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1
Immunoglobulins: Biologic Aspects and Clinical Uses
IgE combines with the tissue cells that are involved in reaginic hypersensitivity
reactions through the Fc portion of the molecules. IgE-forming cells localize in the
respiratory and gastrointestinal tracts. Locally formed IgE may play an important ...
2
Allergy Frontiers:Diagnosis and Health Economics
They showed that the reaginic activity was due to a new and distinct class of
immunoglobulins to which they gave the name of γE-globulin [15]. Essentially all
the reaginic activity in the sera of ten patients was lost upon absorption of the
sera ...
Ruby Pawankar, Stephen T. Holgate, Lanny J. Rosenwasser, 2009
Assay of Leukocyte-Sensitizing Reagins The in vitro assay of reaginic antibody
depends upon the apparently unique ability of this protein to sensitize specific
target cells for histamine release. Methods dependent upon other molecular ...
Frank J. Dixon, W. H. Taliaferro, Henry G. Kunkel, 1968
4
Mediators of the Allergic State: Recent Investigations. I
globulins. Amer. J. Dis. Child., 109:353, 1965. 33. Ishizaka, K., and Ishizaka, T.:
Physicochemical properties of reaginic antibody. I. Association of reaginic activity
with an immunoglobulin other than 7A- or 7G-globulin. /. Allergy, 37:169, 1966.
5
Textbook of Microbiology & Immunology
Sensitivity of the test depends on the stage of the disease. The test is 60-75%
sensitive in primary syphilis. The titers of antibodies, however, are relatively low.
The test is 100% sensitive in secondary syphilis and the serum reaginic antibody
...
6
Cancer and IgE: Introducing the Concept of AllergoOncology
Reaginic antibodies, namely IgE, were shown to be the primary mediators of
anaphylaxis, and the term “atopic reagins” was coined by Arthur F. Coca and Ella
F. Grove in 1925, referring to elements of human serum that were capable of ...
Manuel L. Penichet, Erika Jensen-Jarolim, 2010
7
Sexually Transmitted Infections: Diagnosis, Management, and ...
The diagnosis of neonatal syphilis is complicated by potential passive transfer of
maternal treponeme-specific and reaginic IgG-antibodies to the infant through the
placenta. These antibodies, however, are metabolized during the first 6–12 ...
Jonathan Zenilman, Mohsen Shahmanesh, 2011
8
Sexually Transmitted Infections: Diagnosis, Management, and ...
The diagnosis of neonatal syphilis is complicated by potential passive transfer of
maternal treponeme-specific and reaginic IgG-antibodies to the infant through the
placenta. These antibodies, however, are metabolized during the first 6–12 ...
Jonathan M. Zenilman, Mohsen Shahmanesh, 2011
9
Practical Handbook of Microbiology, Second Edition
Two main categories of serologic tests for syphilis are available: (1) tests for
nonspecific reaginic antibody and (2) tests for specific treponemal antibody. tests
for reaginic or anti-Cardiolipin antibody This is an unfortunate and confusing ...
Emanuel Goldman, Lorrence H Green, 2008
10
The Plasma Proteins V3: Structure, Function, and Genetic Control
F. IgE and Human Reaginic Antibodies Because of the identification of IgE with
human reaginic antibodies, great interest was aroused in the structure and
function of this least abundant class of human immunoglobulins, and now much
is ...
