KSIĄŻKI POWIĄZANE ZE SŁOWEM «RACEMIC»
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1
Chemistry for Pharmacy Students: General, Organic and ...
3.5. Separation. of. stereoisomers: resolution. of. racemic. mixtures. A number of
compounds exist as racemic mixtures (i), Le. a mixture of equal amounts of two
enantiomers, (—) and (+). Often, one enantiomer shows medicinal properties.
Satyajit Sarker, Lutfun Nahar, 2013
A large number of chiral drugs, however, are sold as racemic mixtures. The
popular analgesic ibuprofen (the active ingredient in Motrin and many other
nonaspirin analgesics) is an example of a drug sold as a racemic mixture. For
racemic ...
William Brown, Christopher Foote, Brent Iverson, 2011
... polarized light. Such a 50 : 50 mixture of enantiomers is optically inactive and
is referred to as a racemic mixture, a racemic modification, or simply a racemate.
By definition, a racemic mixture is optically inactive, and its rotation is always 0°.
Marye Anne Fox, James K. Whitesell, 2004
4
Chirality in Drug Design and Development
Crystal Properties of Enantiomers and Racemic Compounds Statistically. 90-95%
of racemic species exist as racemic compounds while only 5-10% of racemic
species are conglomerates. These relative frequencies imply that the racemic ...
Indra K. Reddy, Reza Mehvar, 2004
5
The World of Chemistry: Essentials: Essentials
The decision about whether to sell a chiral drug in the racemic mixture or the
enantiomerically pure form has been left to the drug's manufacturer, although the
decision is subject to FDA approval. With the regulations in place, drug
companies ...
Melvin D. Joesten, John L. Hogg, Mary E. Castellion, 2006
6
Essentials of Organic Chemistry: For Students of Pharmacy, ...
At some stage, therefore, it might be necessary to have the means of separating
individual enantiomers from a racemic mixture. This is termed resolution.Thetra-
ditional method has been to convert enantiomers into diastereoisomers, because
...
7
Handbook of Polymer Synthesis: Second Edition
If the pseudochiral centers are enantiomeric, the diad is called racemic. A
polymer containing only meso diads is called isotactic, while a polymer
consisting of racemic diads only is named syndiotactic. Polypropene in which
meso and racemic ...
Hans R. Kricheldorf, Oskar Nuyken, Graham Swift, 2004
8
Enantiomer Separation: Fundamentals and Practical Methods
pseudoracemate or a solid solution.7,8 Accordingly, a racemic mixed crystal
refers to the crystal with a random alignment of the two enantiomers in the
defined positions to give both racemic and nonracemic crystals with a variety of
ee values ...
5.2.7 The Racemic Modification A mixture of equimolecular amounts of a pair of
enantiomers is known as racemic modification. A racemic modification will be
optically inactive, because the rotation caused by one half of the mixture is
exactly ...
A.K. Pahari, B.S. Chauhan, 2006
10
Competition Science Vision
(4) In racemic modifications, the optical inactivity is due to cancellation of rotation
caused by two molecules which are mirror images of each other. It is due to the
external compensation. (5) Optically inactive racemic modifications can be ...
WIADOMOŚCI, KTÓRE ZAWIERAJĄ SŁOWO «RACEMIC»
Sprawdź, o czym dyskutuje się w prasie krajowej i zagranicznej oraz jak jest stosowane słowo
racemic w wiadomościach.
Relmada Therapeutics Announces Filing of Clinical Trial Application …
As a single isomer of racemic methadone, d-Methadone (dextromethadone, REL-1017) has been shown to possess NMDA antagonist properties with virtually ... «PipelineReview.com, Lip 15»
Tonix Pharmaceuticals Presents Non-clinical Data on TNX-201 at …
Racemic IMH, a mixture of both the (R) and (S) isomers, had been widely used as a single-agent prescription medicine and as a component of combination drug ... «GlobeNewswire, Cze 15»
Deuterated drugs Relief from racemization
A single enantiomer of a drug is often more active than a racemic mixture. Indeed, the opposite enantiomer may lead to harmful side effects, and because of this, ... «Nature.com, Kwi 15»
Relmada Therapeutics Receives Health Canada Clearance to …
In contrast, racemic methadone is a long-acting narcotic producing typical opioid side effects used in the treatment of various pain states and as a substitution ... «PR Newswire, Kwi 15»
DeuteRx Demonstrates Novel Approach to Chiral Switching for …
ANDOVER, Mass.--(BUSINESS WIRE)--DeuteRx, LLC, is a research and development-focused biotechnology company dedicated to improving racemic small ... «Business Wire, Mar 15»
Tonix Pharmaceuticals Announces Clinical Progress on Potential …
Each cohort consisted of 15 subjects, who were randomly assigned in a 3:1:1 ratio to TNX-201, racemic isometheptene mucate (70 mg), or placebo, respectively. «GlobeNewswire, Sty 15»
Tonix Pharmaceuticals Receives IND Clearance for TNX-201 in …
Racemic IMH was a Drug Efficacy Study Implementation (DESI) ingredient that has been marketed as prescription single-agent and combination drug products ... «GlobeNewswire, Paz 14»
Chiral legal highs: Enantiomer separation with chiral HPLC mobile …
The mobile phase composition was investigated with individual solutions of five of the racemic compounds, namely 3-fluoroamphetamine, MDMA, ... «separationsNOW.com, Wrz 14»
Separation by levitation
'As it requires that the racemic crystal forms reliably, does not stick to enantiomerically pure crystals, and has a different density, it is more likely to be used in an ... «Chemistry World, Cze 14»
Tonix Pharmaceuticals Completes Pre-IND Meeting With FDA on …
"Selecting a single isomer of IMH for development can potentially reduce the toxicity associated with the racemic mixture based on our pharmacology data, ... «GlobeNewswire, Mar 14»
