KSIĄŻKI POWIĄZANE ZE SŁOWEM «NITROGEN MUSTARD»
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Nitrogen Mustard Compounds: Advances in Research and ...
Nitrogen Mustard Compounds: Advances in Research and Application: 2011 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Nitrogen Mustard Compounds in a concise format.
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Dubois' Lupus Erythematosus
Nitrogen mustard (mechlorethamine) is a highly potent alkylating agent with
prolonged immunosuppressive and immunomodulatory effects. Although it is
infrequently used at the present time, a detailed review is in order because it
appears to ...
Daniel Jeffrey Wallace, Bevra Hahn, 2007
3
Weapons of Mass Destruction
Experiments found that tumors shrank following treatment with a type of nitrogen
mustard called HN-2, also known as mustine (Mustargenor mechloroethamine).
Its high toxicity and the introduction of many other chemotherapy options make ...
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Weapons of Mass Casualties and Terrorism Response Handbook
Nitrogen mustard (HN) is an oily, pale yellow or colorless liquid that is freely
soluble in organic solvents but insoluble in water. There are three variants of
nitrogen mustard: HN-1, HN-2, and HN-3. All three variants may be formed during
the ...
Charles Edward Stewart, 2006
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How Everyday Products Make People Sick: Toxins at Home and ...
Like the original toxin, nitrogen mustard is also a blistering agent, through either
inhalation or skin contact. It also has an even more potent capacity than its parent
compound to attack blood-forming cells. When the data from the U.S. nitrogen ...
Actuarial analysis yielded a four- year survival rate of 48.2 percent in their
patients receiving radiation therapy together with nitrogen mustard and 47.6
percent in those receiving radiotherapy alone. They concluded that nitrogen
mustard did ...
Topical nitrogen mustard (mechlorethamine) is an effective topical therapy for
mycosis fungoides (41–43). The mechanism of action when nitrogen mustard is
applied topically is not well defined and may not be related simply to its alkyl- ...
James O. Armitage, Bertrand Coiffier, Riccardo Dalla-Favera, 2009
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Report on Carcinogens (12th Ed. )
Cancer Studies in Humans When used as an antineoplastic agent, nitrogen
mustard hydrochloride usually is used in combination with other antineoplastic
drugs; however, it has been used alone to treat mycosis fungoides (IARC 1975,
1982).
Nat. Toxicology Program (NTP) (NIH), 2011
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Encyclopedia of Molecular Pharmacology
Nitrogen Mustards The first successful chemotherapy of malignant tumors was
recorded in 1942 when the first cytostatic drug named mechloretamine (^-
nitrogen mustard) was used. Later, a large series of nitrogen mustard analogues
was ...
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Drug Delivery: Principles and Applications
N Cl Cl O O O O N Cl Cl O O OH OH Hypoxia Reductase 4a O OH 4b 4 Relatively
stable nitrogen mustard N Cl Cl –O O N Cl –O O DNA + Aziridinium ring 4c 4d (
Reactive nitrogen mustard) Scheme 3. Bioreductive activation of prodrug 4.
Binghe Wang, Teruna J. Siahaan, Richard A. Soltero, 2005
WIADOMOŚCI, KTÓRE ZAWIERAJĄ SŁOWO «NITROGEN MUSTARD»
Sprawdź, o czym dyskutuje się w prasie krajowej i zagranicznej oraz jak jest stosowane słowo
nitrogen mustard w wiadomościach.
What Is Chemotherapy? The Ins And Outs Of Treatment, And How It …
... to World War II when, according to the American Cancer Society (ACS), the U.S. Army was studying a compound called nitrogen mustard. «Medical Daily, Lip 15»
From Ancient Tumors To Today's Breakthroughs: A Brief History Of …
The U.S. Department of Defense asked two pharmacologists from Yale to investigate how nitrogen mustard could potentially fight cancer or ... «Medical Daily, Cze 15»
US Government Tested Mustard Gas On Troops Based on Race
During the war, the U.S. government tested mustard gas, nitrogen mustard, and lewisite on 60,000 American soldiers to prepare the military for ... «Mintpress News, Cze 15»
New Research Finds Turmeric Compounds Helpful in Alleviating …
Sulfur mustard has a chemical cousin called nitrogen mustard that was developed and used for chemotherapy for certain blood cancers. In the ... «Digital Journal, Cze 15»
Timeline: Major cancer discoveries and treatments
1947: First successful chemotherapy treatment - Nitrogen Mustard - is used to treat Hodgkin Lymphoma. The treatment was discovered from an ... «ITV News, Cze 15»
ASCO: Triple Agent Tx Thwarts CLL Progress
... against the protein CD20, which is primarily found on the surface of B cells, and bendamustine is a nitrogen mustard alkylating agent. «MedPage Today, Maj 15»
How A Notorious Chemical Weapon Led To The Invention Of …
Mustard gas itself was out of the question, but the doctors came up with an alternate chemical called nitrogen mustard, and started looking for ... «io9, Maj 15»
“The Emperor of All Maladies”—The Amazing Biography of Cancer …
... Hallstead (total mastectomy), performed in 1898; the first use of radiation in 1928; and the first chemotherapy (nitrogen mustard) administered ... «OncLive, Kwi 15»
Waldenstrom macroglobulinemia: prognosis and management
Bendamustine is a nitrogen mustard which bears structural similarities to alkylating agents as well as purine analogs. A phase II trial of BR in 63 ... «Nature.com, Mar 15»
Our milestones: A recipe for success – the birth of combination …
When treating Hodgkin lymphoma patients, Professor Malpas remembers putting up drips with nitrogen mustard (mustine) “which made ... «Cancer Research UK, Mar 15»
