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Approximately 66% of patients with near-haploid ALL have both the hypodiploid
and a doubled hypodiploid line; the remainder display only a hyperdiploid
karyotype, which represents a doubling of the chromosomes in the near-haploid
line.
2
Apoptotic Pathways as Targets for Novel Therapies in Cancer ...
Detection of Hypodiploid Nuclei as a Hallmark of Apoptosis — “Nicoletti Method”.
This method takes advantage of DNase activation and internucleosomal
DNAdegradation that becomes clearly visible in advanced apoptotic processes.
Marek Los, Spencer B. Gibson, 2006
There are two strategies for using DNA reference standards: one is to use a DNA
hypodiploid reference(s) to identify where the human DNA diploid G0/G, peak
should be located; this can be accomplished by using the reference as an
internal ...
Zbigniew Darzynkiewicz, J. Paul Robinson, Harry A. Crissman, 1994
4
Neuroimmunology Research Focus
8. o -co- HAM/TSP Control b) Figure 21. Apoptosis of peripheral blood CD4* T
cells induced by etoposide. a) A representative flow cytometry analysis of
hypodiploid DNA* cells in peripheral blood CD4+ T cells, treated with 10 uM of
etoposide ...
5
Emery and Rimoin's Principles and Practice of Medical Genetics
A hypodiploid clone with fewer than 46 chromosomes can be detected in about 5
—6% of ALL patients. There are three distinct subgroups of hypodiploidy in ALL,
that is near—haploidy (23—29 chromosomes), low hypo— diploidy (33—39 ...
David L. Rimoin, Reed E. Pyeritz, Bruce Korf, 2013
6
Multiple Myeloma and Related Disorders
Hypodiploidy as an indicator of poor prognosis Measurements of total DNA
content by flow cytometry have indicated that presence of a hypodiploid DNA
stemline is associated with a poor prognosis in patients with MM.73 This
observation has ...
Gosta Gahrton, Brian Durie, Diana Samson, 2004
7
Advances in Clinical Chemistry
The reduced DNA content of apoptotic nuclei resulted in an unequivocal
hypodiploid DNA peak in the red fluorescence channels; therefore, apoptotic
nuclei appear as a broad hypodiploid DNA peak (Sub G0) that is easily
discriminable from ...
8
Acute Lymphoblastic Leukemia: New Insights for the ...
According to news reporting originating from Aurora, Colorado, by NewsRx
correspondents, research stated, “The genetic basis of hypodiploid acute
lymphoblastic leukemia (ALL), a subtype of ALL characterized by aneuploidy and
poor ...
9
Hematopathology: Morphology, Immunophenotype, Cytogenetics, ...
In a large study [56] children with hypodiploid ALL were divided into three major
groups: near-haploid (23–29 chromosomes), low hypodiploid (33–39
chromosomes), and high hypodiploid (42–45 chromosomes). Survival analysis
showed a ...
Faramarz Naeim, P. Nagesh Rao, Wayne W. Grody, 2009
10
Cancer Cytogenetics: Chromosomal and Molecular Genetic ...
It occurs atan overall incidence of approximately 5%, independently of age (
Harrisonet al.,2004). Based on chromosome number and characteristic
cytogenetic features, hypodiploid cases cluster into three distinct subgroups:
nearhaploidy ...
Sverre Heim, Felix Mitelman, 2011
WIADOMOŚCI, KTÓRE ZAWIERAJĄ SŁOWO «HYPODIPLOID»
Sprawdź, o czym dyskutuje się w prasie krajowej i zagranicznej oraz jak jest stosowane słowo
hypodiploid w wiadomościach.
Cancer survivor serves at Rita's Italian Ice
Gracey Smith was diagnosed with hypodiploid acute lymphoblastic leukemia and is using her story to help spread awareness for other families ... «WJXT Jacksonville, Kwi 15»
Mansfield man is a candidate for LLS' 'Man of the Year'
Carr is competing in honor of nine-year-old Kinley Strohl, who is a survivor of Acute Lymphoblastic Leukemia-Hypodiploid. The man and ... «Richland Source, Mar 15»
Infection delays experimental cancer treatment for Delta teen …
When Kyle fell ill during a family camping trip in July of 2012 he was taken to a nearby hospital. He was soon diagnosed with hypodiploid acute ... «The Province, Gru 14»
Tsawwassen teen hoping to raise funds for experimental leukemia …
He was soon diagnosed with hypodiploid acute lymphoblastic leukemia. It was the day before his 16th birthday. After chemotherapy, radiation ... «Delta-Optimist, Lis 14»
Beyond the field, Laguna Hills baseball team works hard
... a Laguna Hills High student. Christian died of hypodiploid acute lymphoblastic leukemia, a rare type of cancer in children and adolescents. «OCRegister, Lip 14»
WRIGLEY TO FENWAY: Firefighter cyclists stop in Geneva on …
Henry “Hank” Schueler, the oldest of Matt and Susan Schueler's three children, died in 2007 from complications involving hypodiploid acute ... «Finger Lakes Times, Cze 14»
Team turns out for Allentown girl battling virulent leukemia
After further testing, physicians concluded that Molly actually had hypodiploid acute lymphoblastic leukemia -- a rarer cancer with a lower ... «Penn Live, Maj 14»
The battle of her little life and how she fought to overcome
... picture into TheBlaze Best Moments regarding her six-year-old daughter who was diagnosed with acute lymphoblastic leukemia-hypodiploid. «TheBlaze.com, Kwi 14»
3-Drug Regimen Active in Pretreated Myeloma
... the most common being del(13) in 34%, hyperdiploid in 32%, del(17p)/p53 in 22%, t(11;14) in 21%, hypodiploid in 11%, and t(4;14) in 10%. «MedPage Today, Gru 13»
Tsaw. teen to get bone marrow from brother
He was soon diagnosed with hypodiploid acute lymphoblastic leukemia. It was the day before his 16th birthday. The initial treatment of ... «Delta-Optimist, Wrz 12»
