CO OZNACZA SŁOWO HYDROXYUREA
Hydroksykarbamid
Hydroxykarbamid lub hydroksymocznik jest lekiem przeciwnowotworowym, najpierw zsyntetyzowanym w 1869 roku, stosowanym w zaburzeniach mieloproliferacyjnych, w szczególności w przypadku wielowątroby i podstawowej trombocytemii. Jest również stosowany w celu zmniejszenia szybkości bolesnych ataków na chorobę sierpowatokomórkową i ma właściwości przeciwretrowirusowe w chorobach takich jak AIDS. To jest w Liście Podstawowych Leków Światowej Organizacji Zdrowia, lista najważniejszych leków potrzebnych w podstawowym systemie opieki zdrowotnej.
Definicja słowa hydroxyurea w słowniku
Definicja hydroksymocznika w słowniku jest lekiem, który zapobiega rozwojowi nowotworów i jest stosowany w leczeniu niektórych rodzajów raka, a także w leczeniu choroby sierpowatokrwinkowej i AIDS.
KSIĄŻKI POWIĄZANE ZE SŁOWEM «HYDROXYUREA»
Poznaj użycie słowa
hydroxyurea w następujących pozycjach bibliograficznych Książki powiązane ze słowem
hydroxyurea oraz krótkie ich fragmenty w celu przedstawienia kontekstu użycia w literaturze.
1
Defining a Novel Role of
Hydroxyurea on Erythrocytes
Recent findings implicate the red blood cell (RBC) as a determinant in physiological events that regulate the blood flow in the circulatory system.
Madushi Upendrika Raththagala,
2008
2
The AARP Guide to Pills: Essential Information on More Than ...
Hydroxyurea is a medicine that must be handled with care. People who are not
taking hydroxyurea should not be exposed to the powder in the open capsules. If
the powder from the capsule is spilled, it should be wiped up immediately with a ...
3
Meningiomas: Diagnosis, Treatment, and Outcome
Hydroxyurea is an antimetabolite that is orally absorbed, which allows ease of
administration. Its effects appear to be specific to the S phase of the cell cycle.
The molecular target is likely DNA synthesis mechanisms, and the drug causes ...
4
Drugs in Pregnancy and Lactation: A Reference Guide to Fetal ...
Antineoplastic PREGNANCY RECOMMENDATION: Limited Human Data -
Animal Data Suggest Risk BREASTFEEDING RECOMMENDATION:
Contraindicated PREGNANCY SUMMARY Although hydroxyurea is teratogenic
in animals, ...
Gerald G. Briggs, Roger K. Freeman, Sumner J. Yaffe,
2011
5
Disorders of Hemoglobin: Genetics, Pathophysiology, and ...
when hydroxyurea is used in myeloproliferative disorders. How and if the
myeloproliferative disorders equate to a disease without cancer-promoting
mutations but with lifelong expanded erythropoiesis remains to be seen. Acute
leukemia has ...
Martin H. Steinberg,
2001
6
HIV Chemotherapy: A Critical Review
Several pilot studies that examined the safety and efficacy of hydroxyurea
demonstrated that hydroxyurea monotherapy was not effective in decreasing
plasma HIV RNA, but in combination with didanosine a significant reductions in
viral load ...
Salvatore T. Butera,
2005
7
Frontiers in Medicinal Chemistry , Volume (4)
HYDROXYUREA PHARMACOKINETICS AND METABOLISM The
pharmacokinetics and pharmacodynamics of hydroxyurea have recently been
reviewed [20]. In general, hydroxyurea crosses the intestinal wall easily and
demonstrates ...
Atta-ur-Rahman, Allen B. Reitz, M. Iqbal Choudhary,
2009
8
Nitric Oxide Donors: For Pharmaceutical and Biological ...
0.15 mM hydroxyurea solution decomposes after 9 months at 4°C in neutral
aqueous solution [105]. Hydroxyurea also does not decompose in alkaline
solutions (pH 14, 30 min, 25°C) or in acidic conditions (pH 1–1.5, 3 h, 25°C) but
hydrolyzes ...
Peng George Wang, Tingwei Bill Cai, Naoyuki Taniguchi,
2005
9
Evidence-Based Hematology
Introduction Hydroxyurea is the only medication approved by the U.S. Food and
Drug Administration to treat SCD. The exact mechanism(s) of action resulting in
beneficial effects in SCD is not known. In addition to increasing fetal hemoglobin
...
Mark A. Crowther, Jeffrey Ginsberg, Holger Schünemann,
2009
10
Wintrobe's Clinical Hematology
Figure 33.12. effect of hydroxyurea on red blood cells. A. Peripheral blood smear
of patient with Hb SS prior to treatment with hydroxyurea showing sickle forms (
solid arrow), polychromasia, Howell-Jolly body (dashed arrow), and anisocytosis.
John P. Greer, Daniel A. Arber, Bertil Glader,
2013
WIADOMOŚCI, KTÓRE ZAWIERAJĄ SŁOWO «HYDROXYUREA»
Sprawdź, o czym dyskutuje się w prasie krajowej i zagranicznej oraz jak jest stosowane słowo
hydroxyurea w wiadomościach.
New Drug Offers Hope for Sickle Cell Patients
It uses a drug called hydroxyurea. The drug is already widely used in the U.S, but at Mulago it is still undergoing clinical trials. Kiragga and his ... «AllAfrica.com, Lip 15»
Third Rock's GBT swings for a $115M IPO to push its pill for sickle cell
Standard treatment for the disease relies on toxic treatments like hydroxyurea, or inconvenient blood transfusions and bone marrow transplants ... «FierceBiotech, Lip 15»
Screen children early for sickle cell disease
Dr Osei-Tutu hinted that plans were far advanced to have hydroxyurea (a drug for sickle-cell patients) on the National Health Insurance drug list ... «Graphic Online, Lip 15»
The Regulatory Quagmire Of Treatments For Sickle Cell Disease
Hydroxyurea is being studied in pediatric patients under the National Institute for Child Health And Human Development's (NICHD) program, ... «Forbes, Lip 15»
Ruxolitinib is useful for long-term treatment of polycythemia vera
In the study, 222 patients who were intolerant or resistant to hydroxyurea were randomized to open-label ruxolitinib 10 mg BID or best available ... «Medical News Today, Cze 15»
Persons with sickle cell disease can now benefit from NHF
"He got a stroke when he was five and they put him on hydroxyurea after that, so it is quite expensive. "And he has to do physiotherapy and stuff ... «Jamaica Observer, Cze 15»
CSCF observes World Sickle Cell Day
Through the initiative, approximately 20 percent more individuals suffering from the disease have been able to access Hydroxyurea, the only ... «New Pittsburgh Courier, Cze 15»
Federal employees honored for innovation
Rodgers' first major contribution to sickle cell research was work on developing a drug, hydroxyurea, which is used to treat it. Now his team at ... «Baltimore Sun, Cze 15»
Sickle Cell Disease and Clinical Trials
Hydroxyurea: Patients can take this oral medication to help reduce the frequency of pain crises and the need for blood transfusions. «FDA.gov, Cze 15»
Sickle Cell Is a Hereditary Disease of the Blood
A compound hydroxyurea reduces the frequency of painful crises possibly by stimulating the body to continue producing foetal haemoglobin, ... «AllAfrica.com, Cze 15»