CO OZNACZA SŁOWO DEGRANULATION
Degranulacja
Degranulacja jest procesem komórkowym, który uwalnia cząsteczki cytotoksyczne przeciwbakteryjne z pęcherzyków wydzielniczych zwanych granulkami znajdującymi się wewnątrz niektórych komórek. Jest używany przez kilka różnych komórek zaangażowanych w układ odpornościowy, w tym granulocyty i komórki tuczne. Jest również używany przez niektóre limfocyty takie jak naturalne komórki zabójców i cytotoksyczne limfocyty T, których głównym celem jest zniszczenie inwazji drobnoustrojów.
Definicja słowa degranulation w słowniku
Definicja degranulacji w słowniku jest procesem komórkowym, w którym ziarniaki cytoplazmatyczne w obrębie pewnych komórek wydzielają swoją zawartość, często na zewnątrz komórki.
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1
Basophil and Mast Cell
Degranulation and Recovery: Basophil ...
Basophil and Mast Cell Degranulation and Recovery Ann M. Dvorak. 1985;
Triggiani et al., 1985); the demonstration of increased heart rate and ST segment
depression in normal volunteers receiving infusions of histamine (Triggiani et al.,
...
2
Weight Loss, Exercise and Health Research
Intense. Exercise. Stimulates. Blood. Neutrophil. Degranulation. in. Humans. and.
Rats. Vladimir I. Morozov' and Michael I. Kalinski Department of Biochemistry,
Research Institute of Physical Culture, Dynamo Ave. 2, St. Petersburg 1971 10, ...
3
The Mast Cell in Health and Disease
MARTHA V. WHITE National Institute of Allergy and Infectious Diseases National
Institutes of Health Bethesda, Maryland I. Introduction Degranulation of human
mast cells and basophils can be induced by a variety of immunological and ...
4
Life's Matrix: A Biography of Water
These antibodies become attached to sites at the surface of the basophil cells,
and it is the interaction of the anchored IgE molecules with the allergens that
promotes degranulation. Benveniste's group was studying this allergenic
response ...
5
Mast Cells in Allergic Diseases
Furthermore, our studies in human mast cells demonstrated that the concurrent
addition of siRNAs targeted towards NTAL and LAT was more effective at
blocking degranulation than when added separately [Tkaczyk and Gilfillan,
unpubl.
Hirohisa Saito, Yoshimichi Okayama,
2005
6
Therapeutic Targets in Airway Inflammation
Evidence for Mast Cell Degranulation in ADA-Deficient Lungs Mast cells release
mediators that influence lung inflammation (50). ADA-deficient mice show
extensive lungmastcell degranulationinassociation withelevatedadeno- sine
levels ...
N. Tony Eissa, David P. Huston,
2003
7
Biomedical Aspects of Histamine: Current Perspectives
1994) mast cells to rapid degranulation. Also TNF, an important proinflammatory
cytokine, activates human skin (van Overveld et al. 1991) and rat peritoneal (
Brzezi ́nska-Błaszczyk et al. 2000, Olejnik and Brzezi ́nska-Błaszczyk 1998) mast
...
Nancy Khardori, Mohammed Shahid,
2010
8
Primary Immunodeficiency Diseases: Definition, Diagnosis, ...
Reduced degranula- tion can be observed in patients with FHL-3, FHL-4 or yet
undefined genetic disorders of degranulation [24, 110]. However, the test has not
yet been used in a sufficient number of patients with secondary HLH to judge its ...
Nima Rezaei, Asghar Aghamohammadi, Luigi D. Notarangelo,
2008
9
Postgraduate Haematology
Degranulation and secretion are processes whereby the contents of phagocytic
storage granules are released into the phagocytic vacuoles (degranulation) or
into the extracellular space (secretion). Degranulation and secretion can be ...
A. Victor Hoffbrand, Daniel Catovsky, Edward G. D. Tuddenham,
2011
10
Adenosine Receptors in Health and Disease
In the allergic response, antigens bind and crosslink IgE molecules bound to the
functional high-affinity receptor for IgE, FcεRI, on mast cells to induce
degranulation and the release of a broad spectrum of proinflammatory mediators
(Nilsson et ...
Constance N. Wilson, S. Jamal Mustafa,
2009
WIADOMOŚCI, KTÓRE ZAWIERAJĄ SŁOWO «DEGRANULATION»
Sprawdź, o czym dyskutuje się w prasie krajowej i zagranicznej oraz jak jest stosowane słowo
degranulation w wiadomościach.
Prevalence of allergic conjunctivitis among basic school children in …
How does this degranulation of mast cells occur? The conjunctiva mounts an antigen-specific response with Th-2 upon contact with an allergen ... «BMC Blogs Network, Lip 15»
Mutations in DOCK2 ID'd in Early-Onset Invasive Infections
In the T-, B-, and NK-cells, chemokine-induced migration and actin polymerization were defective; NK-cell degranulation was also affected. «Doctors Lounge, Cze 15»
The opioid peptide dynorphin A induces leukocyte responses via …
... the immune system, including leukocyte migration, degranulation and cytokine production. The mechanisms whereby opioid peptides induce ... «7thSpace Interactive, Cze 15»
Ibrutinib in the Management of B-cell Malignancies
... levels over the course of 12 cycles. There was an observed decrease in anti-immunoglobulin E (IgE)-stimulated basophil degranulation. «Targeted Oncology, Maj 15»
In Vivo Activation of Human NK Cells by Treatment with an …
... their degranulation upon exposure to K562 cells, as indicated by cell surface expression of CD107a; and their capacity to lyse K562 cells and ... «Journal of Virology, Maj 15»
The Nose Holds Clues in Vasculitis
"TREM1 is a signaling receptor on neutrophils and monocytes that amplifies pro-inflammatory cytokine production, degranulation, and ... «MedPage Today, Maj 15»
Neutrophil extracellular traps mediate bacterial liver damage
Phagocytosis and degranulation are the mechanisms they are probably best known to use, but they also employ NETs to—quite literally—trap ... «Nature.com, Kwi 15»
Sorafenib improves rituximab and ofatumumab efficacy by …
(d) For the degranulation assay, natural killer (NK) cells were negatively isolated from peripheral blood mononuclear cells of healthy donors ... «Nature.com, Kwi 15»
Adoptive T-cell immunotherapy for ganciclovir-resistant CMV …
... then assessed for IFN-γ expression and degranulation using surface CD107a expression. Data in each pie chart represents the proportion of ... «Nature.com, Mar 15»
US orphan status for AB Science's muscle-wasting drug
The drug blocks mast cell-mediated degranulation, the release of cytotoxic substances that could further damage motor nerves, and is already ... «PharmaTimes, Mar 15»