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1
Fundamentals of Forensic Science
Mitochondrial. DNA. (mtDNA). Mitochondria are small structures located within
practically all animal and plant cells (human red blood cells being one ofthe
exceptions). They function as energy mediators ofthe cell.They take energy
released ...
Max M. Houck, Jay A. Siegel, 2010
But another form of DNA, known as mitochondrial DNA (mtDNA), is found in the
cells' mitochondria (organelles responsible for the cell's energy metabolism)—
outside the nucleus. mtDNA contains only about 0.0006 percent of the genetic ...
Robert Kelly, David Thomas, 2009
mtDNA replication mechanism, and a wealth of data in vertebrate systems
support a general model for the initiation of H-strand mtDNA replication,
described by Shadel and Clayton (1997). In this model, RNA transcripts are
initiated at the LSP ...
Liza A. Pon, Eric A. Schon, 2011
4
Search Your Middle Eastern and European Genealogy: In the ...
For example, 9.0 of Ashkenazic (Jewish) women have mtDNA haplogroups that
follow the Cambridge Reference Sequence (CRS) (Anderson et al. 1981). That
means their matrilineal ancestry lines follow the reference sequence that all other
...
5
Conservation Biology: Foundations, Concepts, Applications
taxonomists consider phylogenetic analysis of mtDNA to be a superior, more
objective method of determining phylogeny because it is based entirely on
quantitative characters. Because it is maternally inherited, mtDNA can be used to
...
6
The Forensic Laboratory Handbook Procedures and Practice
The second and less commonly discussed type of DNA in a cell is mitochondrial
DNA (mtDNA). Mitochondria are very small organelles found outside the cell
nucleus within a cell's cytoplasm. Each mitochondrion has its own DNA. MtDNA
is ...
Ashraf Mozayani, Carla Noziglia, 2010
7
Disorders of Voluntary Muscle
Inheritance of mtDNA is strictly maternally in mammals (Giles et al., 1980;
Kaneda et al., 1995); new sequence variants are transmitted along maternal
lineages without the benefit of recombination with male mtDNA. Most individuals
have a ...
George Karpati, David Hilton-Jones, Robert C. Griggs, 2001
8
Neurology in Clinical Practice: The neurological disorders
Maternal inheritance differs fundamentally from Mendelian inheritance. A mother
carrying an mtDNA point mutation, for example, will pass it to all her children (
sons and daughters), but only her daughters will transmit it further to their
progeny.
Walter George Bradley, 2004
9
Mitochondrial Genetics and Cancer
Several reasons appear to account for mtDNA depletion, and the mechanisms
could be different in different diseases. For example, mutations in genes (DGUOK
, TK2, SUCLA2) involved in the salvaging pathway of dNTPs, required for mtDNA
...
10
American Indian
MtDNA, Y Chromosome Genetic Data, and the ...
As discussed above, there are several elements that make mtDNA particularly
useful in the study of historic population movements. The first is that unlike
nuclear DNA it is inherited from only one parent - the mother. This is because
human ...
WIADOMOŚCI, KTÓRE ZAWIERAJĄ SŁOWO «MTDNA»
Sprawdź, o czym dyskutuje się w prasie krajowej i zagranicznej oraz jak jest stosowane słowo
mtDNA w wiadomościach.
Limbs found in New Haven being tested by state lab
Samples suitable for mitochondrial DNA, or mtDNA, analysis are skeletal remains such as bones and teeth or human hair shafts, according to ... «New Haven Register, Lip 15»
Platysaurus attenboroughi: African Lizard Named after Sir David …
“Genetic analysis based on one mtDNA and two nDNA loci found Platysaurus attenboroughi to be genetically divergent from P. capensis and ... «Sci-News.com, Lip 15»
This Week in PLOS
"To our knowledge, this is the largest population analysis to date of mtDNA dynamics," the authors write, "revealing the age-imposed increase ... «GenomeWeb, Lip 15»
Stem cells could treat mitochondrial disease
The new study, published in Nature, shows that it is possible to revert skin cells containing damaged mitochondrial DNA (mtDNA) to pluripotent ... «BioNews, Lip 15»
Researchers take initial steps towards treatment of mitochondrial …
... were published online today in Nature through an article entitled “Metabolic rescue in pluripotent cells from patients with mtDNA disease”. «Ledger Gazette, Lip 15»
DNA Reveals These Red-Haired Chinese Mummies Come From …
But there were also “two West Eurasian mtDNA haplogroups H and K.” In looking more closely at the lineages and mutations, however, Li and ... «Forbes, Lip 15»
Researchers Make Progress In Search For Mitochondrial Disease …
"We demonstrate complementary strategies for generating genetically and functionally corrected PSCs for patients with mtDNA disease," the ... «Tech Times, Lip 15»
Cure For Mitochondrial Disease May Be Found In Stem Cells …
Source: Ma H, Folmes CDL, Wu J, et al. Metabolic rescue in pluripotent cells from patients with mtDNA disease. Nature. 2015. Comment. «Medical Daily, Lip 15»
Mitochondria Swap
Researchers have in the past worried that unmatched nuclear DNA and mitochondrial DNA (mtDNA) may cause problems in chimeric cells. «The Scientist, Lip 15»
Establishment of a coastal fish in the Azores: recent colonisation or …
PCR amplifications of mtDNA CR and nuclear DNA S7 were performed independently with the following pairs of primers: LPro1 ... «Nature.com, Lip 15»
