase II NEfERTT trial evaluated neratinib and paclitaxel versus trastuzumab and paclitaxel as first-line treatment in individuals with ... «OncLive, Jul 15»
6
Failure to Follow Weight-Based Chemo Guidelines Lowers Survival …
Compared with women of normal weight, obese women received less paclitaxel and carboplatin per kilogram of body weight and lower dose ... «OncLive, Jul 15»
7
Researcher invents chemo delivery system that minimizes impact on …
More information: "Novel ZnO hollow-nanocarriers containing paclitaxel targeting folate-receptors in a malignant pH-microenvironment for ... «Medical Xpress, Jul 15»
8
Cerulean Commences Dosing in CRLX101-Weekly Paclitaxel
Paclitaxel, a widely used chemotherapy used as subsequent therapy for the treatment of advanced ovarian cancer, has anti-angiogenic ... «AZoNano.com, Jul 15»
9
Cerulean doses first patient in Phase Ib trial of CRLX101-paclitaxel
Paclitaxel has anti-angiogenic properties which can induce hypoxic conditions, leading to the up-regulation of hypoxia inducible factor 1a, ... «Pharmaceutical Business Review, Jul 15»
10
Holston Valley Physician Co-authors Article in New England Journal …
This study was called the Lutonix Paclitaxel-Coated Balloon for the Prevention of Femoropopliteal Restenosis 2 trial. The authors concluded ... «Kingsport Times News, Jul 15»

RUJUKAN
« EDUCALINGO. Paclitaxel [dalam talian]. <https://educalingo.com/ms/dic-en/paclitaxel> Tersedia. Mei 2024 ».
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