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1
Parkinson's Disease and Movement Disorders
TABLE 10.4 TREATMENT OF PARKINSON'S DISEASE WITH L-DOPA
Advantages of L-dopa Therapy: • The vast majority of patients who start treatment
with L-dopa experience good to excellent functional benefit. • Tolerability is
usually good.
Joseph Jankovic, Eduardo Tolosa, 2007
2
Food Biotechnology, Second Edition
12.4.1 I -DOPA from Natural Sources L-DOPA is present in certain food, and L-
DOPA glycoside has been extracted from the broad bean (fava bean) Viciafaba (
83). The fava bean is one of the best plant sources of L-DOPA; clinical studies ...
Anthony Pometto, Kalidas Shetty, Gopinadhan Paliyath, 2005
3
Evaluation of D3 Dopamine Receptor Selective Compounds on ...
Parkinson's Disease (PD) is caused by the degeneration of dopaminergic neurons in the midbrain that innervate the striatum.
4
The Role of Neuroinflammation in
L-
DOPA-induced Dyskinesia
Figure 7: Timecourse of striatal mRNA expression of pro-inflammatory cytokines
and neuropeptides in rats primed with Vehicle or l-DOPA (12 mg/kg + 15 mg/kg of
benserazide) and acutely treated with Vehicle or l-DOPA. 6-OHDA lesioned rats ...
Christopher John Barnum, 2008
5
Psychiatric Side Effects of Prescription and ...
1989). Sleep disturbances are also common: nearly 30% of patients with
Parkinson's disease taking L-dopa have vivid dreams, and 7% will have night
terrors. Delirium may occur in nearly 5% of patients taking L-dopa for Parkinson's
disease.
Thomas Markham Brown, Alan Stoudemire, 1998
6
Neuropsychological Assessment
the most important treatment success story in neurology has been the use of L-
dopa, begun in 1967, to replace DA depletion due to degeneration of the sub-
stantia nigra. Since DA does not cross the blood-brain barrier, the DA precursor ...
Muriel Deutsch Lezak, 2004
7
Yao & Artusio's Anesthesiology: Problem-oriented Patient ...
Other studies have shown that L-dopa therapy can eventually lead to dyskinesia
due to fluctuating dopamine concentrations, prompting some physicians to save
L-dopa therapy for more advanced cases. L-dopa exhibits several drug ...
Fun-Sun F. Yao, Manuel L. Fontes, Vinod Malhotra, 2008
Only a few studies have compared responses to acute dopaminergic challenge
with chronic L-dopa treatment. Several of these have been reviewed in meta-
analyses.34-35 Concerning patients with early parkinsonism, in three studies
totaling ...
Ronald F. Pfeiffer, Zbigniew K. Wszolek, Manuchair Ebadi, 2004
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The Prokaryotes: Vol. 1: Symbiotic Associations, ...
The annual world production of L-DOPA is around 250 tons. L-DOPA (the
precursor of the neurotransmitter dopamine) is useful as a treatment for
Parkinson's disease. It had been mainly produced by a chemical synthetic
method that included ...
Martin Dworkin, Stanley Falkow, 2006
10
Birth, Life and Death of Dopaminergic Neurons in the ...
Our experiments demonstrated that a single intranigral administration of L-DOPA
induced nigrostriatal dopaminergic destruction similar to that inflicted by MPTP.
Analyses of TH protein expression revealed that L-DOPA caused a re- duction in
...
Giuseppe di Giovanni, Vincenzo Di Matteo, Ennio Esposito, 2009
WIADOMOŚCI, KTÓRE ZAWIERAJĄ SŁOWO «L-DOPA»
Sprawdź, o czym dyskutuje się w prasie krajowej i zagranicznej oraz jak jest stosowane słowo
L-dopa w wiadomościach.
Fishing for new ways to stop Parkinson's, a researcher makes big …
The main treatment, l-dopa, was developed 50 years ago; even though it can ease the symptoms of Parkinson's, it does nothing to stop the ... «Medical Xpress, Lip 15»
High Dopamine Levels Boost Risky-Decision Making
These findings are in line with previous reports that suggest dopamine drugs, such as L-DOPA, are connected to compulsive gambling in ... «Parkinson's News Today, Lip 15»
PARKINSON'S DISEASE NEWS
Whether the initial treatment for Parkinson's disease should consist of L-dopa, dopamine agonists, or MAO B inhibitors is uncertain. «Parkinson's Disease News, Lip 15»
Boosting Levels of Dopamine May Increase Risk-Taking
Also, after receiving L-DOPA, participants chose more risky options regardless of how much larger the potential reward was compared to the ... «PsychCentral.com, Lip 15»
Amarantus Bioscience Holdings Inc (OTCMKTS:AMBS) Gets A New …
It also has the potential to treat patients who suffer from “L-DOPA” induced dyskinesia. The new patent will help Amarantus to expand its ... «Journal Transcript, Lip 15»
Trader's Watch List: Code Rebel Corp (NASDAQ:CDRB), Acorda …
... an inhaled levodopa (L-dopa) under development for the episodic treatment of OFF episodes associated with Parkinson's disease (PD), was ... «Stock Transcript, Lip 15»
Dopamine makes gamblers take bigger risks
Previous research has linked drugs that increase dopamine, such as L-DOPA, with compulsive gambling in Parkinson's disease patients. «Health24, Lip 15»
Investors Are Watching: Acorda Therapeutics, Inc. (NASDAQ:ACOR …
... Acorda Therapeutics, Inc. (NASDAQ:ACOR) announced that data from a Phase 2b clinical trial of CVT-301, an inhaled levodopa (L-dopa) ... «Stock Transcript, Lip 15»
Parkinson's drug found to encourage the risk-taking behaviour of …
The drug levodopa or L-dopa, which is prescribed to patients with Parkinson's, has already been linked with changes in compulsive behaviour ... «The Independent, Lip 15»
Supplements seized
The products contained a combination of ingredients synephrine/ephedrine/ephedra, caffeine and L-dopa, which can cause serious health ... «Airdrie Echo, Lip 15»
